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Datasheet SDS

RFP Antibody Pre-adsorbed

Rabbit Polyclonal

928 References
600-401-379S 600-401-379
25 µL 100 µg
WB, ELISA, IHC, IF, FC, EM, FISH, IP, Multiplex, Other
RFP, mScarlet, rRFP, tdTomato
Rabbit
$125.00 /Per Item
$299.00 /Per Item
Availability: Ships next business day Availability: Ships next business day
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

RFP Antibody Pre-adsorbed from Rockland Immunochemicals is a high-quality, rabbit polyclonal antibody specifically designed for the detection of red fluorescent protein (RFP) and its variants like mCherry, mScarlet, and tdTomato. This product is suitable for a broad range of applications including Western blot (WB), ELISA, immunohistochemistry (IHC), immunofluorescence (IF), flow cytometry (FC), and more. It is uniquely pre-adsorbed to minimize cross-reactivity, offering high specificity and sensitivity. With over 900 references, this product stands as a proven tool in the scientific community, supporting a wide range of research studies from cellular signaling to disease pathology.

Product Details

Anti-RFP (RABBIT) Antibody (Min X Hu Ms & Rt Serum Proteins) - 600-401-379
rabbit anti-RFP antibody, DsRed, rDsRed, Discosoma sp. Red Fluorescent Protein, Red fluorescent protein drFP583.
Rabbit
Polyclonal
IgG

Target Details

DsRed  - View All DsRed Products
RFP, mScarlet, rRFP, tdTomato
Recombinant Protein
The immunogen is a Red Fluorescent Protein (RFP) fusion protein corresponding to the full-length amino acid sequence (234aa) derived from the mushroom anemone Discosoma.
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Red Fluorescent Protein (Discosoma) coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Expect reactivity against RFP and its variants: mCherry, tdTomato, mBanana, mOrange, mPlum, mOrange and mStrawberry. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum and purified and partially purified Red Fluorescent Protein (Discosoma).  No reaction was observed against Human, Mouse or Rat serum proteins.

Application Details

ELISA, IF, IHC, WB
EM, FC, FISH, IP, Other, Multiplex  - View References
RFP Antibody Pre-adsorbed is designed for detecting RFP and its variants, tested across ELISA, Western blot, IF, IHC, and suitable for EM, FC, FISH, IP, and multiplex assays. It is applicable for ELISA in both sandwich and capture formats. Researchers should determine optimal titers for specific applications. Recommended starting dilutions are: ELISA 1:28,700 - 1:48,700; FC, IF, IHC 1:200 - 1:2,000; WB 1:1,000 - 1:5,000.

Formulation

Liquid (sterile filtered)
1.17 by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
(). A brainstem circuit for nausea suppression. Cell Rep.
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IHC, ICC, Histology
(). A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus. Curr Biol.
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Undefined
(). A dentate gyrusdentate gyrus-CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. Elife.
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IHC, ICC, Histology
(). A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles. Pharmaceutics.
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WB, IB, PCA
(). A general approach for engineering RTKs optically controlled with far-red light. Nat Methods.
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Undefined
(). A light-gated transcriptional recorder for detecting cell-cell contacts. Elife.
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IF, Confocal Microscopy
(). A novel spinal neuron connection for heat sensation. Neuron.
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(). A persistent behavioral state enables sustained predation of humans by mosquitoes. Elife.
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IF, Confocal Microscopy
(). Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. J Cereb Blood Flow Metab.
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IHC, ICC, Histology
(). Activation of LH GABAergic inputs counteracts fasting‐induced changes in tVTA/RMTG neurons. J Physiol.
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Undefined
(). Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion. Front Pharmacol.
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IHC, ICC, Histology
(). Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture. STAR Protoc.
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IF, Confocal Microscopy
(). Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells.
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IF, Confocal Microscopy; IHC, ICC, Histology
(). Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells.
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IHC, ICC, Histology
(). Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells. J Cereb Blood Flow Metab.
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Undefined
(). CENP-N promotes the compaction of centromeric chromatin. Nat Struct Mol Biol.
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IF, Confocal Microscopy
(). Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer Res.
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IHC, ICC, Histology
(). Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate. Neurosci Res.
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(). Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell.
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Undefined
(). Deciphering the origins and fates of steroidogenic lineages in the mouse testis. Cell Rep.
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IF, Confocal Microscopy
(). Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction. Nat Commun.
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IHC, ICC, Histology
(). Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells. Elife.
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IHC, ICC, Histology
(). Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo. J Biol Chem.
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IF, Confocal Microscopy
(). Dual-functional hydrogel system for spinal cord regeneration with sustained release of arylsulfatase B alleviates fibrotic microenvironment and promotes axonal regeneration. Biomaterials.
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IHC, ICC, Histology
(). Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders. Nat Cell Biol.
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IF, Confocal Microscopy
(). Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice. Front Cell Dev Biol.
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WB, IB, PCA
(). Generation of Piezo1‐CreER transgenic mice for visualization and lineage tracing of mechanical force responsive cells in vivo. Genesis.
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Undefined
(). Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis. Cell Res.
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Undefined
(). Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. J Cell Biol.
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Undefined
(). Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. Elife.
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IF, Confocal Microscopy
(). Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury. Exp Neurol.
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IF, Confocal Microscopy
(). Club cells employ regeneration mechanisms during lung tumorigenesis. Nature Communications
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IF, Confocal Microscopy
(). Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus. Scientific Reports
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IF, Confocal Microscopy
(). Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2. ELife
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Light-Sheet Microscopy (LSM); Other
(). Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway. Proceedings of the National Academy of Sciences of the United States of America
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IHC, ICC, Histology
(). PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis. International Journal of Biological Sciences
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IHC, ICC, Histology
(). Origin and function of activated fibroblast states during zebrafish heart regeneration. Nature Genetics
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IF, Confocal Microscopy
(). Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability. Scientific Reports
Applications
IF, Confocal Microscopy
(). The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration. Journal of Neuroinflammation
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IF, Confocal Microscopy
(). STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Science Alliance
Applications
IF, Confocal Microscopy
(). Intersectional mapping of multi-transmitter neurons and other cell types in the brain. Cell Reports
Applications
IHC, ICC, Histology
(). Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents. Development (Cambridge, England)
Applications
IF, Confocal Microscopy
(). PIEZO1 transduces mechanical itch in mice. Nature
Applications
IHC, ICC, Histology
(). Selectively Imaging Cranial Sensory Ganglion Neurons Using AAV-PHP.S. ENeuro
Applications
IHC, ICC, Histology
(). Co-targeting B-RAF and PTEN Enables Sensory Axons to Regenerate Across and Beyond the Spinal Cord Injury. Frontiers in Molecular Neuroscience
Applications
IHC, ICC, Histology
(). Multi-ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy. Cancer Reports (Hoboken, N.J.)
Applications
IHC, ICC, Histology
(). Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. ELife
Applications
IF, Confocal Microscopy
(). Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition. Cell and Tissue Research
Applications
IF, Confocal Microscopy
(). Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. Front Oncol.
Applications
IF, Confocal Microscopy
(). Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun.
Applications
IHC, ICC, Histology
(). Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses. Int J Mol Sci.
Applications
WB, IB, PCA
(). Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth. Sci Adv.
Applications
IF, Confocal Microscopy
(). Medullary kappa-opioid receptor neurons inhibit pain and itch through a descending circuit. Brain.
Applications
Undefined
(). Myosin V facilitates polarised E‐cadherin secretion. Traffic.
Applications
IHC, ICC, Histology
(). Neuromodulatory control of inhibitory network arborization in the developing postnatal neocortex. Sci Adv.
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IHC, ICC, Histology
(). Netrin1 and reelin signaling are required for the migration of anterolateral system neurons in the embryonic spinal cord. Pain.
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Undefined
(). Perirhinal Cortex LTP Does Not Require Astrocyte BDNF-TrkB Signaling. Cells.
Applications
IHC, ICC, Histology
(). Processing of information from the parafascicular nucleus of the thalamus through the basal ganglia. J Neurosci Res.
Applications
IF, Confocal Microscopy
(). Postnatal state transition of cardiomyocyte as a primary step in heart maturation. Protein Cell.
Applications
IF, Confocal Microscopy
(). Proton-gated anion transport governs macropinosome shrinkage. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Regulation of developmental hierarchy in Drosophila neural stem cell tumors by COMPASS and Polycomb complexes. Sci Adv.
Applications
IF, Confocal Microscopy
(). Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity. Elife.
Applications
IHC, ICC, Histology
(). Robust and sensitive in situ RNA detection using Yn-situ. Cell Rep Methods.
Applications
IF, Confocal Microscopy
(). Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development. Cell Rep.
Applications
IF, Confocal Microscopy
(). Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours. Brain.
Applications
IHC, ICC, Histology
(). Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nat Neurosci.
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Undefined
(). Sticks and Stones, a conserved cell surface ligand for the Type IIa RPTP Lar, regulates neural circuit wiring in Drosophila. Elife.
Applications
IHC, ICC, Histology
(). Strong Aversive Conditioning Triggers a Long-Lasting Generalized Aversion. Front Cell Neurosci.
Applications
IHC, ICC, Histology
(). Subcellular proteomics of dopamine neurons in the mouse brain. Elife.
Applications
IHC, ICC, Histology
(). Structural and Functional Support by Left Atrial Appendage Transplant to the Left Ventricle after a Myocardial Infarction. Int J Mol Sci.
Applications
iDISCO
(). The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity. J Cell Sci.
Applications
IF, Confocal Microscopy
(). The essential M. tuberculosis Clp protease is functionally asymmetric in vivo. Sci Adv.
Applications
WB, IB, PCA
(). The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia.
Applications
IHC, ICC, Histology
(). Targeting thalamic circuits rescues motor and mood deficits in PD mice. Nature.
Applications
Undefined
(). Transcriptional regulation of neural stem cell expansion in the adult hippocampus. Elife.
Applications
ISH, FISH
(). Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nat Cell Biol.
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Undefined
(). Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles. J Control Release.
Applications
IHC, ICC, Histology
(). An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury. Neuron.
Applications
IHC, ICC, Histology
(). Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Nat Protoc.
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Undefined
(). The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. Acta Neuropathol Commun.
Applications
IHC, ICC, Histology
(). Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality. Acta Physiol (Oxf).
Applications
ISH, FISH
(). Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs. Chem Phys Lipids.
Applications
Undefined
(). Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes. J Extracell Vesicles.
Applications
IF, Confocal Microscopy
(). The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis. J Biol Chem.
Applications
IHC, ICC, Histology
(). Adaptive differentiation promotes intestinal villus recovery. Dev Cell.
Applications
Undefined
(). Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses. JCI Insight.
Applications
IHC, ICC, Histology
(). IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation. Nat Immunol.
Applications
Undefined
(). The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development
Applications
IF, Confocal Microscopy
(). Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells. Immunity.
Applications
Undefined
(). Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab.
Applications
IF, Confocal Microscopy
(). SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport. Dev Cell.
Applications
Undefined
(). Subfornical organ interleukin 1 receptor: a novel regulator of spontaneous and conditioned fear associated behaviors in mice. Brain Behav Immun.
Applications
IHC, ICC, Histology
(). Combined Kelch-Like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice. J Am Soc Nephrol.
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Undefined
(). Subcellular and regional localization of mRNA translation in midbrain dopamine neurons. Cell Rep.
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IHC, ICC, Histology
(). Twist regulates Yorkie activity to guide lineage reprogramming of syncytial alary muscles. Cell Rep.
Applications
IF, Confocal Microscopy
(). Genome Editing with AAV-BR1-CRISPR in Postnatal Mouse Brain Endothelial Cells. Int J Biol Sci.
Applications
IHC, ICC, Histology
(). Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei. Nucleic Acids Res.
Applications
IP, Co-IP; ISH, FISH
(). Median raphe region GABAergic neurons contribute to social interest in mouse. Life Sci.
Applications
IHC, ICC, Histology
(). High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells. STAR Protoc.
Applications
IF, Confocal Microscopy
(). AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Molecular Therapy
Applications
IF, Confocal Microscopy
(). Iron contributes to photoreceptor degeneration and Müller glia proliferation in the zebrafish light-treated retina. Exp Eye Res.
Applications
Undefined
(). DRGquant: A new modular AI-based Pipeline for 3D Analysis of the DRG. J Neurosci Methods.
Applications
IHC, ICC, Histology
(). Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo. J Cell Biol.
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Undefined
(). Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry. Dev Cell.
Applications
IF, Confocal Microscopy
(). Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel. Frontiers in Neuroscience
Applications
IHC, ICC, Histology
(). A deep learning approach to identifying immunogold particles in electron microscopy images. Scientific Reports
Applications
Immuno-EM
(). CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge. International Journal of Molecular Sciences
Applications
Other
(). Drp1 is required for AgRP neuronal activity and feeding. ELife
Applications
Immuno-EM
(). Control of feeding by Piezo-mediated gut mechanosensation in Drosophila. ELife
Applications
IHC, ICC, Histology
(). Widespread labeling and genomic editing of the fetal central nervous system by in utero CRISPR AAV9-PHP.eB administration. Development (Cambridge, England)
Applications
IHC, ICC, Histology
(). Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). Decoding neuronal composition and ontogeny of individual hypothalamic nuclei. Neuron.
Applications
IF, Confocal Microscopy
(). Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity. Genes Cells.
Applications
IF, Confocal Microscopy
(). Repetitive injury and absence of monocytes promote astrocyte self‐renewal and neurological recovery. Glia.
Applications
IHC, ICC, Histology
(). Increased Callosal Connectivity in Reeler Mice Revealed by Brain-Wide Input Mapping of VIP Neurons in Barrel Cortex. Cereb Cortex.
Applications
ISH, FISH
(). Activation of preoptic tachykinin 1 neurons promotes wakefulness over sleep and volatile anesthetic-induced unconsciousness. Curr Biol.
Applications
IHC, ICC, Histology
(). CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell.
Applications
WB, IB, PCA
(). Stromal SOX2 upregulation promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population. Dev Cell.
Applications
IF, Confocal Microscopy
(). Area postrema cell types that mediate nausea-associated behaviors. Neuron.
Applications
IHC, ICC, Histology
(). Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells. Stem Cell Reports
Applications
Undefined
(). A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis. Cell Rep.
Applications
IHC, ICC, Histology
(). Using a reporter mouse to map known and novel sites of GLP-1 receptor expression in peripheral tissues of male mice. Endocrinology.
Applications
Undefined
(). Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. Elife
Applications
WB, IB, PCA
(). Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res
Applications
WB, IB, PCA
(). PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat. Cell Rep.
Applications
IF, Confocal Microscopy
(). Morphine acts on spinal dynorphin neurons to cause itch through disinhibition. Sci Transl Med.
Applications
Undefined
(). Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex. Nat Commun.
Applications
WB, IB, PCA
(). Hippocampal neurons respond to brain activity with functional hypoxia. Mol Psychiatry.
Applications
IF, Confocal Microscopy
(). A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell.
Applications
Undefined
(). Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain. Cell Rep.
Applications
IHC, ICC, Histology
(). Olig3 regulates early cerebellar development. Elife
Applications
IF, Confocal Microscopy
(). Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas. Cell Rep.
Applications
IF, Confocal Microscopy
(). Intravital microscopy of dynamic single-cell behavior in mouse mammary tissue. Nat Protoc.
Applications
Undefined
(). Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation. Nat Commun.
Applications
IF, Confocal Microscopy
(). Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum. PLoS Biol.
Applications
IHC, ICC, Histology
(). Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior. Advanced Functional Materials
Applications
IHC, ICC, Histology
(). An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis. Science Advances
Applications
WB, IB, PCA
(). Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model. Cells
Applications
IHC, ICC, Histology
(). Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release. Brain Sciences
Applications
IHC, ICC, Histology
(). Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning. Cell Reports
Applications
IHC, ICC, Histology
(). Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling. ELife
Applications
IF, Confocal Microscopy
(). Functional expression of TMEM16A in taste bud cells. The Journal of Physiology
Applications
IHC, ICC, Histology
(). Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature Protocols
Applications
IF, Confocal Microscopy
(). Optogenetic axon guidance in embryonic zebrafish. Star Protocols
Applications
IHC, ICC, Histology
(). The bone microenvironment invigorates metastatic seeds for further dissemination. Cell.
Applications
IF, Confocal Microscopy
(). Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators. Elife.
Applications
WB, IB, PCA
(). The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. J Neurosci Res.
Applications
IHC, ICC, Histology
(). Cascade diversification directs generation of neuronal diversity in the hypothalamus. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia. Stem Cells Transl Med.
Applications
IF, Confocal Microscopy
(). MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development. Front Neurosci.
Applications
IF, Confocal Microscopy
(). NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature.
Applications
Undefined
(). Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors. Neuron.
Applications
Undefined
(). Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions. Elife.
Applications
IHC, ICC, Histology
(). Analysis of growth cone extension in standardized coordinates highlights self-organization rules during wiring of the Drosophila visual system. PLoS Genet.
Applications
IHC, ICC, Histology
(). Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism. Prog Neurobiol.
Applications
IF, Confocal Microscopy
(). Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol.
Applications
IF, Confocal Microscopy
(). VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol.
Applications
WB, IB, PCA
(). Protein-retention expansion microscopy for visualizing subcellular organelles in fixed brain tissue. J Neurosci Methods.
Applications
IHC, ICC, Histology
(). Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder. Cell Rep.
Applications
IHC, ICC, Histology
(). SARS-CoV-2 infection in the mouse olfactory system. Cell Discov.
Applications
IF, Confocal Microscopy
(). Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Cell Rep.
Applications
IHC, ICC, Histology
(). A genetically defined insula-brainstem circuit selectively controls motivational vigor. Cell.
Applications
Undefined
(). Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis. Cell Rep.
Applications
IHC, ICC, Histology
(). Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proc Natl Acad Sci USA
Applications
IHC, ICC, Histology
(). Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature.
Applications
IF, Confocal Microscopy
(). The Coiled‐Coil Forming Peptide (KVSALKE)5 Is a Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Adv Healthc Mater.
Applications
Undefined
(). Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis. Nat Aging.
Applications
IF, Confocal Microscopy; TUNEL
(). Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities. PLoS One
Applications
IF, Confocal Microscopy
(). Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair. Cell Calcium.
Applications
Undefined
(). Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. Nat Commun.
Applications
IF, Confocal Microscopy
(). Inactivation of Hedgehog signal transduction in adult astrocytes results in region-specific blood–brain barrier defects. Proc Natl Acad Sci USA
Applications
IHC, ICC, Histology
(). Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev.
Applications
IHC, ICC, Histology
(). Covert capture and attenuation of a hippocampus-dependent fear memory. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice. Science.
Applications
IHC, ICC, Histology
(). Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI Insight.
Applications
IF, Confocal Microscopy
(). Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron.
Applications
IHC, ICC, Histology
(). Quantification of adipocyte numbers following adipose tissue remodeling. Cell Rep.
Applications
IHC, ICC, Histology
(). Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol.
Applications
Undefined
(). Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes. J Cell Biol.
Applications
Undefined
(). Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma. Nat Cancer.
Applications
Undefined
(). Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. Nat Commun.
Applications
IF, Confocal Microscopy
(). Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep.
Applications
IF, Confocal Microscopy
(). Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Sci Adv.
Applications
IHC, ICC, Histology
(). Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Rep.
Applications
IHC, ICC, Histology
(). Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis. Sci Adv.
Applications
IHC, ICC, Histology
(). IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Sci Adv.
Applications
IHC, ICC, Histology
(). Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory. Sci Immunol.
Applications
Undefined
(). Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production. iScience.
Applications
IF, Confocal Microscopy
(). Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol.
Applications
IF, Confocal Microscopy
(). Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol.
Applications
IHC, ICC, Histology
(). The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. Dev Cell.
Applications
WB, IB, PCA
(). The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell.
Applications
IHC, ICC, Histology
(). Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv.
Applications
IF, Confocal Microscopy
(). Constructing an adult orofacial premotor atlas in Allen mouse CCF. Elife
Applications
IHC, ICC, Histology
(). Pancreatic β-cells communicate with vagal sensory neurons. Gastroenterology
Applications
Undefined
(). Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metab.
Applications
IF, Confocal Microscopy
(). Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. J Exp Med.
Applications
Undefined
(). ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain. Sci Adv.
Applications
IF, Confocal Microscopy
(). Transcriptional profiling of sequentially generated septal neuron fates. Elife.
Applications
IF, Confocal Microscopy
(). The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development
Applications
IHC, ICC, Histology; Other
(). Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states. Sci Rep.
Applications
IHC, ICC, Histology
(). HepaCAM controls astrocyte self-organization and coupling. Neuron.
Applications
IF, Confocal Microscopy
(). Cell of origin influences pancreatic cancer subtype. Cancer Discov.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4. EMBO J.
Applications
IHC, ICC, Histology
(). Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun.
Applications
IF, Confocal Microscopy
(). A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers. Nat Cell Biol.
Applications
Undefined
(). An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife.
Applications
IHC, ICC, Histology
(). Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. J Exp Med.
Applications
IF, Confocal Microscopy
(). Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Phychiatry.
Applications
IHC, ICC, Histology
(). Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells. iScience.
Applications
IF, Confocal Microscopy
(). Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting. Cell Rep.
Applications
IHC, ICC, Histology; Other
(). Genetically identified amygdala–striatal circuits for valence-specific behaviors. Nat Neurosci.
Applications
Undefined
(). A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol.
Applications
IHC, ICC, Histology
(). A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol.
Applications
Undefined
(). Ronin governs the metabolic capacity of the embryonic lineage for post‐implantation development. EMBO Reports
Applications
IF, Confocal Microscopy
(). Microglia sense neuronal activity via GABA in the early postnatal hippocampus. Cell Rep.
Applications
IHC, ICC, Histology
(). Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biol Open
Applications
IF, Confocal Microscopy
(). Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Mol Metab.
Applications
IF, Confocal Microscopy
(). Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes. Mol Biol Cell.
Applications
IF, Confocal Microscopy
(). I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. Development
Applications
IF, Confocal Microscopy
(). RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. PLoS Biol.
Applications
IHC, ICC, Histology
(). Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice. Endocrinology
Applications
Undefined
(). Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. Elife.
Applications
IHC, ICC, Histology
(). Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors. Elife.
Applications
IHC, ICC, Histology
(). Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. Nat Commun.
Applications
IHC, ICC, Histology
(). Tools for efficient analysis of neurons in a 3D reference atlas of whole mouse spinal cord. Cell Rep Methods.
Applications
IHC, ICC, Histology
(). Parallel processing by distinct classes of principal neurons in the olfactory cortex. Elife.
Applications
IHC, ICC, Histology
(). Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development. EMBO Rep.
Applications
WB, IB, PCA
(). Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Cell Rep.
Applications
IHC, ICC, Histology; Other
(). Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention. Commun Biol.
Applications
IHC, ICC, Histology
(). Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. Circulation.
Applications
IF, Confocal Microscopy
(). Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex. Elife.
Applications
IF, Confocal Microscopy
(). Functional diversity for body actions in the mesencephalic locomotor region. Cell.
Applications
IHC, ICC, Histology
(). Derivation of airway basal stem cells from human pluripotent stem cells. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Identifying oligodendrocyte enhancers governing Plp1 expression. Hum Mol Genet.
Applications
IF, Confocal Microscopy
(). Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. Cell Rep.
Applications
IHC, ICC, Histology
(). Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron.
Applications
IHC, ICC, Histology
(). Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol.
Applications
IHC, ICC, Histology
(). Fibroblast dedifferentiation as a determinant of successful regeneration. Dev Cell.
Applications
IF, Confocal Microscopy
(). Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum. Nat Commun.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli. Neurobiol Stress.
Applications
IHC, ICC, Histology
(). Mitochondrial ROS induced lysosomal dysfunction and autophagy impairment in an animal model of congenital hereditary endothelial dystrophy. Invest Ophthalmol Vis Sci.
Applications
IHC, ICC, Histology
(). TMEM16A and TMEM16B modulate pheromone-evoked action potential firing in mouse vomeronasal sensory neurons. eNeuro.
Applications
IHC, ICC, Histology
(). STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. J Neurosci
Applications
Undefined
(). TGFβ signaling activated by cancer-associated fibroblasts determines the histological signature of lung adenocarcinoma. Cancer Res.
Applications
IF, Confocal Microscopy
(). Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice. J Mol Endocrinol.
Applications
IHC, ICC, Histology
(). Live-Cell Imaging Technique to Visualize DAMPs Release During Regulated Cell Death. Methods Mol Biol.
Applications
Undefined
(). Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice. PLoS One
Applications
IHC, ICC, Histology
(). Modulation of both intrinsic and extrinsic factors additively promotes rewiring of corticospinal circuits after spinal cord injury. J Neurosci.
Applications
Undefined
(). NPY released from GABA neurons of the dentate gyrus specially reduces contextual fear without affecting cued or trace fear. Front Synaptic Neurosci.
Applications
IHC, ICC, Histology
(). Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation. Front Cell Dev Biol.
Applications
IHC, ICC, Histology
(). The impact of SST and PV interneurons on nonlinear synaptic integration in the neocortex. eNeuro.
Applications
IF, Confocal Microscopy
(). Experience-dependent inhibitory plasticity is mediated by CCK+ basket cells in the developing dentate gyrus. J Neurosci.
Applications
IHC, ICC, Histology
(). Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution. Methods Mol Biol.
Applications
Undefined
(). An Optimized Whole‐Mount Immunofluorescence Method for Shoot Apices. Curr Protoc.
Applications
Undefined
(). Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation In Vivo with CalExflox Mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1‐transgenic mice. Glia.
Applications
IHC, ICC, Histology
(). Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson's disease and OCD-like behaviors in mice. Mol Psychiatry.
Applications
IHC, ICC, Histology
(). Level of hM4D (Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus. eNeuro.
Applications
IHC, ICC, Histology
(). Reconsidering the border between the visual and posterior parietal cortex of mice. Cereb Cortex.
Applications
IHC, ICC, Histology
(). Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell Rep.
Applications
IHC, ICC, Histology
(). Mouse models for studying hippocampal adult neural stem cell biology. Methods Mol Biol.
Applications
Undefined
(). Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol.
Applications
IF, Confocal Microscopy
(). An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish. Elife.
Applications
IHC, ICC, Histology
(). An inhibitory hippocampal-thalamic pathway modulates remote memory retrieval. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird. Nat Commun.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Early stem cell aging in the mature brain. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Photoreceptor nanotubes mediate the in vivo exchange of intracellular material. EMBO J.
Applications
IF, Confocal Microscopy
(). GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum. eNeuro
Applications
IF, Confocal Microscopy
(). Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun.
Applications
IF, Confocal Microscopy
(). Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol.
Applications
IHC, ICC, Histology
(). Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep.
Applications
IHC, ICC, Histology
(). Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter. IBRO Rep.
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
(). Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol.
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
(). The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse. Cell Rep.
Applications
IF, Confocal Microscopy
(). Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. Neural Dev.
Applications
IF, Confocal Microscopy
(). Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea. Sci Rep.
Applications
IF, Confocal Microscopy
(). Transcriptional activities of human elongation factor-1α and cytomegalovirus promoter in transgenic dogs generated by somatic cell nuclear transfer. PLoS One.
Applications
IHC, ICC, Histology
(). Indian hedgehog in craniofacial neural crest cells links to skeletal malocclusion by regulating associated cartilage formation and gene expression. FASEB J.
Applications
Undefined
(). Yolk-sac-derived macrophages progressively expand in the mouse kidney with age. Elife
Applications
IF, Confocal Microscopy
(). Somatostatin neurons of the bed nucleus of stria terminalis enhance associative fear memory consolidation in mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes. Cell Struct Funct.
Applications
WB, IB, PCA
(). Activity-dependent dendritic elaboration requires Pten. Neurobiol Dis.
Applications
IHC, ICC, Histology
(). Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Effects of nectin-3 misexpression on dendritic spine density during the postnatal development of layer 2/3 cortical neurons. Neural Dev
Applications
IHC, ICC, Histology
(). Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol.
Applications
IF, Confocal Microscopy
(). Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. Neural Dev.
Applications
IHC, ICC, Histology
(). Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology
Applications
IHC, ICC, Histology
(). Neurogenic Niche Conversion Strategy Induces Migration and Functional Neuronal Differentiation of Neural Precursor Cells Following Brain Injury. Stem Cells Dev.
Applications
IF, Confocal Microscopy
(). Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors. Cell Mol Life Sci.
Applications
IF, Confocal Microscopy
(). A Feedforward Circuit Regulates Action Selection of Pre-mating Courtship Behavior in Female Drosophila. Curr Biol.
Applications
IHC, ICC, Histology
(). Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors. Neuron
Applications
IHC, ICC, Histology
(). Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. J Comp Neurol.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Front Mol Neurosci.
Applications
IHC, ICC, Histology
(). Development and characterization of an Otp conditional loss of function allele. Genesis
Applications
IF, Confocal Microscopy
(). Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell.
Applications
IF, Confocal Microscopy
(). Placental gene editing via trophectoderm-specific Tat-Cre/loxP recombination. Development
Applications
Undefined
(). Microstimulation of primate neocortex targeting striosomes induces negative decision-making. Eur J Neurosci.
Applications
Undefined
(). Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. J Exp Med.
Applications
IF, Confocal Microscopy
(). Genetic ablation of SOD1G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression. bioRxiv
Applications
IF, Confocal Microscopy
(). Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. Neurogastroenterol Motil. Neurogastroenterol Motil.
Applications
IF, Confocal Microscopy
(). Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer
Applications
Undefined
(). Astrocytes shape the plastic response of adult cortical neurons to vision loss. Glia
Applications
IHC, ICC, Histology
(). Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron
Applications
Undefined
(). Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus. bioRxiv
Applications
IHC, ICC, Histology
(). Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Generation of transgenic mice that conditionally express microRNA miR-145. Genesis.
Applications
IHC, ICC, Histology
(). In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Brain
Applications
IHC, ICC, Histology
(). Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Curr Biol.
Applications
IF, Confocal Microscopy
(). A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus. ELife
Applications
IHC, ICC, Histology
(). Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner. Elife
Applications
WB, IB, PCA
(). Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. Cell Mol Gastroenterol Hepatol.
Applications
IF, Confocal Microscopy
(). Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell.
Applications
ISH, FISH
(). TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep.
Applications
IHC, ICC, Histology
(). Regulation of the Unfolded Protein Response by BiP AMPylation protects photoreceptors from light-dependent degeneration. bioRxiv
Applications
IHC, ICC, Histology
(). Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem.
Applications
IF, Confocal Microscopy
(). A central amygdala-globus pallidus circuit conveys unconditioned stimulus information and controls fear learning. J Neurosci.
Applications
IHC, ICC, Histology
(). G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv
Applications
WB, IB, PCA
(). Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. Mol Ther.
Applications
IHC, ICC, Histology
(). Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. J Vis Exp.
Applications
IF, Confocal Microscopy
(). Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development.
Applications
IF, Confocal Microscopy
(). Characterization of a Knockin Mouse Line Expressing a Fusion Protein of Kappa Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging Via CLARITY [published online ahead of print, 2020 Jun 19]. eNeuro. 2020;ENEURO.0028-20.2020. doi:10.1523/ENEURO.0028-20.2020
Applications
IHC, ICC, Histology
(). A Human Fallopian Tube Epithelial Cell Culture Model to Study Host Responses to Chlamydia trachomatis Infection Infect Immun.
Applications
IF, Confocal Microscopy
(). Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. PLoS Genet
Applications
IF, Confocal Microscopy
(). Rapid image deconvolution and multiview fusion for optical microscopy. Nat Biotechnol.
Applications
IHC, ICC, Histology
(). Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development.
Applications
IHC, ICC, Histology
(). Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging. bioRxiv
Applications
IP, Co-IP
(). An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol.
Applications
IF, Confocal Microscopy
(). Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter J Mol Cell Cardiol.
Applications
IF, Confocal Microscopy
(). The neurokinin-1 receptor is expressed with gastrin-releasing peptide receptor in spinal interneurons and modulates itch. J Neurosci.
Applications
IHC, ICC, Histology
(). A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue. Oncotarget.
Applications
IHC, ICC, Histology
(). Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis. Dev Cell.
Applications
Undefined
(). Development of a mouse reporter strain for the purinergic P2X2 receptor. eNeuro.
Applications
IF, Confocal Microscopy
(). A cortico-collicular circuit for accurate orientation to shelter during escape. bioRxiv
Applications
IHC, ICC, Histology
(). Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun.
Applications
IF, Confocal Microscopy
(). ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol.
Applications
IHC, ICC, Histology
(). Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun.
Applications
IHC, ICC, Histology
(). CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. J Invest Dermatol.
Applications
IF, Confocal Microscopy
(). RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism. Curr Biol.
Applications
IF, Confocal Microscopy
(). Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Cell Rep
Applications
IF, Confocal Microscopy
(). Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism. Nat Commun.
Applications
IF, Confocal Microscopy
(). A lineage-tracing tool to map the fate of hypoxic tumour cells. Dis Model Mech.
Applications
IF, Confocal Microscopy
(). Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation. Sci Adv.
Applications
IF, Confocal Microscopy
(). LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Sci Adv.
Applications
IF, Confocal Microscopy
(). Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet.
Applications
IHC, ICC, Histology
(). Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep.
Applications
IF, Confocal Microscopy
(). A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues. Proc Natl Acad Sci U S A.
Applications
IF, Confocal Microscopy
(). Defining the lineage of thermogenic perivascular adipose tissue. Nat Metab.
Applications
IF, Confocal Microscopy
(). Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nat Biomed Eng.
Applications
IF, Confocal Microscopy
(). Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury. Cereb Cortex.
Applications
IHC, ICC, Histology
(). Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Dev Cell.
Applications
IF, Confocal Microscopy
(). Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death. J Cell Biol.
Applications
Undefined
(). Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun.
Applications
IHC, ICC, Histology
(). Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons Proc Natl Acad Sci U S A.
Applications
IHC, ICC, Histology
(). Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene.
Applications
IF, Confocal Microscopy
(). Development of a genetically-encoded oxytocin sensor. bioRxiv
Applications
IHC, ICC, Histology
(). AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature.
Applications
IHC, ICC, Histology
(). Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. Elife.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J.
Applications
IHC, ICC, Histology
(). CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation. Neuron.
Applications
IF, Confocal Microscopy
(). A genetic system for tissue-specific inhibition of cell proliferation. Development.
Applications
IHC, ICC, Histology
(). Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife.
Applications
ISH, FISH
(). Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons. Nat Commun.
Applications
IHC, ICC, Histology
(). Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. Elife.
Applications
IF, Confocal Microscopy
(). VE-cadherin endocytosis controls vascular integrity and patterning during development. J Cell Biol.
Applications
IF, Confocal Microscopy
(). Adipokines set neural tone by regulating synapse number. Cell Metab.
Applications
IF, Confocal Microscopy
(). Cocaine Triggers Glial-Mediated Synaptogenesis. Biol Psychiatry.
Applications
IHC, ICC, Histology
(). The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation. Cell Rep.
Applications
IF, Confocal Microscopy
(). Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design. Cell.
Applications
WB, IB, PCA
(). ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells. bioRxiv
Applications
WB, IB, PCA
(). Phox2a defines a developmental origin of the anterolateral system in mice and humans. Cell Rep
Applications
IHC, ICC, Histology
(). Excitatory and Inhibitory Subnetworks Are Equally Selective during Decision-Making and Emerge Simultaneously during Learning. Neuron.
Applications
IF, Confocal Microscopy
(). Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set. Science
Applications
IF, Confocal Microscopy
(). Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction. PLoS Biol.
Applications
IF, Confocal Microscopy
(). The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death. J Neurosci
Applications
IF, Confocal Microscopy
(). Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature.
Applications
IF, Confocal Microscopy
(). Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis. bioRxiv
Applications
IHC, ICC, Histology
(). Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife.
Applications
IF, Confocal Microscopy
(). Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol.
Applications
IHC, ICC, Histology; Multiplex Assay
(). A psychological stressor conveyed by appetite-linked neurons. Sci Adv.
Applications
IF, Confocal Microscopy
(). Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Rep.
Applications
IF, Confocal Microscopy
(). Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution. Stem Cell Reports
Applications
IHC, ICC, Histology
(). Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell.
Applications
Undefined
(). Epigenomic state transitions characterize tumor progression in mouse lung adenocarcinoma. Cancer Cell.
Applications
IHC, ICC, Histology
(). Neural stem cells direct axon guidance via their radial fiber scaffold. Neuron.
Applications
Undefined
(). Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes. Exp Cell Res.
Applications
IF, Confocal Microscopy
(). Cycling stem cells are radioresistant and regenerate the intestine. Cell Rep.
Applications
IF, Confocal Microscopy
(). Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model. BMC Biol.
Applications
IF, Confocal Microscopy
(). Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. Elife
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol.
Applications
IF, Confocal Microscopy
(). Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun.
Applications
IF, Confocal Microscopy
(). Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas. Elife
Applications
IHC, ICC, Histology
(). Cell-type-specific gene inactivation and in situ restoration via recombinase-based flipping of targeted genomic region. J Neurosci.
Applications
IF, Confocal Microscopy
(). Neuropathophysiological significance of the c. 1449T> C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome. Biochem Biophys Res Commun.
Applications
Undefined
(). Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. J Neurosci.
Applications
Undefined
(). Adipose stromal cells enhance decellularized adipose tissue remodeling through multimodal mechanisms. Tissue Eng Part A
Applications
IHC, ICC, Histology
(). Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition. Curr Biol.
Applications
IHC, ICC, Histology
(). Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-Kv4/Shal Coupled Regulatory System. Cell Rep.
Applications
IF, Confocal Microscopy
(). A network of macrophages supports mitochondrial homeostasis in the heart. Cell.
Applications
Undefined
(). A genetically defined compartmentalized striatal direct pathway for negative reinforcement. Cell.
Applications
Undefined
(). Neural Cadherin Plays Distinct Roles for Neuronal Survival and Axon Growth under Different Regenerative Conditions. eNeuro.
Applications
IHC, ICC, Histology
(). Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants. Genome Res.
Applications
WB, IB, PCA
(). EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Struct Funct.
Applications
IF, Confocal Microscopy
(). STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol.
Applications
IHC, ICC, Histology
(). Control of orienting movements and locomotion by Projection-Defined subsets of brainstem V2a neurons. Curr Biol.
Applications
IHC, ICC, Histology
(). The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor. Oncogene.
Applications
IHC, ICC, Histology
(). A versatile system to record cell-cell interactions. Elife
Applications
WB, IB, PCA
(). Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Molecular fingerprint and developmental regulation of the tegmental GABAergic and glutamatergic neurons derived from the anterior hindbrain. Cell Rep.
Applications
IHC, ICC, Histology
(). Mapping Cell Types and Efferent Pathways in the Ascending Relaxin-3 System of the Nucleus Incertus. eNeuro.
Applications
IF, Confocal Microscopy
(). Capillary cell-type specialization in the alveolus. Nature.
Applications
IF, Confocal Microscopy
(). Salamander‐Eci: An optical clearing protocol for the three‐dimensional exploration of regeneration. Dev Dyn.
Applications
IF, Confocal Microscopy
(). HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sci Adv.
Applications
WB, IB, PCA
(). FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. Nat Cell Biol.
Applications
Undefined
(). Naturally occurring hotspot cancer mutations in Gα13 promote oncogenic signaling. J Biol Chem.
Applications
WB, IB, PCA
(). An Aurora Kinase B–Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. Front Cell Dev Biol
Applications
IF, Confocal Microscopy
(). Topographically Distinct Projection Patterns of Early-Generated and Late-Generated Projection Neurons in the Mouse Olfactory Bulb. eNeuro.
Applications
IHC, ICC, Histology
(). Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake. Nat Commun.
Applications
IHC, ICC, Histology
(). A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. Sci Adv.
Applications
IHC, ICC, Histology
(). Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction. Cell Rep Med.
Applications
IF, Confocal Microscopy
(). Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions. Nat Commun.
Applications
IHC, ICC, Histology
(). Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep.
Applications
IHC, ICC, Histology
(). Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep.
Applications
IF, Confocal Microscopy
(). Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation. Cell Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PLoS Genet.
Applications
IF, Confocal Microscopy
(). A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Ex Vivo Recording of Axonal Transport Dynamics on Postnatal Organotypic Cortical Slices. STAR Protoc.
Applications
IF, Confocal Microscopy
(). Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol.
Applications
WB, IB, PCA
(). Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol.
Applications
Undefined
(). Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation. STAR Protoc.
Applications
IF, Confocal Microscopy
(). Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells. J Bone Miner Res.
Applications
Undefined
(). Inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. J Physiol
Applications
Undefined
(). Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep.
Applications
IF, Confocal Microscopy
(). The nebulin family LIM and SH3 proteins regulate postsynaptic development and function. J Neurosci.
Applications
IF, Confocal Microscopy
(). Fruitless mutant male mosquitoes gain attraction to human odor. ELife
Applications
IF, Confocal Microscopy
(). Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis. Scientific Reports
Applications
IHC, ICC, Histology
(). In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development
Applications
IF, Confocal Microscopy
(). An evolutionarily acquired microRNA shapes development of mammalian cortical projections. Proceedings of the National Academy of Sciences of the United States of America
Applications
IHC, ICC, Histology
(). Modulation of sleep-courtship balance by nutritional status in Drosophila. ELife
Applications
IHC, ICC, Histology
(). Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation. Scientific Reports
Applications
IF, Confocal Microscopy
(). Retrograde Labeling Illuminates Distinct Topographical Organization of D1 and D2 Receptor-Positive Pyramidal Neurons in the Prefrontal Cortex of Mice. ENeuro
Applications
IHC, ICC, Histology
(). Innovations present in the primate interneuron repertoire. Nature
Applications
IHC, ICC, Histology
(). From 2D to 3D: Promising Advances in Imaging Lung Structure. Frontiers in Medicine
Applications
IF, Confocal Microscopy
(). The DMCdrive: practical 3D-printable micro-drive system for reliable chronic multi-tetrode recording and optogenetic application in freely behaving rodents. Scientific Reports
Applications
IHC, ICC, Histology
(). Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Developmental Cell
Applications
IHC, ICC, Histology
(). IDO1+ Paneth cells promote immune escape of colorectal cancer. Communications Biology
Applications
IHC, ICC, Histology
(). An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques. Neuron
Applications
IHC, ICC, Histology
(). Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron
Applications
IF, Confocal Microscopy
(). Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications
Applications
IF, Confocal Microscopy
(). TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Nature
Applications
IF, Confocal Microscopy
(). Osteoclasts Derive Predominantly from Bone Marrow-Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair. Journal of Immunology (Baltimore, Md. : 1950)
Applications
IF, Confocal Microscopy
(). Multiplexed calcium imaging of single-synapse activity and astroglial responses in the intact brain. Neuroscience Letters
Applications
IF, Confocal Microscopy
(). Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition. Protein & Cell
Applications
IF, Confocal Microscopy
(). E-cadherin is Required for the Homeostasis of Lgr5+ Gastric Antral Stem Cells. International Journal of Biological Sciences
Applications
IHC, ICC, Histology
(). In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nature Communications
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Scientific Reports
Applications
IF, Confocal Microscopy
(). Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina. Investigative Ophthalmology & Visual Science
Applications
IF, Confocal Microscopy
(). Developmental regulation of regenerative potential in Drosophila by ecdysone through a bistable loop of ZBTB transcription factors. PLOS Biology
Applications
IHC, ICC, Histology
(). Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells. Cell Communication and Signaling
Applications
WB, IB, PCA
(). Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model. Cell Death & Differentiation
Applications
IF, Confocal Microscopy
(). KCC2 overexpression prevents the paradoxical seizure-promoting action of somatic inhibition. Nature Communications
Applications
IHC, ICC, Histology
(). Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance. Front Endocrinol (Lausanne)
Applications
WB, IB, PCA
(). Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques. Front Neuroanat.
Applications
IHC, ICC, Histology
(). Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture. FASEB J.
Applications
IHC, ICC, Histology
(). CBP and p300 coactivators contribute to the maintenance of Isl1 expression by the Onecut transcription factors in embryonic spinal motor neurons. Mol Cell Neurosci.
Applications
IF, Confocal Microscopy
(). Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease. Anat Rec (Hoboken)
Applications
IHC, ICC, Histology
(). Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex. Neuron
Applications
IF, Confocal Microscopy
(). Medial Amygdala Kiss1 Neurons Mediate Female Pheromone Stimulation of Luteinizing Hormone in Male Mice. Neuroendocrinology
Applications
IHC, ICC, Histology
(). Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties. Cell Rep.
Applications
IF, Confocal Microscopy
(). Quantifying autophagic flux in kidney tissue using structured illumination microscopy. Methods Cell Biol.
Applications
IHC, ICC, Histology
(). Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus. J Neurosci.
Applications
IHC, ICC, Histology
(). Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Estrogen Regulates the Satellite Cell Compartment in Females. Cell Rep.
Applications
IF, Confocal Microscopy
(). Regional differences in mitral cell development in mouse olfactory bulb. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry. Neurobiol Dis.
Applications
IHC, ICC, Histology
(). Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res.
Applications
IF, Confocal Microscopy
(). Generation and characterization of Lhx4tdT reporter knock-in and Lhx4loxP conditional knockout mice. Genesis
Applications
IHC, ICC, Histology
(). Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Cell.
Applications
IHC, ICC, Histology
(). Genetic access to neurons in the accessory optic system reveals a role for Sema6A in midbrain circuitry mediating motion perception. J Comp Neurol.
Applications
IHC, ICC, Histology
(). Molar Bud-to-Cap Transition Is Proliferation Independent. J Dent Res.
Applications
IF, Confocal Microscopy
(). A Flower-Specific Phospholipase D Is a Stigmatic Compatibility Factor Targeted by the Self-Incompatibility Response in Brassica napus. Curr Biol.
Applications
WB, IB, PCA
(). BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell
Applications
IHC, ICC, Histology
(). Extended Flight Bouts Require Disinhibition from GABAergic Mushroom Body Neurons. Curr Biol.
Applications
IHC, ICC, Histology
(). A Non-Canonical Cortico-Amygdala Inhibitory Loop. J Neurosci.
Applications
IHC, ICC, Histology
(). Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice. PLoS One.
Applications
IF, Confocal Microscopy
(). An optimized protocol for iDISCO+ rat brain clearing, imaging, and analysis. bioRxiv
Applications
IHC, ICC, Histology
(). Hyper-diversity of CRH interneurons in mouse hippocampus. Brain Struct Funct.
Applications
IF, Confocal Microscopy
(). Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron
Applications
IF, Confocal Microscopy
(). Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. Epilepsia
Applications
IF, Confocal Microscopy
(). Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus. Curr Biol.
Applications
IHC, ICC, Histology
(). Architecture and organization of mouse posterior parietal cortex relative to extrastriate areas. Eur J Neurosci.
Applications
IF, Confocal Microscopy
(). Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells. Neuron
Applications
IHC, ICC, Histology
(). The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens. Cell Rep.
Applications
IF, Confocal Microscopy
(). Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature
Applications
IHC, ICC, Histology
(). Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. J Comp Neurol.
Applications
Array Hybridization
(). Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell.
Applications
IHC, ICC, Histology
(). Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. Cell Rep.
Applications
IHC, ICC, Histology
(). Lmx1b is required at multiple stages to build expansive serotonergic axon architectures. Elife.
Applications
IHC, ICC, Histology
(). Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward. Neuron.
Applications
IHC, ICC, Histology
(). Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell
Applications
IHC, ICC, Histology
(). Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron
Applications
IHC, ICC, Histology
(). Multiple cell types form the VIP amacrine cell population. J Comp Neurol.
Applications
IHC, ICC, Histology
(). A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion. Cell Rep.
Applications
IHC, ICC, Histology
(). Methods for renal lineage tracing: In vivo and beyond. Methods Cell Biol.
Applications
IF, Confocal Microscopy
(). Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans. Nat Neurosci.
Applications
IF, Confocal Microscopy
(). Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs. Cell Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs. Elife.
Applications
IHC, ICC, Histology
(). Sweet neurons inhibit texture discrimination by signaling TMC-expressing mechanosensitive neurons in Drosophila. Elife.
Applications
IF, Confocal Microscopy
(). Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell.
Applications
IHC, ICC, Histology
(). Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Cell Rep.
Applications
WB, IB, PCA
(). p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. Matrix Biol.
Applications
IHC, ICC, Histology
(). Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet.
Applications
Undefined
(). A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nat Commun.
Applications
LCI-S, SMART, FRET
(). Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development.
Applications
IHC, ICC, Histology
(). Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors. J Cell Sci.
Applications
IP, Co-IP
(). Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. Arthritis Res Ther.
Applications
IHC, ICC, Histology
(). Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol.
Applications
IHC, ICC, Histology
(). Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration. Stem Cell Reports.
Applications
IF, Confocal Microscopy
(). In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep.
Applications
IF, Confocal Microscopy
(). Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma. Nat Commun.
Applications
IF, Confocal Microscopy
(). GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis.
Applications
IF, Confocal Microscopy
(). Reporter lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum. Sci Rep.
Applications
IF, Confocal Microscopy
(). Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron.
Applications
IHC, ICC, Histology
(). Innovations in Primate Interneuron Repertoire. Nature
Applications
IHC, ICC, Histology
(). Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor. Cell Rep.
Applications
IF, Confocal Microscopy
(). Temporal evolution of cortical ensembles promoting remote memory retrieval. Nat Neurosci.
Applications
iDISCO
(). Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development.
Applications
IHC, ICC, Histology
(). Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep.
Applications
IF, Confocal Microscopy
(). Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors. Elife.
Applications
IHC, ICC, Histology
(). Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron
Applications
WB, IB, PCA
(). Transmission Electron Microscopy of Oligodendrocytes and Myelin. Methods Mol Biol.
Applications
Immuno-EM
(). A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells. Cell Rep.
Applications
IF, Confocal Microscopy
(). Precise Long-Range Microcircuit-to-Microcircuit Communication Connects the Frontal and Sensory Cortices in the Mammalian Brain. Neuron.
Applications
IHC, ICC, Histology
(). TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex. Nat Commun.
Applications
IHC, ICC, Histology
(). Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases. J Mol Biol.
Applications
WB, IB, PCA
(). Exocyst dynamics during vesicle tethering and fusion. Nat Commun.
Applications
WB, IB, PCA
(). Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits. Neuron.
Applications
IF, Confocal Microscopy
(). Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Rep.
Applications
IHC, ICC, Histology
(). Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues. Dev Cell.
Applications
IHC, ICC, Histology
(). A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol.
Applications
IF, Confocal Microscopy
(). Muscle-selective RUNX3 dependence of sensorimotor circuit development. Development.
Applications
IF, Confocal Microscopy
(). Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium. Nat Commun.
Applications
IHC, ICC, Histology
(). Interleukin-17 Regulates Neuron-Glial Communications, Synaptic Transmission, and Neuropathic Pain after Chemotherapy. Cell Rep.
Applications
IF, Confocal Microscopy
(). Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell.
Applications
iDISCO; IF, Confocal Microscopy
(). Microbiota imprint gut–intrinsic neuronal programming and sympathetic activity. Nature
Applications
IF, Confocal Microscopy
(). Imaging and Manipulating Pituitary Function in the Awake Mouse. Endocrinology.
Applications
IF, Confocal Microscopy
(). Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events. Cell Rep.
Applications
IHC, ICC, Histology
(). The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Dev Cell.
Applications
IHC, ICC, Histology
(). RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach. PLoS Biol.
Applications
IF, Confocal Microscopy
(). Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach. Nat Commun.
Applications
IHC, ICC, Histology
(). Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells. bioRxiv
Applications
IF, Confocal Microscopy
(). Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development.
Applications
IF, Confocal Microscopy
(). The mechanosensitive Piezo1 orchestrating angiogenesis is essential in bone fracture repair. bioRxiv
Applications
IF, Confocal Microscopy
(). Constricted migration modulates stem cell differentiation. Mol Biol Cell.
Applications
IF, Confocal Microscopy
(). Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors. JCI Insight.
Applications
IF, Confocal Microscopy
(). Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum). Nat Protoc.
Applications
IF, Confocal Microscopy
(). ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. J Cell Sci.
Applications
IF, Confocal Microscopy
(). Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells. Cancer Discov.
Applications
Immuno-EM
(). Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell.
Applications
IF, Confocal Microscopy
(). Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming. Cell Rep.
Applications
IF, Confocal Microscopy
(). Presynaptic inhibition of cutaneous afferents prevents chronic itch. Cell Rep.
Applications
IHC, ICC, Histology
(). Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development. Nat Commun.
Applications
IF, Confocal Microscopy
(). A chromosome folding intermediate at the condensin-to-cohesin transition during telophase. Nat Cell Biol.
Applications
WB, IB, PCA
(). The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits. J Neurosci.
Applications
IHC, ICC, Histology
(). A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nat Commun.
Applications
IF, Confocal Microscopy
(). Anatomical development of the cerebellothalamic tract in embryonic mice. bioRxiv
Applications
IF, Confocal Microscopy
(). Repeated hypoglycemia blunts the responsiveness of glucose-inhibited GHRH neurons by remodeling neural inputs and disrupting mitochondrial structure and function. JCI Insight.
Applications
IHC, ICC, Histology
(). Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. Neuron.
Applications
IHC, ICC, Histology
(). A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nat Neurosci.
Applications
IF, Confocal Microscopy
(). Accelerating iterative deconvolution and multiview fusion by orders of magnitude. bioRxiv
Applications
IHC, ICC, Histology
(). Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells. Dev Cell.
Applications
IHC, ICC, Histology
(). Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart. Nat Commun.
Applications
IHC, ICC, Histology
(). Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition. Elife.
Applications
IF, Confocal Microscopy
(). Spinal V3 Interneurons and Left-Right Coordination in Mammalian Locomotion. Front Cell Neurosci.
Applications
IHC, ICC, Histology
(). Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections. Methods Mol Biol.
Applications
WB, IB, PCA
(). Somatostatin-Expressing Interneurons Enable and Maintain Learning-Dependent Sequential Activation of Pyramidal Neurons. Neuron.
Applications
IF, Confocal Microscopy
(). Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports.
Applications
IF, Confocal Microscopy
(). Choice suppression through opponent but not independent function of the striatal indirect pathway. bioRxiv
Applications
IHC, ICC, Histology
(). Cell-Type-Specific D1 Dopamine Receptor Modulation of Projection Neurons and Interneurons in the Prefrontal Cortex. Cereb Cortex.
Applications
IF, Confocal Microscopy
(). Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. Cell.
Applications
IF, Confocal Microscopy
(). microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction. Cerebral Cortex
Applications
IHC, ICC, Histology
(). SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nat Commun.
Applications
WB, IB, PCA
(). The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature.
Applications
IF, Confocal Microscopy
(). Selection of an Efficient AAV Vector for Robust CNS Transgene Expression. Molecular Therapy. Methods & Clinical Development
Applications
IHC, ICC, Histology
(). Yorkie and JNK revert syncytial muscles into myoblasts during Org-1-dependent lineage reprogramming. The Journal of Cell Biology
Applications
IF, Confocal Microscopy
(). PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene
Applications
IF, Confocal Microscopy
(). Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization. Current Biology : Cb
Applications
IHC, ICC, Histology
(). Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell
Applications
IF, Confocal Microscopy
(). Sensory noise increases metacognitive efficiency. Journal of Experimental Psychology. General
Applications
Undefined
(). Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. Experimental Neurology
Applications
IHC, ICC, Histology
(). In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ. Molecular Therapy
Applications
IHC, ICC, Histology
(). Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors. Cancer Cell
Applications
FC, FACS, FLOW; IF, Confocal Microscopy; IHC, ICC, Histology; qRT-PCR, RT-PCR
(). Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition. Neuron
Applications
IF, Confocal Microscopy
(). Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner. Nature Communications
Applications
IHC, ICC, Histology
(). Two distinct mechanisms silence chinmo in Drosophila neuroblasts and neuroepithelial cells to limit their self-renewal. Development
Applications
IHC, ICC, Histology
(). A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies. Investigative Ophthalmology & Visual Science
Applications
IHC, ICC, Histology
(). Genetic targeting of Purkinje fibres by Sema3a-CreERT2. Scientific Reports
Applications
IF, Confocal Microscopy; Multiplex Assay
(). Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. The Journal of Neuroscience
Applications
WB, IB, PCA
(). An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus. Stem Cell Reports
Applications
IHC, ICC, Histology
(). Electrophysiological and Morphological Characterization of Chrna2 Cells in the Subiculum and CA1 of the Hippocampus: An Optogenetic Investigation. Frontiers in Cellular Neuroscience
Applications
IHC, ICC, Histology
(). Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. Nucleic Acids Research
Applications
IP, Co-IP; WB, IB, PCA
(). Intensify3D: Normalizing signal intensity in large heterogenic image stacks. Scientific Reports
Applications
iDISCO
(). The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors. Elife
Applications
IP, Co-IP
(). Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells. Nature Communications
Applications
IHC, ICC, Histology; ISH, FISH
(). Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nature Neuroscience
Applications
IF, Confocal Microscopy
(). Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nature Communications
Applications
IF, Confocal Microscopy
(). Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. Cell Reports
Applications
IHC, ICC, Histology
(). Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging Cell
Applications
IHC, ICC, Histology
(). Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development
Applications
IHC, ICC, Histology
(). LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. Nature Communications
Applications
WB, IB, PCA
(). A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits. Scientific Reports
Applications
IHC, ICC, Histology
(). Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. Cell
Applications
IF, Confocal Microscopy
(). Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. Aging
Applications
IF, Confocal Microscopy
(). Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. Cellular and Molecular Gastroenterology and Hepatology
Applications
IHC, ICC, Histology
(). Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice. PLOS Biology
Applications
IHC, ICC, Histology; TUNEL
(). Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration. Elife
Applications
IHC, ICC, Histology
(). Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics
Applications
WB, IB, PCA
(). Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC. Fluids and Barriers of the CNS
Applications
IF, Confocal Microscopy
(). Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake. Cell Metabolism
Applications
IHC, ICC, Histology; ISH, FISH
(). Intersectional Strategies for Targeting Amacrine and Ganglion Cell Types in the Mouse Retina. Frontiers in Neural Circuits
Applications
IHC, ICC, Histology
(). Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. Scientific Reports
Applications
IHC, ICC, Histology
(). Communication from Learned to Innate Olfactory Processing Centers Is Required for Memory Retrieval in Drosophila. Neuron
Applications
IF, Confocal Microscopy
(). Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyte heterogeneity. PLOS Biology
Applications
IHC, ICC, Histology
(). miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells
Applications
IF, Confocal Microscopy
(). Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations. Communications Biology
Applications
IHC, ICC, Histology
(). In utero CRISPR-mediated therapeutic editing of metabolic genes. Nature Medicine
Applications
IF, Confocal Microscopy
(). Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication. Cell Reports
Applications
IF, Confocal Microscopy
(). A complex peripheral code for salt taste in Drosophila. Elife
Applications
IHC, ICC, Histology; Multiplex Assay
(). Probing aggrephagy using chemically-induced protein aggregates. Nature Communications
Applications
IP, Co-IP
(). A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nature Communications
Applications
LCI-S, SMART, FRET
(). Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses. Journal of Clinical Investigation
Applications
IF, Confocal Microscopy
(). Exocyst dynamics during vesicle tethering and fusion. Nature Communications
Applications
WB, IB, PCA
(). Profiling proliferative cells and their progeny in damaged murine hearts. Proc. Natl. Acad. Sci. U.S.A
Applications
IF, Confocal Microscopy
(). Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1. Cell Reports
Applications
IF, Confocal Microscopy
(). OCRL Deficiency Impairs Endolysosomal Function in a Humanized Mouse Model for Lowe Syndrome and Dent Disease. Human Molecular Genetics
Applications
IF, Confocal Microscopy
(). Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. Journal of Clinical Investigation
Applications
IHC, ICC, Histology
(). The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion. Molecular Biology of the Cell
Applications
WB, IB, PCA
(). Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex. Frontiers in Cellular Neuroscience
Applications
IF, Confocal Microscopy; Multiplex Assay
(). Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues. Molecular Metabolism
Applications
IF, Confocal Microscopy
(). The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human Mutation
Applications
WB, IB, PCA
(). Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2. Frontiers in Cellular Neuroscience
Applications
IHC, ICC, Histology
(). Optical Approaches for Interrogating Neural Circuits Controlling Hormone Secretion. Endocrinology
Applications
IHC, ICC, Histology
(). Thalamostriatal and cerebellothalamic pathways in a songbird, the Bengalese finch. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Genetic lineage tracing analysis of c-kit+ stem/progenitor cells revealed a contribution to vascular injury-induced neointimal lesions. J Mol Cell Cardiol.
Applications
IF, Confocal Microscopy
(). Limited Regeneration of Adult Salivary Glands after Severe Injury Involves Cellular Plasticity. Cell Rep.
Applications
IHC, ICC, Histology
(). Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction. Biochem Biophys Res Commun.
Applications
IHC, ICC, Histology
(). Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains. Brain Struct Funct.
Applications
IHC, ICC, Histology
(). Reconstruction of the Human Colon Epithelium In Vivo. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis. Cell Rep.
Applications
IF, Confocal Microscopy
(). Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov.
Applications
WB, IB, PCA; IF, Confocal Microscopy
(). A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development
Applications
WB, IB, PCA; IF, Confocal Microscopy
(). Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cereb Cortex.
Applications
IHC, ICC, Histology
(). KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity
Applications
FC, FACS, FLOW
(). Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea. Eur J Neurosci.
Applications
IF, Confocal Microscopy
(). Genetic dissection of the neuro-glio-vascular machinery in the adult brain. Mol Brain.
Applications
IHC, ICC, Histology
(). Genetic Targeting of Organ-Specific Blood Vessels. Circ Res.
Applications
IF, Confocal Microscopy
(). A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Rep.
Applications
IHC, ICC, Histology
(). Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells. FASEB J.
Applications
IHC, ICC, Histology
(). Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication. Curr Biol.
Applications
IF, Confocal Microscopy
(). The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron
Applications
IF, Confocal Microscopy
(). Parallel Arousal Pathways in the Lateral Hypothalamus. eNeuro
Applications
IHC, ICC, Histology
(). Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Curr Biol.
Applications
IF, Confocal Microscopy
(). An Optical Neuron-Astrocyte Proximity Assay at Synaptic Distance Scales. Neuron
Applications
IHC, ICC, Histology
(). Neuronal connections of the central amygdalar nucleus with refeeding-activated brain areas in rats. Brain Struct Funct.
Applications
IF, Confocal Microscopy
(). A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons. Neuron
Applications
IF, Confocal Microscopy
(). A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period. Neuron
Applications
IF, Confocal Microscopy
(). Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors. Cell Rep.
Applications
WB, IB, PCA
(). Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior. Neuron
Applications
IHC, ICC, Histology
(). Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metab.
Applications
IHC, ICC, Histology
(). A circuit from hippocampal CA2 to lateral septum disinhibits social aggression. Nature.
Applications
IHC, ICC, Histology
(). A synaptic threshold mechanism for computing escape decisions. Nature
Applications
IHC, ICC, Histology
(). Genetic lineage tracing of resident stem cells by DeaLT. Nat Protoc.
Applications
IF, Confocal Microscopy
(). Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med.
Applications
IF, Confocal Microscopy
(). Visual Projection Neurons Mediating Directed Courtship in Drosophila. Cell.
Applications
IF, Confocal Microscopy