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RFP Antibody Pre-adsorbed
Rabbit Polyclonal
600-401-379S
600-401-379
25 µL
100 µg
ELISA, IF, IHC, WB, EM, FC, FISH, IP, Other
RFP, rRFP, tdTomato
Rabbit
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Availability: Ships next business day
Availability: Ships next business day
Shipping info:
$50.00 to US & Canada for most products. Final costs are calculated at checkout.
Description
Background
Fluorescent proteins such as Discosoma Red Fluorescent Protein (DsRed) from sea anemone Discosoma sp. mushroom or green fluorescent protein (GFP) from Aequorea victoria jellyfish are widely used in research practice. Fusion RFP and GFP commonly serve as marker for gene expression and protein localization. As DsRed and GFP share only 19% identity, therefore, in general, anti-GFP antibodies do not recognize DsRed protein and vice versa. Structurally, Discosoma red fluorescent protein is similar to Aequorea green fluorescent protein in terms of its overall fold (a β-can) and chromophore-formation chemistry. However, Discosoma red fluorescent protein undergoes an additional step in the chromophore maturation and obligates tetrameric structure. Rockland offers many controls, monoclonal, and polyclonal antibodies for RFP.
Application Note
Polyclonal anti-RFP is designed to detect RFP and its variants. This antibody has been tested by ELISA, western blot, IF, and IHC, and is suitable for use in IP, ICC, dual RNA-FISH, iDISCO+, IEM, and FLOW. This antibody can be used to detect RFP by ELISA (sandwich or capture) for the direct binding of antigen. Biotin conjugated polyclonal anti-RFP used in a sandwich ELISA with unconjugated anti-RFP is well suited to titrate RFP in solution. The detection antibody conjugated to biotin is subsequently reacted with streptavidin conjugated HRP (code # S000-03). Fluorochrome conjugated polyclonal anti-RFP can be used to detect RFP by immunofluorescence microscopy in cell expression systems and can detect RFP containing inserts. Significant amplification of signal is achieved using fluorochrome conjugated polyclonal anti-RFP relative to the fluorescence of RFP alone. For immunoblotting use either alkaline phosphatase or peroxidase conjugated polyclonal anti-RFP to detect RFP or RFP containing proteins on western blots. Optimal titers for applications should be determined by the researcher.
Purity/Specificity
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Red Fluorescent Protein (Discosoma) coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Expect reactivity against RFP and its variants: mCherry, tdTomato, mBanana, mOrange, mPlum, mOrange and mStrawberry. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum and purified and partially purified Red Fluorescent Protein (Discosoma). No reaction was observed against Human, Mouse or Rat serum proteins.
Anti-RFP (RABBIT) Antibody Min X Hu Ms and Rt Serum Proteins - 600-401-379
rabbit anti-RFP antibody, DsRed, rDsRed, Discosoma sp. Red Fluorescent Protein, Red fluorescent protein drFP583.
DsRed
ELISA, IF, IHC, WB
EM, FC, FISH, IP, Other
RFP, rRFP, tdTomato
Rabbit
RFP
Polyclonal
IgG
Recombinant Protein
The immunogen is a Red Fluorescent Protein (RFP) fusion protein corresponding to the full length amino acid sequence (234aa) derived from the mushroom polyp coral Discosoma.
Liquid (sterile filtered)
1.05mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Zhang C et al. A brainstem circuit for nausea suppression. Cell Rep. (2022)
Applications
IHC, ICC, Histology
Shao YQ et al. A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus. Curr Biol. (2022)
Applications
Undefined
Twarkowski H et al. A dentate gyrusdentate gyrus-CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. Elife. (2022)
Applications
IHC, ICC, Histology
Kanada M et al. A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles. Pharmaceutics. (2022)
Applications
WB, IB, PCA
Leopold AV et al. A general approach for engineering RTKs optically controlled with far-red light. Nat Methods. (2022)
Applications
Undefined
Cho KF et al. A light-gated transcriptional recorder for detecting cell-cell contacts. Elife. (2022)
Applications
IF, Confocal Microscopy
Wang H et al. A novel spinal neuron connection for heat sensation. Neuron. (2022)
Applications
Undefined
Sorrells TR et al. A persistent behavioral state enables sustained predation of humans by mosquitoes. Elife. (2022)
Applications
IF, Confocal Microscopy
Briquet M et al. Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. J Cereb Blood Flow Metab. (2022)
Applications
IHC, ICC, Histology
Godfrey N et al. Activation of LH GABAergic inputs counteracts fasting‐induced changes in tVTA/RMTG neurons. J Physiol. (2022)
Applications
Undefined
Chen C et al. Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion. Front Pharmacol. (2022)
Applications
IHC, ICC, Histology
Zhang KY et al. Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture. STAR Protoc. (2022)
Applications
IF, Confocal Microscopy
Henriques VJ et al. Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells. (2022)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Henriques VJ et al. Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells. (2022)
Applications
IHC, ICC, Histology
Yang X et al. Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells. J Cereb Blood Flow Metab. (2022)
Applications
Undefined
Zhou K et al. CENP-N promotes the compaction of centromeric chromatin. Nat Struct Mol Biol. (2022)
Applications
IF, Confocal Microscopy
Yousefi M et al. Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer Res. (2022)
Applications
IHC, ICC, Histology
Yoshinaga S et al. Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate. Neurosci Res. (2022)
Applications
Undefined
Qu R et al. Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. (2022)
Applications
Undefined
Ademi H et al. Deciphering the origins and fates of steroidogenic lineages in the mouse testis. Cell Rep. (2022)
Applications
IF, Confocal Microscopy
Liu Z et al. Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction. Nat Commun. (2022)
Applications
IHC, ICC, Histology
Canton-Josh JE et al. Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells. Elife. (2022)
Applications
IHC, ICC, Histology
Wang H et al. Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo. J Biol Chem. (2022)
Applications
IF, Confocal Microscopy
Park HH et al. Dual-functional hydrogel system for spinal cord regeneration with sustained release of arylsulfatase B alleviates fibrotic microenvironment and promotes axonal regeneration. Biomaterials. (2022)
Applications
IHC, ICC, Histology
Eroglu E et al. Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders. Nat Cell Biol. (2022)
Applications
IF, Confocal Microscopy
Doss SV et al. Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice. Front Cell Dev Biol. (2022)
Applications
WB, IB, PCA
Li X et al. Generation of Piezo1‐CreER transgenic mice for visualization and lineage tracing of mechanical force responsive cells in vivo. Genesis. (2022)
Applications
Undefined
Deng M et al. Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis. Cell Res. (2022)
Applications
Undefined
Liu K et al. Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. J Cell Biol. (2022)
Applications
Undefined
Li Z et al. Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. Elife. (2022)
Applications
IF, Confocal Microscopy
Metcalfe M et al. Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury. Exp Neurol. (2022)
Applications
IF, Confocal Microscopy
Chen, Y et al. Club cells employ regeneration mechanisms during lung tumorigenesis. Nature Communications (2022)
Applications
IF, Confocal Microscopy
Kakava-Georgiadou, N et al. Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus. Scientific Reports (2022)
Applications
IF, Confocal Microscopy
Kosillo, P et al. Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2. ELife (2022)
Applications
Light-Sheet Microscopy (LSM); Other
Silva, MSB et al. Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway. Proceedings of the National Academy of Sciences of the United States of America (2022)
Applications
IHC, ICC, Histology
Tang, Y et al. PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis. International Journal of Biological Sciences (2022)
Applications
IHC, ICC, Histology
Hu, B et al. Origin and function of activated fibroblast states during zebrafish heart regeneration. Nature Genetics (2022)
Applications
IF, Confocal Microscopy
Taketomi, T et al. Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability. Scientific Reports (2022)
Applications
IF, Confocal Microscopy
Talsma, AD et al. The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration. Journal of Neuroinflammation (2022)
Applications
IF, Confocal Microscopy
Lefler, JE et al. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Science Alliance (2022)
Applications
IF, Confocal Microscopy
Xu, J et al. Intersectional mapping of multi-transmitter neurons and other cell types in the brain. Cell Reports (2022)
Applications
IHC, ICC, Histology
Katreddi, RR et al. Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents. Development (Cambridge, England) (2022)
Applications
IF, Confocal Microscopy
Hill, RZ et al. PIEZO1 transduces mechanical itch in mice. Nature (2022)
Applications
IHC, ICC, Histology
Asencor, AI et al. Selectively Imaging Cranial Sensory Ganglion Neurons Using AAV-PHP.S. ENeuro (2022)
Applications
IHC, ICC, Histology
Noristani, HN et al. Co-targeting B-RAF and PTEN Enables Sensory Axons to Regenerate Across and Beyond the Spinal Cord Injury. Frontiers in Molecular Neuroscience (2022)
Applications
IHC, ICC, Histology
Leystra, AA et al. Multi-ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy. Cancer Reports (Hoboken, N.J.) (2022)
Applications
IHC, ICC, Histology
Catela, C et al. Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. ELife (2022)
Applications
IF, Confocal Microscopy
Donnelly, CR et al. Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition. Cell and Tissue Research (2022)
Applications
IF, Confocal Microscopy
Lotsberg ML et al. Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. Front Oncol. (2022)
Applications
IF, Confocal Microscopy
Lecoin L et al. Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun. (2022)
Applications
IHC, ICC, Histology
Allen A et al. Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses. Int J Mol Sci. (2022)
Applications
WB, IB, PCA
Xue Y et al. Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth. Sci Adv. (2022)
Applications
IF, Confocal Microscopy
Nguyen E et al. Medullary kappa-opioid receptor neurons inhibit pain and itch through a descending circuit. Brain. (2022)
Applications
Undefined
Tanasic D et al. Myosin V facilitates polarised E‐cadherin secretion. Traffic. (2022)
Applications
IHC, ICC, Histology
Steinecke A et al. Neuromodulatory control of inhibitory network arborization in the developing postnatal neocortex. Sci Adv. (2022)
Applications
IHC, ICC, Histology
Roome RB. Netrin1 and reelin signaling are required for the migration of anterolateral system neurons in the embryonic spinal cord. Pain. (2022)
Applications
Undefined
Vignoli B et al. Perirhinal Cortex LTP Does Not Require Astrocyte BDNF-TrkB Signaling. Cells. (2022)
Applications
IHC, ICC, Histology
Hanini-Daoud M et al. Processing of information from the parafascicular nucleus of the thalamus through the basal ganglia. J Neurosci Res. (2022)
Applications
IF, Confocal Microscopy
Li Z et al. Postnatal state transition of cardiomyocyte as a primary step in heart maturation. Protein Cell. (2022)
Applications
IF, Confocal Microscopy
Zeziulia M et al. Proton-gated anion transport governs macropinosome shrinkage. Nat Cell Biol. (2022)
Applications
IF, Confocal Microscopy
Gaultier C et al. Regulation of developmental hierarchy in Drosophila neural stem cell tumors by COMPASS and Polycomb complexes. Sci Adv. (2022)
Applications
IF, Confocal Microscopy
Zhang KL et al. Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity. Elife. (2022)
Applications
IHC, ICC, Histology
Wu Y et al. Robust and sensitive in situ RNA detection using Yn-situ. Cell Rep Methods. (2022)
Applications
IF, Confocal Microscopy
Szczurkowska J et al. Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development. Cell Rep. (2022)
Applications
IF, Confocal Microscopy
Bourhy L et al. Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours. Brain. (2022)
Applications
IHC, ICC, Histology
Wang LH et al. Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nat Neurosci. (2022)
Applications
Undefined
Bali N et al. Sticks and Stones, a conserved cell surface ligand for the Type IIa RPTP Lar, regulates neural circuit wiring in Drosophila. Elife. (2022)
Applications
IHC, ICC, Histology
Ramos R et al. Strong Aversive Conditioning Triggers a Long-Lasting Generalized Aversion. Front Cell Neurosci. (2022)
Applications
IHC, ICC, Histology
Hobson BD et al. Subcellular proteomics of dopamine neurons in the mouse brain. Elife. (2022)
Applications
IHC, ICC, Histology
Leinonen JV et al. Structural and Functional Support by Left Atrial Appendage Transplant to the Left Ventricle after a Myocardial Infarction. Int J Mol Sci. (2022)
Applications
iDISCO
Smit MJ et al. The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity. J Cell Sci. (2022)
Applications
IF, Confocal Microscopy
d'Andrea FB et al. The essential M. tuberculosis Clp protease is functionally asymmetric in vivo. Sci Adv. (2022)
Applications
WB, IB, PCA
Scott EP et al. The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia. (2022)
Applications
IHC, ICC, Histology
Zhang Y et al. Targeting thalamic circuits rescues motor and mood deficits in PD mice. Nature. (2022)
Applications
Undefined
Guo N et al. Transcriptional regulation of neural stem cell expansion in the adult hippocampus. Elife. (2022)
Applications
ISH, FISH
Crist SB et al. Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nat Cell Biol. (2022)
Applications
Undefined
Evers MJW et al. Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles. J Control Release. (2022)
Applications
IHC, ICC, Histology
Hilton BJ et al. An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury. Neuron. (2022)
Applications
IHC, ICC, Histology
Engmann AK et al. Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Nat Protoc. (2022)
Applications
Undefined
Lambert E et al. The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. Acta Neuropathol Commun. (2022)
Applications
IHC, ICC, Histology
Dahl SL et al. Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality. Acta Physiol (Oxf). (2022)
Applications
ISH, FISH
Pei Y et al. Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs. Chem Phys Lipids. (2022)
Applications
Undefined
Leary N et al. Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes. J Extracell Vesicles. (2022)
Applications
IF, Confocal Microscopy
Wong BH et al. The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis. J Biol Chem. (2022)
Applications
IHC, ICC, Histology
Ohara TE et al. Adaptive differentiation promotes intestinal villus recovery. Dev Cell. (2022)
Applications
Undefined
Koffman EE et al. Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses. JCI Insight. (2022)
Applications
IHC, ICC, Histology
Amorim A et al. IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation. Nat Immunol. (2022)
Applications
Undefined
Ang PS et al. The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development (2022)
Applications
IF, Confocal Microscopy
Yeh CH et al. Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells. Immunity. (2022)
Applications
Undefined
Ramirez S et al. Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab. (2022)
Applications
IF, Confocal Microscopy
Yan R et al. SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport. Dev Cell. (2022)
Applications
Undefined
McMurray KM et al. Subfornical organ interleukin 1 receptor: a novel regulator of spontaneous and conditioned fear associated behaviors in mice. Brain Behav Immun. (2022)
Applications
IHC, ICC, Histology
Maeoka Y et al. Combined Kelch-Like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice. J Am Soc Nephrol. (2022)
Applications
Undefined
Hobson BD et al. Subcellular and regional localization of mRNA translation in midbrain dopamine neurons. Cell Rep. (2022)
Applications
IHC, ICC, Histology
Rose M et al. Twist regulates Yorkie activity to guide lineage reprogramming of syncytial alary muscles. Cell Rep. (2022)
Applications
IF, Confocal Microscopy
Song X et al. Genome Editing with AAV-BR1-CRISPR in Postnatal Mouse Brain Endothelial Cells. Int J Biol Sci. (2022)
Applications
IHC, ICC, Histology
Prochazkova K et al. Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei. Nucleic Acids Res. (2022)
Applications
IP, Co-IP; ISH, FISH
Chaves T et al. Median raphe region GABAergic neurons contribute to social interest in mouse. Life Sci. (2022)
Applications
IHC, ICC, Histology
Sarrafha L et al. High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells. STAR Protoc. (2022)
Applications
IF, Confocal Microscopy
Liang SQ et al. AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Molecular Therapy (2022)
Applications
IF, Confocal Microscopy
Boyd P et al. Iron contributes to photoreceptor degeneration and Müller glia proliferation in the zebrafish light-treated retina. Exp Eye Res. (2022)
Applications
Undefined
Hunt MA et al. DRGquant: A new modular AI-based Pipeline for 3D Analysis of the DRG. J Neurosci Methods. (2022)
Applications
IHC, ICC, Histology
Devireddy S et al. Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo. J Cell Biol. (2022)
Applications
Undefined
Lavalou J et al. Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry. Dev Cell. (2021)
Applications
IF, Confocal Microscopy
Anirudh A et al. Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel. Frontiers in Neuroscience (2021)
Applications
IHC, ICC, Histology
Jerez D et al. A deep learning approach to identifying immunogold particles in electron microscopy images. Scientific Reports (2021)
Applications
Immuno-EM
Butt UJ et al. CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge. International Journal of Molecular Sciences (2021)
Applications
Other
Jin S et al. Drp1 is required for AgRP neuronal activity and feeding. ELife (2021)
Applications
Immuno-EM
Min S et al. Control of feeding by Piezo-mediated gut mechanosensation in Drosophila. ELife (2021)
Applications
IHC, ICC, Histology
Hu S et al. Widespread labeling and genomic editing of the fetal central nervous system by in utero CRISPR AAV9-PHP.eB administration. Development (Cambridge, England) (2021)
Applications
IHC, ICC, Histology
Kinoshita M et al. Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell (2021)
Applications
IF, Confocal Microscopy
Ma T et al. Decoding neuronal composition and ontogeny of individual hypothalamic nuclei. Neuron. (2021)
Applications
Undefined
Hara A et al. Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity. Genes Cells. (2021)
Applications
IF, Confocal Microscopy
Canhos LL et al. Repetitive injury and absence of monocytes promote astrocyte self‐renewal and neurological recovery. Glia. (2021)
Applications
IHC, ICC, Histology
Hafner G et al. Increased Callosal Connectivity in Reeler Mice Revealed by Brain-Wide Input Mapping of VIP Neurons in Barrel Cortex. Cereb Cortex. (2021)
Applications
ISH, FISH
Reitz SL et al. Activation of preoptic tachykinin 1 neurons promotes wakefulness over sleep and volatile anesthetic-induced unconsciousness. Curr Biol. (2021)
Applications
IHC, ICC, Histology
Russo GL et al. CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell. (2021)
Applications
IF, Confocal Microscopy
Russo GL et al. CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell. (2021)
Applications
WB, IB, PCA
Kasashima H et al. Stromal SOX2 upregulation promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population. Dev Cell. (2021)
Applications
Undefined
Zhang C et al. Area postrema cell types that mediate nausea-associated behaviors. Neuron. (2021)
Applications
Undefined
Zhang KY et al. Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells. Stem Cell Reports (2021)
Applications
Undefined
Tan SH et al. A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Andersen DB et al. Using a reporter mouse to map known and novel sites of GLP-1 receptor expression in peripheral tissues of male mice. Endocrinology. (2021)
Applications
Undefined
Stahley SN et al. Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. Elife (2021)
Applications
WB, IB, PCA
Murray-Nerger LA et al. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res (2021)
Applications
WB, IB, PCA
Jiang Z et al. PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat. Cell Rep. (2021)
Applications
IF, Confocal Microscopy
Nguyen E et al. Morphine acts on spinal dynorphin neurons to cause itch through disinhibition. Sci Transl Med. (2021)
Applications
Undefined
Zheng XT et al. Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex. Nat Commun. (2021)
Applications
WB, IB, PCA
Butt UJ et al. Hippocampal neurons respond to brain activity with functional hypoxia. Mol Psychiatry. (2021)
Applications
IF, Confocal Microscopy
Han X et al. A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. (2021)
Applications
Undefined
Hou Y et al. Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Lowenstein ED et al. Olig3 regulates early cerebellar development. Elife (2021)
Applications
IF, Confocal Microscopy
Tomita H et al. Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas. Cell Rep. (2021)
Applications
IF, Confocal Microscopy
Dawson CA et al. Intravital microscopy of dynamic single-cell behavior in mouse mammary tissue. Nat Protoc. (2021)
Applications
Undefined
Abbassi L et al. Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation. Nat Commun. (2021)
Applications
IF, Confocal Microscopy
Suzanne van der Veldt et al. Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum. PLoS Biol. (2021)
Applications
IHC, ICC, Histology
Ngo, MT et al. Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior. Advanced Functional Materials (2021)
Applications
IHC, ICC, Histology
Wilson, MM et al. An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis. Science Advances (2021)
Applications
WB, IB, PCA
Perry, J et al. Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model. Cells (2021)
Applications
IHC, ICC, Histology
Vaccari Cardoso, B et al. Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release. Brain Sciences (2021)
Applications
IHC, ICC, Histology
Benthall, KN et al. Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning. Cell Reports (2021)
Applications
IHC, ICC, Histology
Hatori, R et al. Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling. ELife (2021)
Applications
IF, Confocal Microscopy
Guarascio, DM et al. Functional expression of TMEM16A in taste bud cells. The Journal of Physiology (2021)
Applications
IHC, ICC, Histology
Koike, H et al. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature Protocols (2021)
Applications
IF, Confocal Microscopy
Harris, JM et al. Optogenetic axon guidance in embryonic zebrafish. Star Protocols (2021)
Applications
IHC, ICC, Histology
Zhang W et al. The bone microenvironment invigorates metastatic seeds for further dissemination. Cell. (2021)
Applications
IF, Confocal Microscopy
Garcia-Marcos M. Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators. Elife. (2021)
Applications
WB, IB, PCA
Hoffmann HM et al. The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. J Neurosci Res. (2021)
Applications
Undefined
Zhang YH et al. Cascade diversification directs generation of neuronal diversity in the hypothalamus. Cell Stem Cell. (2021)
Applications
IHC, ICC, Histology
Viventi S et al. In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia. Stem Cells Transl Med. (2021)
Applications
IF, Confocal Microscopy
Kamitakahara AK. et al. MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development. Front Neurosci. (2021)
Applications
IF, Confocal Microscopy
Flanagan DJ et al. NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature. (2021)
Applications
Undefined
Snas-Dublanc A et al. Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors. Neuron. (2021)
Applications
Undefined
Wu M et al. Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions. Elife. (2021)
Applications
IHC, ICC, Histology
Ji W wt al. Analysis of growth cone extension in standardized coordinates highlights self-organization rules during wiring of the Drosophila visual system. PLoS Genet. (2021)
Applications
IHC, ICC, Histology
Scekic-Zahirovic J. et al. Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism. Prog Neurobiol. (2021)
Applications
IF, Confocal Microscopy
Huang S et al. Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell. (2021)
Applications
Undefined
Guillen-Samander A et al. VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol. (2021)
Applications
IF, Confocal Microscopy
Guillen-Samander A et al. VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol. (2021)
Applications
WB, IB, PCA
Campbell LA et al. Protein-retention expansion microscopy for visualizing subcellular organelles in fixed brain tissue. J Neurosci Methods. (2021)
Applications
IHC, ICC, Histology
Paterno R et al. Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Ye Q et al. SARS-CoV-2 infection in the mouse olfactory system. Cell Discov. (2021)
Applications
IF, Confocal Microscopy
Baltruchat L et al. Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Deng H et al. A genetically defined insula-brainstem circuit selectively controls motivational vigor. Cell. (2021)
Applications
Undefined
Shen Z et al. Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Dorst MC et al. Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proc Natl Acad Sci USA (2021)
Applications
IHC, ICC, Histology
Matho KS et al. Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature. (2021)
Applications
IF, Confocal Microscopy
Li J et al. The Coiled‐Coil Forming Peptide (KVSALKE)5 Is a Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Adv Healthc Mater. (2021)
Applications
Undefined
Childs BG et al. Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis. Nat Aging. (2021)
Applications
IF, Confocal Microscopy; TUNEL
Redder E et al. Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities. PLoS One (2021)
Applications
IF, Confocal Microscopy
Chen P et al. Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair. Cell Calcium. (2021)
Applications
Undefined
Jin H et al. Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. Nat Commun. (2021)
Applications
IF, Confocal Microscopy
Wang H et al. Inactivation of Hedgehog signal transduction in adult astrocytes results in region-specific blood–brain barrier defects. Proc Natl Acad Sci USA (2021)
Applications
IHC, ICC, Histology
Rudnick JA et al. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev. (2021)
Applications
IHC, ICC, Histology
Ressler RL et al. Covert capture and attenuation of a hippocampus-dependent fear memory. Nat Neurosci. (2021)
Applications
IHC, ICC, Histology
Helseth AR et al. Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice. Science. (2021)
Applications
IHC, ICC, Histology
Dalghi MG et al. Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI Insight. (2021)
Applications
IF, Confocal Microscopy
Nagai J et al. Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron. (2021)
Applications
IHC, ICC, Histology
Moser C et al. Quantification of adipocyte numbers following adipose tissue remodeling. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Bernau K et al. Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. (2021)
Applications
Undefined
Lancaster CE et al. Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes. J Cell Biol. (2021)
Applications
Undefined
Ma W et al. Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma. Nat Cancer. (2021)
Applications
Undefined
Liu X et al. Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. Nat Commun. (2021)
Applications
IF, Confocal Microscopy
Fazilaty H et al. Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep. (2021)
Applications
IF, Confocal Microscopy
Barthet VJA et al. Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Sci Adv. (2021)
Applications
IHC, ICC, Histology
Taranda J et al. Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Lentini C et al. Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell Stem Cell. (2021)
Applications
IHC, ICC, Histology
Xie T et al. Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis. Sci Adv. (2021)
Applications
IHC, ICC, Histology
Hayano Y et al. IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Sci Adv. (2021)
Applications
IHC, ICC, Histology
Hou S et al. Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory. Sci Immunol. (2021)
Applications
Undefined
Wu CY et al. Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production. iScience. (2021)
Applications
IF, Confocal Microscopy
Nestor-Kalinoski A et al. Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol. (2021)
Applications
IF, Confocal Microscopy
Nestor-Kalinoski A et al. Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol. (2021)
Applications
IHC, ICC, Histology
Bado IL et al. The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. Dev Cell. (2021)
Applications
Undefined
Freed-Pastor WA et al. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. (2021)
Applications
Undefined
Pace JA et al. Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv. (2021)
Applications
IF, Confocal Microscopy
Takatoh J et al. Constructing an adult orofacial premotor atlas in Allen mouse CCF. Elife (2021)
Applications
IHC, ICC, Histology
Makhmutova M et al. Pancreatic β-cells communicate with vagal sensory neurons. Gastroenterology (2021)
Applications
Undefined
Li J et al. Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metab. (2021)
Applications
Undefined
Reuther P et al. Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. J Exp Med. (2021)
Applications
Undefined
Choi EB et al. ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain. Sci Adv. (2021)
Applications
IF, Confocal Microscopy
Garcia MT et al. Transcriptional profiling of sequentially generated septal neuron fates. Elife. (2021)
Applications
IF, Confocal Microscopy
Ichinose M et al. The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development (2021)
Applications
IHC, ICC, Histology; Other
Chen X et al. Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states. Sci Rep. (2021)
Applications
IHC, ICC, Histology
Baldwin KT et al. HepaCAM controls astrocyte self-organization and coupling. Neuron. (2021)
Applications
Undefined
Flowers BM et al. Cell of origin influences pancreatic cancer subtype. Cancer Discov. (2021)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Ohlig S et al. Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4. EMBO J. (2021)
Applications
IHC, ICC, Histology
Liu X et al. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. (2021)
Applications
IF, Confocal Microscopy
Fatehullah A et al. A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers. Nat Cell Biol. (2021)
Applications
Undefined
Zewdu R et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife. (2021)
Applications
IHC, ICC, Histology
Gschwend J et al. Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. J Exp Med. (2021)
Applications
IF, Confocal Microscopy
Leroy F et al. Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Phychiatry. (2021)
Applications
Undefined
Ghilas S et al. Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells. iScience. (2021)
Applications
IF, Confocal Microscopy
Sahni V et al. Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting. Cell Rep. (2021)
Applications
IHC, ICC, Histology; Other
Zhang X et al. Genetically identified amygdala–striatal circuits for valence-specific behaviors. Nat Neurosci. (2021)
Applications
Undefined
Dong A et al. A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol. (2021)
Applications
IHC, ICC, Histology
Dong A et al. A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol. (2021)
Applications
Undefined
Salewski K et al. Ronin governs the metabolic capacity of the embryonic lineage for post‐implantation development. EMBO Reports (2021)
Applications
IF, Confocal Microscopy
Logiacco F et al. Microglia sense neuronal activity via GABA in the early postnatal hippocampus. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Kiourtis C et al. Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biol Open (2021)
Applications
IF, Confocal Microscopy
Surbhi et al. Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Mol Metab. (2021)
Applications
IF, Confocal Microscopy
Kemp Jr JP et al. Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes. Mol Biol Cell. (2021)
Applications
IF, Confocal Microscopy
Buddika K et al. I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. Development (2021)
Applications
IF, Confocal Microscopy
Onori MP et al. RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. PLoS Biol. (2021)
Applications
IHC, ICC, Histology
Shin B et al. Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice. Endocrinology (2021)
Applications
Undefined
O'Neil SD et al. Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. Elife. (2021)
Applications
IHC, ICC, Histology
Beekhof GC et al. Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors. Elife. (2021)
Applications
IHC, ICC, Histology
Dias DO et al. Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. Nat Commun. (2021)
Applications
IHC, ICC, Histology
Fiederling F et al. Tools for efficient analysis of neurons in a 3D reference atlas of whole mouse spinal cord. Cell Rep Methods. (2021)
Applications
IHC, ICC, Histology
Nagappan S et al. Parallel processing by distinct classes of principal neurons in the olfactory cortex. Elife. (2021)
Applications
IHC, ICC, Histology
Casellas-Diaz S et al. Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development. EMBO Rep. (2021)
Applications
WB, IB, PCA
Sahni V et al. Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Cell Rep. (2021)
Applications
IHC, ICC, Histology; Other
Vignoli B et al. Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention. Commun Biol. (2021)
Applications
IHC, ICC, Histology
Zhang S et al. Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. Circulation. (2021)
Applications
IF, Confocal Microscopy
Biehler C et al. Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex. Elife. (2021)
Applications
IF, Confocal Microscopy
Ferreira-Pinto MJ et al. Functional diversity for body actions in the mesencephalic locomotor region. Cell. (2021)
Applications
IHC, ICC, Histology
Hawkins FJ et al. Derivation of airway basal stem cells from human pluripotent stem cells. Cell Stem Cell. (2021)
Applications
IF, Confocal Microscopy
Kim D et al. Identifying oligodendrocyte enhancers governing Plp1 expression. Hum Mol Genet. (2021)
Applications
IF, Confocal Microscopy
Kempf J et al. Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Roy DS et al. Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron. (2021)
Applications
Undefined
Mitsogiannis MD et al. Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. (2021)
Applications
IHC, ICC, Histology
Lin TY et al. Fibroblast dedifferentiation as a determinant of successful regeneration. Dev Cell. (2021)
Applications
IF, Confocal Microscopy
de Kloet SF et al. Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum. Nat Commun. (2021)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Bruzsik B et al. Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli. Neurobiol Stress. (2021)
Applications
IHC, ICC, Histology
Shyam R et al. Mitochondrial ROS induced lysosomal dysfunction and autophagy impairment in an animal model of congenital hereditary endothelial dystrophy. Invest Ophthalmol Vis Sci. (2021)
Applications
IHC, ICC, Histology
Hernandez-Clavijo A et al. TMEM16A and TMEM16B modulate pheromone-evoked action potential firing in mouse vomeronasal sensory neurons. eNeuro. (2021)
Applications
IHC, ICC, Histology
Matsuki T et al. STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. J Neurosci (2021)
Applications
Undefined
Sato R et al. TGFβ signaling activated by cancer-associated fibroblasts determines the histological signature of lung adenocarcinoma. Cancer Res. (2021)
Applications
IF, Confocal Microscopy
Kato T et al. Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice. J Mol Endocrinol. (2021)
Applications
IHC, ICC, Histology
Yamagishi M et al. Live-Cell Imaging Technique to Visualize DAMPs Release During Regulated Cell Death. Methods Mol Biol. (2021)
Applications
Undefined
Walcheck MT et al. Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice. PLoS One (2021)
Applications
IHC, ICC, Histology
Nakamura Y et al. Modulation of both intrinsic and extrinsic factors additively promotes rewiring of corticospinal circuits after spinal cord injury. J Neurosci. (2021)
Applications
Undefined
Comeras LB et al. NPY released from GABA neurons of the dentate gyrus specially reduces contextual fear without affecting cued or trace fear. Front Synaptic Neurosci. (2021)
Applications
IHC, ICC, Histology
Barettino C et al. Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation. Front Cell Dev Biol. (2021)
Applications
IHC, ICC, Histology
Dorsett C. et al. The impact of SST and PV interneurons on nonlinear synaptic integration in the neocortex. eNeuro. (2021)
Applications
IF, Confocal Microscopy
Feng T et al. Experience-dependent inhibitory plasticity is mediated by CCK+ basket cells in the developing dentate gyrus. J Neurosci. (2021)
Applications
IHC, ICC, Histology
Murai S et al. Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution. Methods Mol Biol. (2021)
Applications
Undefined
Tran TM et al. An Optimized Whole‐Mount Immunofluorescence Method for Shoot Apices. Curr Protoc. (2021)
Applications
Undefined
Yu W et al. Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation In Vivo with CalExflox Mice. J Neurosci. (2021)
Applications
IHC, ICC, Histology
Quan W et al. Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1‐transgenic mice. Glia. (2021)
Applications
IHC, ICC, Histology
Parolari L et al. Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson's disease and OCD-like behaviors in mice. Mol Psychiatry. (2021)
Applications
IHC, ICC, Histology
Goossens MG et al. Level of hM4D (Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus. eNeuro. (2021)
Applications
IHC, ICC, Histology
Gilissen SRJ et al. Reconsidering the border between the visual and posterior parietal cortex of mice. Cereb Cortex. (2021)
Applications
IHC, ICC, Histology
Krammer DJ et al. Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell Rep. (2021)
Applications
IHC, ICC, Histology
Semerci F et al. Mouse models for studying hippocampal adult neural stem cell biology. Methods Mol Biol. (2021)
Applications
Undefined
Tang W et al. Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol. (2021)
Applications
IF, Confocal Microscopy
Lumaquin D et al. An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish. Elife. (2021)
Applications
IHC, ICC, Histology
Vetere G et al. An inhibitory hippocampal-thalamic pathway modulates remote memory retrieval. Nat Neurosci. (2021)
Applications
IHC, ICC, Histology
Xiao L et al. Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird. Nat Commun. (2021)
Applications
IHC, ICC, Histology; WB, IB, PCA
Ibrayeva A et al. Early stem cell aging in the mature brain. Cell Stem Cell. (2021)
Applications
IHC, ICC, Histology
Ortin-Martinez A et al. Photoreceptor nanotubes mediate the in vivo exchange of intracellular material. EMBO J. (2021)
Applications
IF, Confocal Microscopy
Quina LA. et al. GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum. eNeuro (2020)
Applications
IF, Confocal Microscopy
Fu DJ. et al. Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun. (2020)
Applications
IF, Confocal Microscopy
Bell OH. et al. Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol. (2020)
Applications
IHC, ICC, Histology
Burrus CJ. et al. Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep. (2020)
Applications
IHC, ICC, Histology
Wykes AD. et al. Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter. IBRO Rep. (2020)
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
Yuan T. et al. Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol. (2020)
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
Zapiec B. et al. The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Nam HS, Capecchi MR. Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. Neural Dev. (2020)
Applications
IF, Confocal Microscopy
Lee S et al. Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea. Sci Rep. (2020)
Applications
IF, Confocal Microscopy
Eun K. et al. Transcriptional activities of human elongation factor-1α and cytomegalovirus promoter in transgenic dogs generated by somatic cell nuclear transfer. PLoS One. (2020)
Applications
IHC, ICC, Histology
Amano K. et al. Indian hedgehog in craniofacial neural crest cells links to skeletal malocclusion by regulating associated cartilage formation and gene expression. FASEB J. (2020)
Applications
Undefined
Ide S, Yahara Y, Kobayashi Y, et al. Yolk-sac-derived macrophages progressively expand in the mouse kidney with age. Elife (2020)
Applications
IF, Confocal Microscopy
Bruzsik B. et el. Somatostatin neurons of the bed nucleus of stria terminalis enhance associative fear memory consolidation in mice. J Neurosci. (2020)
Applications
IHC, ICC, Histology
Marubashi S, Fukuda M. Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes. Cell Struct Funct. (2020)
Applications
WB, IB, PCA
Skelton PD, Poquerusse J, Salinaro JR, Li M, Luikart BW. Activity-dependent dendritic elaboration requires Pten. Neurobiol Dis. (2020)
Applications
IHC, ICC, Histology
Nasirova N, Quina LA, Agosto-Marlin IM, Ramirez JM, Lambe EK, Turner EE. Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons. J Comp Neurol. (2020)
Applications
Undefined
Tomorsky J. et al. Effects of nectin-3 misexpression on dendritic spine density during the postnatal development of layer 2/3 cortical neurons. Neural Dev (2020)
Applications
IHC, ICC, Histology
Cao Y, Lipka J, Stucchi R, et al. Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol. (2020)
Applications
IF, Confocal Microscopy
Patoori S, Jean-Charles N, Gopal A, et al. Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. Neural Dev. (2020)
Applications
Undefined
Fumagalli A, Oost KC, Kester L, et al. Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell (2020)
Applications
IF, Confocal Microscopy
Gao Y, Yan Y, Tripathi S, et al. LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology (2020)
Applications
Undefined
Wang Z, Zheng Y, Zheng M, et al. Neurogenic Niche Conversion Strategy Induces Migration and Functional Neuronal Differentiation of Neural Precursor Cells Following Brain Injury. Stem Cells Dev. (2020)
Applications
IF, Confocal Microscopy
Deng J, Ni Z, Gu W, et al. Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors. Cell Mol Life Sci. (2020)
Applications
IF, Confocal Microscopy
Ishimoto H, Kamikouchi A. A Feedforward Circuit Regulates Action Selection of Pre-mating Courtship Behavior in Female Drosophila. Curr Biol. (2020)
Applications
Undefined
Stephenson-Jones M, Bravo-Rivera C, Ahrens S, et al. Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors. Neuron (2020)
Applications
Undefined
Parmhans N. Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. J Comp Neurol. (2020)
Applications
IF, Confocal Microscopy; WB, IB, PCA
Cymerblit-Sabba A, Smith AS, Williams Avram SK, et al. Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Front Mol Neurosci. (2020)
Applications
IHC, ICC, Histology
Hu Y, Li J, Zhu Y, et al. Development and characterization of an Otp conditional loss of function allele. Genesis (2020)
Applications
IF, Confocal Microscopy
Vila Ellis L, Cain MP, Hutchison V, et al. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. (2020)
Applications
IF, Confocal Microscopy
Ozguldez HO, Fan R, Bedzhov I. Placental gene editing via trophectoderm-specific Tat-Cre/loxP recombination. Development (2020)
Applications
Undefined
Amemori S, Amemori KI, Yoshida T, et al. Microstimulation of primate neocortex targeting striosomes induces negative decision-making. Eur J Neurosci. (2020)
Applications
Undefined
Reed-Geaghan EG, Croxford AL, Becher B, Landreth GE. Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. J Exp Med. (2020)
Applications
IF, Confocal Microscopy
Scekic-Zahirovic J. et al. Genetic ablation of SOD1G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression. bioRxiv (2020)
Applications
IF, Confocal Microscopy
Nagoya T, Kamimura K, Inoue R, et al. Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. Neurogastroenterol Motil. Neurogastroenterol Motil. (2020)
Applications
IF, Confocal Microscopy
Lo, H.C., Xu, Z., Kim, I.S. et al. Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer (2020)
Applications
Undefined
Hennes M, Lombaert N, Wahis J, Van den Haute C, Holt MG, Arckens L. Astrocytes shape the plastic response of adult cortical neurons to vision loss. Glia (2020)
Applications
Undefined
Brignani S, Raj DDA, Schmidt ERE, et al. Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron (2020)
Applications
Undefined
Morral C, Stanisavljevic J, Hernando-Momblona X, et al. Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell. (2020)
Applications
Undefined
Zhang YH. et al. Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus. bioRxiv (2020)
Applications
IHC, ICC, Histology
Sun C, Sakashita H, Kim J, et al. Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis. Cell Stem Cell. (2020)
Applications
Undefined
Sawant D, Klevenow E, Baeten JT, et al. Generation of transgenic mice that conditionally express microRNA miR-145. Genesis. (2020)
Applications
Undefined
Colasante G, Qiu Y, Massimino L, et al. In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Brain (2020)
Applications
IHC, ICC, Histology
Niu X, Subramanian A, Hwang TH, Schilling TF, Galloway JL. Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Curr Biol. (2020)
Applications
IF, Confocal Microscopy
Uchigashima M. et al. A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus. ELife (2020)
Applications
IHC, ICC, Histology
Guan Z, Quiñones-Frías MC, Akbergenova Y, Littleton JT. Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner. Elife (2020)
Applications
WB, IB, PCA
Kim CK, Saxena M, Maharjan K, et al. Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. Cell Mol Gastroenterol Hepatol. (2020)
Applications
IF, Confocal Microscopy
Yokota T, McCourt J, Ma F, et al. Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell. (2020)
Applications
ISH, FISH
Suter TACS, Blagburn SV, Fisher SE, Anderson-Keightly HM, D'Elia KP, Jaworski A. TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. (2020)
Applications
IHC, ICC, Histology
Moehlman AT. et al. Regulation of the Unfolded Protein Response by BiP AMPylation protects photoreceptors from light-dependent degeneration. bioRxiv (2020)
Applications
IHC, ICC, Histology
Liu K, Tang M, Jin H, et al. Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem. (2020)
Applications
IF, Confocal Microscopy
Giovanniello J. et al. A central amygdala-globus pallidus circuit conveys unconditioned stimulus information and controls fear learning. J Neurosci. (2020)
Applications
IHC, ICC, Histology
Tang R. et al. G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv (2020)
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
Tang R. et al. G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv (2020)
Applications
WB, IB, PCA
Sun D, Schur RM, Sears AE, et al. Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. Mol Ther. (2020)
Applications
Undefined
Salamon RJ, Zhang Z, Mahmoud AI. Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. J Vis Exp. (2020)
Applications
IF, Confocal Microscopy
Drake KA, Chaney CP, Das A, et al. Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development. (2020)
Applications
Undefined
Chen C, Willhouse AH, Huang P, et al. Characterization of a Knockin Mouse Line Expressing a Fusion Protein of Kappa Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging Via CLARITY [published online ahead of print, 2020 Jun 19]. eNeuro. 2020;ENEURO.0028-20.2020. doi:10.1523/ENEURO.0028-20.2020 (2020)
Applications
IHC, ICC, Histology
McQueen BE, Kiatthanapaiboon A, Fulcher ML, et al. A Human Fallopian Tube Epithelial Cell Culture Model to Study Host Responses to Chlamydia trachomatis Infection Infect Immun. (2020)
Applications
Undefined
Gaggioli V. et al. Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. PLoS Genet (2020)
Applications
IF, Confocal Microscopy
Guo M, Li Y, Su Y, et al. Rapid image deconvolution and multiview fusion for optical microscopy. Nat Biotechnol. (2020)
Applications
Undefined
Deryckere A, Stappers E, Dries R, et al. Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development. (2020)
Applications
Undefined
Pasquettaz R, Kolotuev I, Rohrbach A, Gouelle C, Pellerin L, Langlet F. Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol. (2020)
Applications
IF, Confocal Microscopy
Vaughan SK. Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging. bioRxiv (2020)
Applications
IP, Co-IP
Nijenhuis W, van Grinsven MMP, Kapitein LC. An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol. (2020)
Applications
IF, Confocal Microscopy
Tang M, Liu K, Jin H, et al. Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter J Mol Cell Cardiol. (2020)
Applications
IF, Confocal Microscopy
Sheahan T. et al. The neurokinin-1 receptor is expressed with gastrin-releasing peptide receptor in spinal interneurons and modulates itch. J Neurosci. (2020)
Applications
IHC, ICC, Histology
Browning JR, Derr P, Derr K, et al. A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue. Oncotarget. (2020)
Applications
IHC, ICC, Histology
Li Y, Lv Z, Zhang S, et al. Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis. Dev Cell. (2020)
Applications
Undefined
Kim SH, Bahia PK, Patil M, et al. Development of a mouse reporter strain for the purinergic P2X2 receptor. eNeuro. (2020)
Applications
IF, Confocal Microscopy
Vale R. A cortico-collicular circuit for accurate orientation to shelter during escape. bioRxiv (2020)
Applications
IHC, ICC, Histology
Wang Z, Wang F, Zhong J, et al. Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun. (2020)
Applications
IF, Confocal Microscopy
Göngrich C, Krapacher FA, Munguba H, et al. ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol. (2020)
Applications
IHC, ICC, Histology
Kim JE, Fei L, Yin WC, et al. Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun. (2020)
Applications
IHC, ICC, Histology
Yang Z, Ma S, Cao R, et al. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. J Invest Dermatol. (2020)
Applications
Undefined
Laiouar S, Berns N, Brech A, Riechmann V. RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism. Curr Biol. (2020)
Applications
Undefined
Probst S. Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Cell Rep (2020)
Applications
IF, Confocal Microscopy
Singla S, Iwamoto-Stohl LK, Zhu M, Zernicka-Goetz M. Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism. Nat Commun. (2020)
Applications
IF, Confocal Microscopy
Vermeer JAF, Ient J, Markelc B, et al. A lineage-tracing tool to map the fate of hypoxic tumour cells. Dis Model Mech. (2020)
Applications
IF, Confocal Microscopy
Tu R, Duan B, Song X, Xie T. Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation. Sci Adv. (2020)
Applications
IF, Confocal Microscopy
Zwiggelaar RT. LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Sci Adv. (2020)
Applications
IF, Confocal Microscopy
Kao CY, Xu M, Wang L, et al. Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. (2020)
Applications
IHC, ICC, Histology
Maheshwari U, Kraus D, Vilain N, et al. Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Cammack AJ, Moudgil A, Chen J, et al. A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues. Proc Natl Acad Sci U S A. (2020)
Applications
Undefined
Angueira AR et al. Defining the lineage of thermogenic perivascular adipose tissue. Nat Metab. (2020)
Applications
IF, Confocal Microscopy
Levy JM, Yeh WH, Pendse N, et al. Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nat Biomed Eng. (2020)
Applications
IF, Confocal Microscopy
Ueno M, Nakamura Y, Nakagawa H, et al. Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury. Cereb Cortex. (2020)
Applications
IHC, ICC, Histology
Seymour PA, Collin CA, Egeskov-Madsen AR, et al. Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Dev Cell. (2020)
Applications
IF, Confocal Microscopy
Dziengelewski C, Rodrigue MA, Caillier A, et al. Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death. J Cell Biol. (2020)
Applications
Undefined
Luciani A, Schumann A, Berquez M, et al. Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. (2020)
Applications
Undefined
Li B, Nguyen TP, Ma C, Dan Y. Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons Proc Natl Acad Sci U S A. (2020)
Applications
Undefined
Kim SJ, Garcia-Recio S, Creighton CJ, Perou CM, Rosen JM. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene. (2020)
Applications
IF, Confocal Microscopy
Mignocchi N. Development of a genetically-encoded oxytocin sensor. bioRxiv (2020)
Applications
IHC, ICC, Histology
Tan SH, Swathi Y, Tan S, et al. AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature. (2020)
Applications
IHC, ICC, Histology
Zhou T, Gao B, Fan Y, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. Elife. (2020)
Applications
IHC, ICC, Histology; WB, IB, PCA
Tian X, He L, Liu K, et al. Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J. (2020)
Applications
Undefined
Dong Z, Chen W, Chen C, et al. CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation. Neuron. (2020)
Applications
Undefined
Pu W, Han X, He L, et al. A genetic system for tissue-specific inhibition of cell proliferation. Development. (2020)
Applications
Undefined
Sun X, Are A, Annusver K, et al. Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife. (2020)
Applications
ISH, FISH
Wang WX et al.. Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons. Nat Commun. (2020)
Applications
IHC, ICC, Histology
Gantner CW, de Luzy IR, Kauhausen JA, et al. Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell. (2020)
Applications
IHC, ICC, Histology
Lieberman OJ, Frier MD, McGuirt AF, et al. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. Elife. (2020)
Applications
IF, Confocal Microscopy
Grimsley-Myers CM, Isaacson RH, Cadwell CM, et al. VE-cadherin endocytosis controls vascular integrity and patterning during development. J Cell Biol. (2020)
Applications
IF, Confocal Microscopy
Brent A. Adipokines set neural tone by regulating synapse number. Cell Metab. (2020)
Applications
IF, Confocal Microscopy
Wang J. Cocaine Triggers Glial-Mediated Synaptogenesis. Biol Psychiatry. (2020)
Applications
IHC, ICC, Histology
Lo LH, Dong R, Lyu Q, Lai KO. The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Maziarz M, Park JC, Leyme A, et al. Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design. Cell. (2020)
Applications
WB, IB, PCA
Choi EB. ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells. bioRxiv (2020)
Applications
WB, IB, PCA
Roome RB. Phox2a defines a developmental origin of the anterolateral system in mice and humans. Cell Rep (2020)
Applications
IHC, ICC, Histology
Najafi F, Elsayed GF, Cao R, et al. Excitatory and Inhibitory Subnetworks Are Equally Selective during Decision-Making and Emerge Simultaneously during Learning. Neuron. (2020)
Applications
IF, Confocal Microscopy
Kebschull JM. Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set. Science (2020)
Applications
IF, Confocal Microscopy
Comer AL, Jinadasa T, Sriram B, et al. Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction. PLoS Biol. (2020)
Applications
IF, Confocal Microscopy
Carriere CH. The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death. J Neurosci (2020)
Applications
IF, Confocal Microscopy
Muller PA, Schneeberger M, Matheis F, et al. Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature. (2020)
Applications
IF, Confocal Microscopy
Minkowicz MW. Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis. bioRxiv (2020)
Applications
IHC, ICC, Histology
Lau AN, Li Z, Danai LV, et al. Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. (2020)
Applications
IF, Confocal Microscopy
Lee EJ et al. A psychological stressor conveyed by appetite-linked neurons. Sci Adv. (2020)
Applications
IF, Confocal Microscopy
Bruens L et al. Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Aboualizadeh E et al. Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution. Stem Cell Reports (2020)
Applications
IHC, ICC, Histology
Marjanovic ND et al. Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell. (2020)
Applications
Undefined
LaFave LM et al. Epigenomic state transitions characterize tumor progression in mouse lung adenocarcinoma. Cancer Cell. (2020)
Applications
Undefined
Kaur N et al. Neural stem cells direct axon guidance via their radial fiber scaffold. Neuron. (2020)
Applications
Undefined
Phoon YP et al. Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes. Exp Cell Res. (2020)
Applications
IF, Confocal Microscopy
Sheng X et al. Cycling stem cells are radioresistant and regenerate the intestine. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Kennedy T et al. Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model. BMC Biol. (2020)
Applications
IF, Confocal Microscopy
Ricci B et al. Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. Elife (2020)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Zhou H et al. IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol. (2020)
Applications
IF, Confocal Microscopy
Zhou X et al. Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun. (2020)
Applications
IF, Confocal Microscopy
Henschke JU et al. Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas. Elife (2020)
Applications
IHC, ICC, Histology
Liu X et al. Cell-type-specific gene inactivation and in situ restoration via recombinase-based flipping of targeted genomic region. J Neurosci. (2020)
Applications
IF, Confocal Microscopy
Hamada N et al. Neuropathophysiological significance of the c. 1449T> C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome. Biochem Biophys Res Commun. (2020)
Applications
Undefined
Su J et al. Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. J Neurosci. (2020)
Applications
Undefined
Robb KP et al. Adipose stromal cells enhance decellularized adipose tissue remodeling through multimodal mechanisms. Tissue Eng Part A (2020)
Applications
IHC, ICC, Histology
Terra H et al. Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition. Curr Biol. (2020)
Applications
IHC, ICC, Histology
Eadaim A et al. Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-Kv4/Shal Coupled Regulatory System. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Nicolas-Avila JA et al. A network of macrophages supports mitochondrial homeostasis in the heart. Cell. (2020)
Applications
Undefined
Xiao X et al. A genetically defined compartmentalized striatal direct pathway for negative reinforcement. Cell. (2020)
Applications
Undefined
Ribeiro M et al. Neural Cadherin Plays Distinct Roles for Neuronal Survival and Axon Growth under Different Regenerative Conditions. eNeuro. (2020)
Applications
IHC, ICC, Histology
Li YR et al. Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants. Genome Res. (2020)
Applications
Undefined
Negwer M et al. EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Struct Funct. (2020)
Applications
IF, Confocal Microscopy
Paris AJ et al. STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. (2020)
Applications
IHC, ICC, Histology
Usseglio G et al. Control of orienting movements and locomotion by Projection-Defined subsets of brainstem V2a neurons. Curr Biol. (2020)
Applications
IHC, ICC, Histology
Zhang JQ et al. The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor. Oncogene. (2020)
Applications
Undefined
Tang R et al. A versatile system to record cell-cell interactions. Elife (2020)
Applications
WB, IB, PCA
Cassandras M et al. Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. (2020)
Applications
IF, Confocal Microscopy
Morello F et al. Molecular fingerprint and developmental regulation of the tegmental GABAergic and glutamatergic neurons derived from the anterior hindbrain. Cell Rep. (2020)
Applications
IHC, ICC, Histology
Nasirova N et al. Mapping Cell Types and Efferent Pathways in the Ascending Relaxin-3 System of the Nucleus Incertus. eNeuro. (2020)
Applications
IF, Confocal Microscopy
Gilich A et al. Capillary cell-type specialization in the alveolus. Nature. (2020)
Applications
IF, Confocal Microscopy
Adrados CS et al. Salamander‐Eci: An optical clearing protocol for the three‐dimensional exploration of regeneration. Dev Dyn. (2020)
Applications
IF, Confocal Microscopy
Sural S et al. HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sci Adv. (2020)
Applications
WB, IB, PCA
Garcia-Prat L et al. FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. Nat Cell Biol. (2020)
Applications
Undefined
Maziarz M et al. Naturally occurring hotspot cancer mutations in Gα13 promote oncogenic signaling. J Biol Chem. (2020)
Applications
WB, IB, PCA
Fu W et al. An Aurora Kinase B–Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. Front Cell Dev Biol (2020)
Applications
IF, Confocal Microscopy
Chon U et al. Topographically Distinct Projection Patterns of Early-Generated and Late-Generated Projection Neurons in the Mouse Olfactory Bulb. eNeuro. (2020)
Applications
IHC, ICC, Histology
Matsuda T et al. Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake. Nat Commun. (2020)
Applications
IHC, ICC, Histology
Morenilla-Palao C et al. A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. Sci Adv. (2020)
Applications
IHC, ICC, Histology
Ma H et al. Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction. Cell Rep Med. (2020)
Applications
IF, Confocal Microscopy
O'Shea TM et al. Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions. Nat Commun. (2020)
Applications
IHC, ICC, Histology
Wang J et al. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep. (2020)
Applications
IHC, ICC, Histology
Moiseenko A et al. Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep. (2020)
Applications
IF, Confocal Microscopy
Leung C et al. Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation. Cell Rep. (2020)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Alizzi RA et al. The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PLoS Genet. (2020)
Applications
IF, Confocal Microscopy
Uchida S et al. A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice. J Neurosci. (2020)
Applications
IHC, ICC, Histology
Turchetto S et al. Ex Vivo Recording of Axonal Transport Dynamics on Postnatal Organotypic Cortical Slices. STAR Protoc. (2020)
Applications
IF, Confocal Microscopy
Roscoe S et al. Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol. (2020)
Applications
WB, IB, PCA
Roscoe S et al. Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol. (2020)
Applications
Undefined
Chen Q et al. Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation. STAR Protoc. (2020)
Applications
IF, Confocal Microscopy
Maenohara Y et al. Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells. J Bone Miner Res. (2020)
Applications
Undefined
Kuo CC, Hsieh JC, Tsai HC, et al. Inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. J Physiol (2020)
Applications
Undefined
Chen Q, Rehman J, Chan M, et al. Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep. (2020)
Applications
Undefined
Myers KR. et al. The nebulin family LIM and SH3 proteins regulate postsynaptic development and function. J Neurosci. (2020)
Applications
Undefined
Basrur, NS et al. Fruitless mutant male mosquitoes gain attraction to human odor. ELife (2020)
Applications
IF, Confocal Microscopy
Ingvarsen, SZ et al. Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis. Scientific Reports (2020)
Applications
IHC, ICC, Histology
Kwon, JB et al. In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development (2020)
Applications
IF, Confocal Microscopy
Diaz, JL et al. An evolutionarily acquired microRNA shapes development of mammalian cortical projections. Proceedings of the National Academy of Sciences of the United States of America (2020)
Applications
IHC, ICC, Histology
Duhart, JM et al. Modulation of sleep-courtship balance by nutritional status in Drosophila. ELife (2020)
Applications
IHC, ICC, Histology
Li, TM et al. Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation. Scientific Reports (2020)
Applications
IF, Confocal Microscopy
Green, SM et al. Retrograde Labeling Illuminates Distinct Topographical Organization of D1 and D2 Receptor-Positive Pyramidal Neurons in the Prefrontal Cortex of Mice. ENeuro (2020)
Applications
IHC, ICC, Histology
Krienen, FM et al. Innovations present in the primate interneuron repertoire. Nature (2020)
Applications
IHC, ICC, Histology
Klouda, T et al. From 2D to 3D: Promising Advances in Imaging Lung Structure. Frontiers in Medicine (2020)
Applications
IF, Confocal Microscopy
Kim, H et al. The DMCdrive: practical 3D-printable micro-drive system for reliable chronic multi-tetrode recording and optogenetic application in freely behaving rodents. Scientific Reports (2020)
Applications
IHC, ICC, Histology
Harris, JM et al. Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Developmental Cell (2020)
Applications
IHC, ICC, Histology
Pflügler, S et al. IDO1+ Paneth cells promote immune escape of colorectal cancer. Communications Biology (2020)
Applications
IHC, ICC, Histology
Gong, X et al. An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques. Neuron (2020)
Applications
IHC, ICC, Histology
Lennox, AL et al. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron (2020)
Applications
IF, Confocal Microscopy
Luciani, A et al. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications (2020)
Applications
IF, Confocal Microscopy
Su, J et al. TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Nature (2020)
Applications
IF, Confocal Microscopy
Novak, S et al. Osteoclasts Derive Predominantly from Bone Marrow-Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair. Journal of Immunology (Baltimore, Md. : 1950) (2020)
Applications
IF, Confocal Microscopy
Reynolds et al. Multiplexed calcium imaging of single-synapse activity and astroglial responses in the intact brain. Neuroscience Letters (2019)
Applications
IF, Confocal Microscopy
Zhou et al. Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition. Protein & Cell (2019)
Applications
IF, Confocal Microscopy
Tang et al. E-cadherin is Required for the Homeostasis of Lgr5+ Gastric Antral Stem Cells. International Journal of Biological Sciences (2019)
Applications
IHC, ICC, Histology
Spence et al. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nature Communications (2019)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Murakami et al. Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Scientific Reports (2019)
Applications
IF, Confocal Microscopy
Webster et al. Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina. Investigative Ophthalmology & Visual Science (2019)
Applications
IF, Confocal Microscopy
Narbonne-Reveau et al. Developmental regulation of regenerative potential in Drosophila by ecdysone through a bistable loop of ZBTB transcription factors. PLOS Biology (2019)
Applications
IHC, ICC, Histology
Hannafon et al. Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells. Cell Communication and Signaling (2019)
Applications
WB, IB, PCA
Jeon et al. Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model. Cell Death & Differentiation (2019)
Applications
IF, Confocal Microscopy
Magloire et al. KCC2 overexpression prevents the paradoxical seizure-promoting action of somatic inhibition. Nature Communications (2019)
Applications
IHC, ICC, Histology
Zhao C, Sun Q, Tang L, et al. Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance. Front Endocrinol (Lausanne) (2019)
Applications
WB, IB, PCA
Bohlen MO, El-Nahal HG, Sommer MA. Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques. Front Neuroanat. (2019)
Applications
IHC, ICC, Histology
Sessions GA, Copp ME, Liu JY, Sinkler MA, D'Costa S, Diekman BO. Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture. FASEB J. (2019)
Applications
IHC, ICC, Histology
Toch M, Clotman F. CBP and p300 coactivators contribute to the maintenance of Isl1 expression by the Onecut transcription factors in embryonic spinal motor neurons. Mol Cell Neurosci. (2019)
Applications
Undefined
Kim AJ, Alfieri CM, Yutzey KE. Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease. Anat Rec (Hoboken) (2019)
Applications
IHC, ICC, Histology
Lee KS, Vandemark K, Mezey D, Shultz N, Fitzpatrick D. Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex. Neuron (2019)
Applications
IF, Confocal Microscopy
Aggarwal S, Tang C, Sing K, Kim HW, Millar RP, Tello JA. Medial Amygdala Kiss1 Neurons Mediate Female Pheromone Stimulation of Luteinizing Hormone in Male Mice. Neuroendocrinology (2019)
Applications
IHC, ICC, Histology
Foggetti A, Baccini G, Arnold P, Schiffelholz T, Wulff P. Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Taguchi K, Elias BC, Qian S, Brooks CR. Quantifying autophagic flux in kidney tissue using structured illumination microscopy. Methods Cell Biol. (2019)
Applications
Undefined
Khuu MA, Pagan CM, Nallamothu T, et al. Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus. J Neurosci. (2019)
Applications
IHC, ICC, Histology
Dalghi MG, Clayton DR, Ruiz WG, et al. Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol. (2019)
Applications
Undefined
Collins BC, Arpke RW, Larson AA, et al. Estrogen Regulates the Satellite Cell Compartment in Females. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Nguyen UP, Imamura F. Regional differences in mitral cell development in mouse olfactory bulb. J Comp Neurol. (2019)
Applications
Undefined
Sears JC, Choi WJ, Broadie K. Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry. Neurobiol Dis. (2019)
Applications
IHC, ICC, Histology
Li Y, Lv Z, He L, et al. Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res. (2019)
Applications
IF, Confocal Microscopy
Dong X, Xie X, Guo L, et al. Generation and characterization of Lhx4tdT reporter knock-in and Lhx4loxP conditional knockout mice. Genesis (2019)
Applications
IHC, ICC, Histology
Nagai J, Rajbhandari AK, Gangwani MR, et al. Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Cell. (2019)
Applications
IHC, ICC, Histology
Lilley BN, Sabbah S, Hunyara JL, et al. Genetic access to neurons in the accessory optic system reveals a role for Sema6A in midbrain circuitry mediating motion perception. J Comp Neurol. (2019)
Applications
IHC, ICC, Histology
Yamada S, Lav R, Li J, Tucker AS, Green JBA. Molar Bud-to-Cap Transition Is Proliferation Independent. J Dent Res. (2019)
Applications
IF, Confocal Microscopy
Scandola S, Samuel MA. A Flower-Specific Phospholipase D Is a Stigmatic Compatibility Factor Targeted by the Self-Incompatibility Response in Brassica napus. Curr Biol. (2019)
Applications
WB, IB, PCA
Welz PS, Zinna VM, Symeonidi A, et al. BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell (2019)
Applications
IHC, ICC, Histology
Manjila SB, Kuruvilla M, Ferveur JF, Sane SP, Hasan G. Extended Flight Bouts Require Disinhibition from GABAergic Mushroom Body Neurons. Curr Biol. (2019)
Applications
IHC, ICC, Histology
Bertero A, Feyen PLC, Zurita H, Apicella AJ. A Non-Canonical Cortico-Amygdala Inhibitory Loop. J Neurosci. (2019)
Applications
IHC, ICC, Histology
Johnson BL, d'Alincourt Salazar M, Mackenzie-Dyck S, et al. Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice. PLoS One. (2019)
Applications
IF, Confocal Microscopy
Branch A. et al. An optimized protocol for iDISCO+ rat brain clearing, imaging, and analysis. bioRxiv (2019)
Applications
IHC, ICC, Histology
Gunn BG, Sanchez GA, Lynch G, Baram TZ, Chen Y. Hyper-diversity of CRH interneurons in mouse hippocampus. Brain Struct Funct. (2019)
Applications
IF, Confocal Microscopy
Saito Y, Yuan Y, Zucker-Scharff I, et al. Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron (2019)
Applications
IF, Confocal Microscopy
Desloovere J, Boon P, Larsen LE, et al. Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. Epilepsia (2019)
Applications
IF, Confocal Microscopy
Masullo L, Mariotti L, Alexandre N, Freire-Pritchett P, Boulanger J, Tripodi M. Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus. Curr Biol. (2019)
Applications
IHC, ICC, Histology
Hovde K, Gianatti M, Witter MP, Whitlock JR. Architecture and organization of mouse posterior parietal cortex relative to extrastriate areas. Eur J Neurosci. (2019)
Applications
IF, Confocal Microscopy
Bray ER, Yungher BJ, Levay K, et al. Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells. Neuron (2019)
Applications
Undefined
Baimel C, McGarry LM, Carter AG. The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Poulopoulos A, Murphy AJ, Ozkan A, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature (2019)
Applications
IHC, ICC, Histology
Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A. Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. J Comp Neurol. (2019)
Applications
Undefined
Guo J, Otis JM, Suciu SK, et al. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell. (2019)
Applications
Undefined
Takeoka A, Arber S. Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. Cell Rep. (2019)
Applications
IHC, ICC, Histology
Donovan LJ, Spencer WC, Kitt MM, et al. Lmx1b is required at multiple stages to build expansive serotonergic axon architectures. Elife. (2019)
Applications
IHC, ICC, Histology
Hardaway JA, Halladay LR, Mazzone CM, et al. Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward. Neuron. (2019)
Applications
IHC, ICC, Histology
Cheng CW, Biton M, Haber AL, et al. Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell (2019)
Applications
IHC, ICC, Histology
Nakagawa N, Plestant C, Yabuno-Nakagawa K, et al. Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron (2019)
Applications
Undefined
Pérez de Sevilla Müller L, Solomon A, Sheets K, Hapukino H, Rodriguez AR, Brecha NC. Multiple cell types form the VIP amacrine cell population. J Comp Neurol. (2019)
Applications
Undefined
Tränkner D, Boulet A, Peden E, Focht R, Van Deren D, Capecchi M. A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion. Cell Rep. (2019)
Applications
IHC, ICC, Histology
Drake KA, Fessler AR, Carroll TJ. Methods for renal lineage tracing: In vivo and beyond. Methods Cell Biol. (2019)
Applications
Undefined
Jüttner J, Szabo A, Gross-Scherf B, et al. Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans. Nat Neurosci. (2019)
Applications
IF, Confocal Microscopy
Hafner G, Witte M, Guy J, et al. Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs. Cell Rep. (2019)
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Kalebic N, Gilardi C, Stepien B, et al. Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology. Cell Stem Cell. (2019)
Applications
IF, Confocal Microscopy
Henderson NT, Le Marchand SJ, Hruska M, Hippenmeyer S, Luo L, Dalva MB. Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs. Elife. (2019)
Applications
IHC, ICC, Histology
Wu SF, Ja YL, Zhang YJ, Yang CH. Sweet neurons inhibit texture discrimination by signaling TMC-expressing mechanosensitive neurons in Drosophila. Elife. (2019)
Applications
IF, Confocal Microscopy
Yetman MJ, Washburn E, Hyun JH, et al. Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs. Nat Neurosci. (2019)
Applications
IHC, ICC, Histology
Varum S, Baggiolini A, Zurkirchen L, et al. Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. (2019)
Applications
IHC, ICC, Histology
Li R, Zhong C, Yu Y, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. (2019)
Applications
IHC, ICC, Histology
Costa RO, Martins H, Martins LF, et al. Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Cell Rep. (2019)
Applications
WB, IB, PCA
Novais EJ, Diekman BO, Shapiro IM, Risbud MV. p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. Matrix Biol. (2019)
Applications
Undefined
Liu Q, Liu K, Cui G, et al. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet. (2019)
Applications
Undefined
Murai S, Yamaguchi Y, Shirasaki Y, et al. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nat Commun. (2019)
Applications
LCI-S, SMART, FRET
Masselink W, Reumann D, Murawala P, et al. Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. (2019)
Applications
IHC, ICC, Histology
Etoh K, Fukuda M. Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors. J Cell Sci. (2019)
Applications
IP, Co-IP
Xuan F, Yano F, Mori D, et al. Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. Arthritis Res Ther. (2019)
Applications
IHC, ICC, Histology
Er EE, Valiente M, Ganesh K, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. (2019)
Applications
IHC, ICC, Histology
Angelova A, Platel JC, Béclin C, Cremer H, Coré N. Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation. J Comp Neurol. (2019)
Applications
IF, Confocal Microscopy
Han X, Wang Y, Pu W, et al. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration. Stem Cell Reports. (2019)
Applications
IF, Confocal Microscopy
Goldstein JM, Tabebordbar M, Zhu K, et al. In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Maximov V, Chen Z, Wei Y, et al. Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma. Nat Commun. (2019)
Applications
IF, Confocal Microscopy
Rusu P, Shao C, Neuerburg A, et al. GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile. Cell Stem Cell. (2019)
Applications
Undefined
Tang Q, Xu M, Xu J, Xie X, Yang H, Gan L. Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. (2019)
Applications
Undefined
Portugaliza HP, Llorà-Batlle O, Rosanas-Urgell A, Cortés A. Reporter lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum. Sci Rep. (2019)
Applications
IF, Confocal Microscopy
Tai Y, Gallo NB, Wang M, Yu JR, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. (2019)
Applications
IHC, ICC, Histology
Krienen FM. et al. Innovations in Primate Interneuron Repertoire. Nature (2019)
Applications
IHC, ICC, Histology
Redmond SA, Figueres-Oñate M, Obernier K, et al. Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
DeNardo LA, Liu CD, Allen WE, et al. Temporal evolution of cortical ensembles promoting remote memory retrieval. Nat Neurosci. (2019)
Applications
iDISCO
De S, Van Deren D, Peden E, et al. Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development. (2019)
Applications
IHC, ICC, Histology
Hamon A, García-García D, Ail D, et al. Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Genovese S, Clément R, Gaultier C, et al. Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors. Elife. (2019)
Applications
IHC, ICC, Histology
Fossati M, Assendorp N, Gemin O, et al. Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron (2019)
Applications
WB, IB, PCA
Weil MT, Ruhwedel T, Meschkat M, Sadowski B, Möbius W. Transmission Electron Microscopy of Oligodendrocytes and Myelin. Methods Mol Biol. (2019)
Applications
Immuno-EM
Li W, Yang L, He Q, et al. A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling. Cell Stem Cell. (2019)
Applications
IF, Confocal Microscopy
Wang X, Tucciarone J, Jiang S, et al. Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Ren SQ, Li Z, Lin S, Bergami M, Shi SH. Precise Long-Range Microcircuit-to-Microcircuit Communication Connects the Frontal and Sensory Cortices in the Mammalian Brain. Neuron. (2019)
Applications
Undefined
Lv X, Ren SQ, Zhang XJ, et al. TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex. Nat Commun. (2019)
Applications
IHC, ICC, Histology
Stabel R, Stüven B, Hansen JN, Körschen HG, Wachten D, Möglich A. Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases. J Mol Biol. (2019)
Applications
WB, IB, PCA
Ahmed SM, Nishida-Fukuda H, Li Y, McDonald WH, Gradinaru CC, Macara IG. Exocyst dynamics during vesicle tethering and fusion. Nat Commun. (2019)
Applications
WB, IB, PCA
Linaro D, Vermaercke B, Iwata R, et al. Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits. Neuron. (2019)
Applications
Undefined
Wu J, Kung J, Dong J, et al. Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Rep. (2019)
Applications
IHC, ICC, Histology
Sanchez Bosch P, Makhijani K, Herboso L, et al. Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues. Dev Cell. (2019)
Applications
Undefined
Sharir A, Marangoni P, Zilionis R, et al. A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nat Cell Biol. (2019)
Applications
IF, Confocal Microscopy
Ellefsen KL, Holt JR, Chang AC, et al. Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol. (2019)
Applications
IF, Confocal Microscopy
Wang Y, Wu H, Zelenin P, et al. Muscle-selective RUNX3 dependence of sensorimotor circuit development. Development. (2019)
Applications
IF, Confocal Microscopy
Brandt R, Sell T, Lüthen M, et al. Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium. Nat Commun. (2019)
Applications
IHC, ICC, Histology
Luo H, Liu HZ, Zhang WW, et al. Interleukin-17 Regulates Neuron-Glial Communications, Synaptic Transmission, and Neuropathic Pain after Chemotherapy. Cell Rep. (2019)
Applications
IF, Confocal Microscopy
Schneeberger M, Parolari L, Das Banerjee T, et al. Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell. (2019)
Applications
iDISCO; IF, Confocal Microscopy
Muller PA. Microbiota imprint gut–intrinsic neuronal programming and sympathetic activity. Nature (2019)
Applications
IF, Confocal Microscopy
Hoa O, Lafont C, Fontanaud P, et al. Imaging and Manipulating Pituitary Function in the Awake Mouse. Endocrinology. (2019)
Applications
IF, Confocal Microscopy
Jayachandran M, Linley SB, Schlecht M, Mahler SV, Vertes RP, Allen TA. Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events. Cell Rep. (2019)
Applications
IHC, ICC, Histology
Bowen ME, McClendon J, Long HK, et al. The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Dev Cell. (2019)
Applications
IHC, ICC, Histology
Johansson J, Naszai M, Hodder MC, et al. RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. (2019)
Applications
IHC, ICC, Histology
Fung C, Tan S, Nakajima M, et al. High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach. PLoS Biol. (2019)
Applications
IF, Confocal Microscopy
Min J, Vega PN, Engevik AC, et al. Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach. Nat Commun. (2019)
Applications
IHC, ICC, Histology
Sheng X. Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells. bioRxiv (2019)
Applications
IF, Confocal Microscopy
Chaimowicz C, Ruffault PL, Chéret C, et al. Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development. (2019)
Applications
IF, Confocal Microscopy
Chen P. The mechanosensitive Piezo1 orchestrating angiogenesis is essential in bone fracture repair. bioRxiv (2019)
Applications
IF, Confocal Microscopy
Smith LR, Irianto J, Xia Y, Pfeifer CR, Discher DE. Constricted migration modulates stem cell differentiation. Mol Biol Cell. (2019)
Applications
IF, Confocal Microscopy
Pekrun K, De Alencastro G, Luo QJ, et al. Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors. JCI Insight. (2019)
Applications
IF, Confocal Microscopy
Fei JF, Lou WP, Knapp D, et al. Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum). Nat Protoc. (2019)
Applications
IF, Confocal Microscopy
Hivert B, Marien L, Agbam KN, Faivre-Sarrailh C. ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. J Cell Sci. (2019)
Applications
IF, Confocal Microscopy
Radomska KJ, Coulpier F, Gresset A, et al. Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells. Cancer Discov. (2019)
Applications
Immuno-EM
Wang Y, Chiang IL, Ohara TE, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. (2019)
Applications
IF, Confocal Microscopy
Fernandez-Perez A, Sathe AA, Bhakta M, Leggett K, Xing C, Munshi NV. Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming. Cell Rep. (2019)
Applications
Undefined
Escalante A. Presynaptic inhibition of cutaneous afferents prevents chronic itch. Cell Rep. (2019)
Applications
IHC, ICC, Histology
Seishima R, Leung C, Yada S, et al. Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development. Nat Commun. (2019)
Applications
IF, Confocal Microscopy
Abramo K, Valton AL, Venev SV, Ozadam H, Fox AN, Dekker J. A chromosome folding intermediate at the condensin-to-cohesin transition during telophase. Nat Cell Biol. (2019)
Applications
WB, IB, PCA
de Castro Abrantes H, Briquet M, Schmuziger C, et al. The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits. J Neurosci. (2019)
Applications
IHC, ICC, Histology
Sun Q, Lee W, Mohri Y, et al. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nat Commun. (2019)
Applications
IF, Confocal Microscopy
Dumas DB. Anatomical development of the cerebellothalamic tract in embryonic mice. bioRxiv (2019)
Applications
IF, Confocal Microscopy
Bayne M. Repeated hypoglycemia blunts the responsiveness of glucose-inhibited GHRH neurons by remodeling neural inputs and disrupting mitochondrial structure and function. JCI Insight. (2019)
Applications
IHC, ICC, Histology
Mukai J, Cannavò E, Crabtree GW, et al. Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. Neuron. (2019)
Applications
IHC, ICC, Histology
Zhou Y, Zhu H, Liu Z, et al. A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nat Neurosci. (2019)
Applications
IF, Confocal Microscopy
Guo M. Accelerating iterative deconvolution and multiview fusion by orders of magnitude. bioRxiv (2019)
Applications
IHC, ICC, Histology
Mohan AS, Dean KM, Isogai T, et al. Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells. Dev Cell. (2019)
Applications
IHC, ICC, Histology
Payne S, Gunadasa-Rohling M, Neal A, et al. Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart. Nat Commun. (2019)
Applications
IHC, ICC, Histology
Masuzzo A, Manière G, Viallat-Lieutaud A, et al. Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition. Elife. (2019)
Applications
IF, Confocal Microscopy
Danner SM, Zhang H, Shevtsova NA, et al. Spinal V3 Interneurons and Left-Right Coordination in Mammalian Locomotion. Front Cell Neurosci. (2019)
Applications
IHC, ICC, Histology
Byrd KM, Piehl NC, Patel JH, et al. Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Cell Stem Cell. (2019)
Applications
IF, Confocal Microscopy
McGlinn E, Holzman MA, Mansfield JH. Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections. Methods Mol Biol. (2019)
Applications
Undefined
Adler A, Zhao R, Shin ME, Yasuda R, Gan WB. Somatostatin-Expressing Interneurons Enable and Maintain Learning-Dependent Sequential Activation of Pyramidal Neurons. Neuron. (2019)
Applications
IF, Confocal Microscopy
VanderWall KB, Vij R, Ohlemacher SK, et al. Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. (2019)
Applications
IF, Confocal Microscopy
Delevich K. Choice suppression through opponent but not independent function of the striatal indirect pathway. bioRxiv (2019)
Applications
IHC, ICC, Histology
Anastasiades PG, Boada C, Carter AG. Cell-Type-Specific D1 Dopamine Receptor Modulation of Projection Neurons and Interneurons in the Prefrontal Cortex. Cereb Cortex. (2019)
Applications
IF, Confocal Microscopy
Ouadah Y, Rojas ER, Riordan DP, Capostagno S, Kuo CS, Krasnow MA. Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. Cell. (2019)
Applications
IF, Confocal Microscopy
Qiu F. microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction. Cerebral Cortex (2019)
Applications
IHC, ICC, Histology
Andres-Alonso M, Ammar MR, Butnaru I, et al. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nat Commun. (2019)
Applications
Undefined
Nowotschin S, Setty M, Kuo YY, et al. The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. (2019)
Applications
IF, Confocal Microscopy
Hanlon, KS et al. Selection of an Efficient AAV Vector for Robust CNS Transgene Expression. Molecular Therapy. Methods & Clinical Development (2019)
Applications
IHC, ICC, Histology
Schaub, C et al. Yorkie and JNK revert syncytial muscles into myoblasts during Org-1-dependent lineage reprogramming. The Journal of Cell Biology (2019)
Applications
IF, Confocal Microscopy
Stine, RR et al. PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell (2019)
Applications
IF, Confocal Microscopy
Kim, S J et al. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene (2019)
Applications
IF, Confocal Microscopy
Green, JE et al. Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization. Current Biology : Cb (2019)
Applications
IHC, ICC, Histology
Modic, M et al. Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell (2019)
Applications
IF, Confocal Microscopy
Bang, JW et al. Sensory noise increases metacognitive efficiency. Journal of Experimental Psychology. General (2019)
Applications
Undefined
Hackett, AR et al. Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. Experimental Neurology (2019)
Applications
IHC, ICC, Histology
Ojala et al. In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ. Molecular Therapy (2018)
Applications
IHC, ICC, Histology
Drummond et al. Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors. Cancer Cell (2018)
Applications
FC, FACS, FLOW; IF, Confocal Microscopy; IHC, ICC, Histology; qRT-PCR, RT-PCR
Chiu et al. Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition. Neuron (2018)
Applications
IF, Confocal Microscopy
Mitew et al. Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner. Nature Communications (2018)
Applications
IHC, ICC, Histology
Dillard et al. Two distinct mechanisms silence chinmo in Drosophila neuroblasts and neuroepithelial cells to limit their self-renewal. Development (2018)
Applications
IHC, ICC, Histology
Asokan et al. A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies. Investigative Ophthalmology & Visual Science (2018)
Applications
IHC, ICC, Histology
Li et al. Genetic targeting of Purkinje fibres by Sema3a-CreERT2. Scientific Reports (2018)
Applications
IF, Confocal Microscopy
Ing-Esteves et al. Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. The Journal of Neuroscience (2018)
Applications
WB, IB, PCA
Crowther et al. An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus. Stem Cell Reports (2018)
Applications
IHC, ICC, Histology
Nichol et al. Electrophysiological and Morphological Characterization of Chrna2 Cells in the Subiculum and CA1 of the Hippocampus: An Optogenetic Investigation. Frontiers in Cellular Neuroscience (2018)
Applications
IHC, ICC, Histology
Miotto et al. Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. Nucleic Acids Research (2018)
Applications
IP, Co-IP; WB, IB, PCA
Yayon et al. Intensify3D: Normalizing signal intensity in large heterogenic image stacks. Scientific Reports (2018)
Applications
iDISCO
Je et al. The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors. Elife (2018)
Applications
IP, Co-IP
Huels et al. Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells. Nature Communications (2018)
Applications
IHC, ICC, Histology; ISH, FISH
Hruska et al. Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nature Neuroscience (2018)
Applications
IF, Confocal Microscopy
Dhandapani et al. Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nature Communications (2018)
Applications
IF, Confocal Microscopy
Ueno et al. Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. Cell Reports (2018)
Applications
IHC, ICC, Histology
Diekman et al. Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging Cell (2018)
Applications
IHC, ICC, Histology
Chung et al. Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development (2018)
Applications
IHC, ICC, Histology
Stuhlmann et al. LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. Nature Communications (2018)
Applications
WB, IB, PCA
Ting et al. A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits. Scientific Reports (2018)
Applications
IHC, ICC, Histology
Suzuki et al. Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. Cell (2018)
Applications
IF, Confocal Microscopy
Rowland et al. Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. Aging (2018)
Applications
IF, Confocal Microscopy
Ye et al. Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. Cellular and Molecular Gastroenterology and Hepatology (2018)
Applications
IHC, ICC, Histology
Roselló-Díez et al. Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice. PLOS Biology (2018)
Applications
IHC, ICC, Histology; TUNEL
Moehlman et al. Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration. Elife (2018)
Applications
IHC, ICC, Histology
Maskari et al. Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics (2018)
Applications
WB, IB, PCA
Johnson et al. Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC. Fluids and Barriers of the CNS (2018)
Applications
IF, Confocal Microscopy
D'Agostino et al. Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake. Cell Metabolism (2018)
Applications
IHC, ICC, Histology; ISH, FISH
Jo et al. Intersectional Strategies for Targeting Amacrine and Ganglion Cell Types in the Mouse Retina. Frontiers in Neural Circuits (2018)
Applications
IHC, ICC, Histology
Chiou et al. Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. Scientific Reports (2018)
Applications
IHC, ICC, Histology
Dolan et al. Communication from Learned to Innate Olfactory Processing Centers Is Required for Memory Retrieval in Drosophila. Neuron (2018)
Applications
IF, Confocal Microscopy
Cerrato et al. Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyte heterogeneity. PLOS Biology (2018)
Applications
IHC, ICC, Histology
Lu et al. miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells (2018)
Applications
IF, Confocal Microscopy
Smith et al. Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations. Communications Biology (2018)
Applications
IHC, ICC, Histology
Rossidis et al. In utero CRISPR-mediated therapeutic editing of metabolic genes. Nature Medicine (2018)
Applications
IF, Confocal Microscopy
Wang et al. Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication. Cell Reports (2018)
Applications
IF, Confocal Microscopy
Jaeger et al. A complex peripheral code for salt taste in Drosophila. Elife (2018)
Applications
IHC, ICC, Histology
Janssen et al. Probing aggrephagy using chemically-induced protein aggregates. Nature Communications (2018)
Applications
IP, Co-IP
Murai et al. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nature Communications (2018)
Applications
LCI-S, SMART, FRET
Murtha et al. Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses. Journal of Clinical Investigation (2018)
Applications
IF, Confocal Microscopy
Ahmed et al. Exocyst dynamics during vesicle tethering and fusion. Nature Communications (2018)
Applications
WB, IB, PCA
Kretzschmar et al. Profiling proliferative cells and their progeny in damaged murine hearts. Proc. Natl. Acad. Sci. U.S.A (2018)
Applications
IF, Confocal Microscopy
Panayotis et al. Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1. Cell Reports (2018)
Applications
IF, Confocal Microscopy
Festa et al. OCRL Deficiency Impairs Endolysosomal Function in a Humanized Mouse Model for Lowe Syndrome and Dent Disease. Human Molecular Genetics (2018)
Applications
IF, Confocal Microscopy
Ollila et al. Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. Journal of Clinical Investigation (2018)
Applications
IHC, ICC, Histology
Lin et al. The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion. Molecular Biology of the Cell (2018)
Applications
WB, IB, PCA
O'Neill et al. Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex. Frontiers in Cellular Neuroscience (2018)
Applications
IF, Confocal Microscopy
Cao et al. Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues. Molecular Metabolism (2018)
Applications
IF, Confocal Microscopy
Onori et al. The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human Mutation (2018)
Applications
WB, IB, PCA
de Melo Guimarães et al. Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2. Frontiers in Cellular Neuroscience (2018)
Applications
IHC, ICC, Histology
Han SY, Clarkson J, Piet R, Herbison AE. et al. Optical Approaches for Interrogating Neural Circuits Controlling Hormone Secretion. Endocrinology (2018)
Applications
IHC, ICC, Histology
Nicholson DA, Roberts TF, Sober SJ. et al. Thalamostriatal and cerebellothalamic pathways in a songbird, the Bengalese finch. J Comp Neurol. (2018)
Applications
IF, Confocal Microscopy
Chen Q, Yang M, Wu H, et al. Genetic lineage tracing analysis of c-kit+ stem/progenitor cells revealed a contribution to vascular injury-induced neointimal lesions. J Mol Cell Cardiol. (2018)
Applications
Undefined
Weng PL, Aure MH, Maruyama T, Ovitt CE. et al. Limited Regeneration of Adult Salivary Glands after Severe Injury Involves Cellular Plasticity. Cell Rep. (2018)
Applications
IHC, ICC, Histology
Kurotsu S, Osakabe R, Isomi M, et al. Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction. Biochem Biophys Res Commun. (2018)
Applications
Undefined
Decker Y, Müller A, Németh E, et al. Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains. Brain Struct Funct. (2018)
Applications
Undefined
Sugimoto S, Ohta Y, Fujii M, et al. Reconstruction of the Human Colon Epithelium In Vivo. Cell Stem Cell (2018)
Applications
IF, Confocal Microscopy
Bast L, Calzolari F, Strasser MK, et al. Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis. Cell Rep. (2018)
Applications
IF, Confocal Microscopy
Yang A, Herter-Sprie G, Zhang H, et al. Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. (2018)
Applications
WB, IB, PCA; IF, Confocal Microscopy
Liu K, Yu W, Tang M, et al. A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development (2018)
Applications
WB, IB, PCA; IF, Confocal Microscopy
Vascak M, Jin X, Jacobs KM, Povlishock JT. Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cereb Cortex. (2018)
Applications
IHC, ICC, Histology
Herndler-Brandstetter D, Ishigame H, Shinnakasu R, et al. KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity (2018)
Applications
FC, FACS, FLOW
Mihaylova MM, Cheng CW, Cao AQ, et al. Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell. (2018)
Applications
IHC, ICC, Histology
Zhang J, Wang Q, Abdul-Aziz D, Mattiacio J, Edge ASB, White PM. ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea. Eur J Neurosci. (2018)
Applications
IF, Confocal Microscopy
Kirschen GW, Kéry R, Liu H, et al. Genetic dissection of the neuro-glio-vascular machinery in the adult brain. Mol Brain. (2018)
Applications
IHC, ICC, Histology
Pu W, He L, Han X, et al. Genetic Targeting of Organ-Specific Blood Vessels. Circ Res. (2018)
Applications
IF, Confocal Microscopy
Minamisawa G, Kwon SE, Chevée M, Brown SP, O'Connor DH. A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Rep. (2018)
Applications
IHC, ICC, Histology
Neirijnck Y, Calvel P, Kilcoyne KR, et al. Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells. FASEB J. (2018)
Applications
Undefined
El-Hayek S, Yang Q, Abbassi L, FitzHarris G, Clarke HJ. Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication. Curr Biol. (2018)
Applications
IF, Confocal Microscopy
Nie X, Kitaoka S, Tanaka K, et al. The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron (2018)
Applications
IF, Confocal Microscopy
Heiss JE, Yamanaka A, Kilduff TS. Parallel Arousal Pathways in the Lateral Hypothalamus. eNeuro (2018)
Applications
IHC, ICC, Histology
Schätzle P, Esteves da Silva M, Tas RP, et al. Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Curr Biol. (2018)
Applications
IF, Confocal Microscopy
Octeau JC, Chai H, Jiang R, Bonanno SL, Martin KC, Khakh BS. An Optical Neuron-Astrocyte Proximity Assay at Synaptic Distance Scales. Neuron (2018)
Applications
IHC, ICC, Histology
Zséli G, Vida B, Szilvásy-Szabó A, Tóth M, Lechan RM, Fekete C. Neuronal connections of the central amygdalar nucleus with refeeding-activated brain areas in rats. Brain Struct Funct. (2018)
Applications
IF, Confocal Microscopy
Li SJ, Vaughan A, Sturgill JF, Kepecs A. A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons. Neuron (2018)
Applications
IF, Confocal Microscopy
Wu Y, Ma L, Duyck K, et al. A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period. Neuron (2018)
Applications
IF, Confocal Microscopy
Orlandi C, Omori Y, Wang Y, et al. Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors. Cell Rep. (2018)
Applications
WB, IB, PCA
Yu X, Taylor AMW, Nagai J, et al. Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior. Neuron (2018)
Applications
IHC, ICC, Histology
Valdearcos M, Douglass JD, Robblee MM, et al. Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metab. (2018)
Applications
IHC, ICC, Histology
Leroy F, Park J, Asok A, et al. A circuit from hippocampal CA2 to lateral septum disinhibits social aggression. Nature. (2018)
Applications
IHC, ICC, Histology
Evans DA, Stempel AV, Vale R, Ruehle S, Lefler Y, Branco T. A synaptic threshold mechanism for computing escape decisions. Nature (2018)
Applications
IHC, ICC, Histology
He L, Li Y, Huang X, et al. Genetic lineage tracing of resident stem cells by DeaLT. Nat Protoc. (2018)
Applications
Undefined
Raz Y, Cohen N, Shani O, et al. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. (2018)
Applications
IF, Confocal Microscopy
Ribeiro IMA, Drews M, Bahl A, Machacek C, Borst A, Dickson BJ. Visual Projection Neurons Mediating Directed Courtship in Drosophila. Cell. (2018)
Applications
IF, Confocal Microscopy
Zhang K, Daigle JG, Cunningham KM, et al. Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell. (2018)
Applications
WB, IB, PCA; IF, Confocal Microscopy
Di Giaimo R, Durovic T, Barquin P, et al. The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis. Cell Rep. (2018)
Applications
IF, Confocal Microscopy
Joost S, Jacob T, Sun X, et al. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing. Cell Rep. (2018)
Applications
IF, Confocal Microscopy
Kurdzo EL, Chuong HH, Evatt JM, Dawson DS. A ZIP1 separation-of-function allele reveals that centromere pairing drives meiotic segregation of achiasmate chromosomes in budding yeast. PLoS Genet. (2018)
Applications
IF, Confocal Microscopy