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Datasheet SDS

RFP Antibody Pre-adsorbed

Rabbit Polyclonal

1187 References
600-401-379S 600-401-379
25 µL 100 µg
Liquid (sterile filtered) Liquid (sterile filtered)
WB, ELISA, IHC, IF, FC, EM, FISH, IP, Multiplex, Other
RFP, mScarlet, rRFP, tdTomato
Rabbit
$125.00 /Per Item
$299.00 /Per Item
25 µL $125.00
100 µg $299.00
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Ships next business day
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Product Details

Anti-RFP (RABBIT) Antibody (Min X Hu Ms & Rt Serum Proteins) - 600-401-379
rabbit anti-RFP antibody, DsRed, rDsRed, Discosoma sp. Red Fluorescent Protein, Red fluorescent protein drFP583.
Rabbit
Polyclonal
IgG

Target Details

DsRed  - View All DsRed Products
RFP, mScarlet, rRFP, tdTomato
Recombinant Protein
The immunogen is a Red Fluorescent Protein (RFP) fusion protein corresponding to the full-length amino acid sequence (234aa) derived from the mushroom anemone Discosoma.
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Red Fluorescent Protein (Discosoma) coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Expect reactivity against RFP and its variants: mCherry, tdTomato, mBanana, mOrange, mPlum, mOrange and mStrawberry. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum and purified and partially purified Red Fluorescent Protein (Discosoma).  No reaction was observed against Human, Mouse or Rat serum proteins.
Q9U6Y8 - UniProtKB

Application Details

ELISA, IF, IHC, WB
EM, FC, FISH, IP, Other, Multiplex  - View References
RFP Antibody Pre-adsorbed is designed for detecting RFP and its variants, tested across ELISA, Western blot, IF, IHC, and suitable for EM, FC, FISH, IP, and multiplex assays. It is applicable for ELISA in both sandwich and capture formats. Researchers should determine optimal titers for specific applications. Recommended starting dilutions are: ELISA 1:28,700 - 1:48,700; FC, IF, IHC 1:200 - 1:2,000; WB 1:1,000 - 1:5,000.

Formulation

1.16 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
RFP Antibody Pre-adsorbed from Rockland Immunochemicals is a high-quality, rabbit polyclonal antibody specifically designed for the detection of red fluorescent protein (RFP) and its variants like mCherry, mScarlet, and tdTomato. This product is suitable for a broad range of applications including Western blot (WB), ELISA, immunohistochemistry (IHC), immunofluorescence (IF), flow cytometry (FC), and more. It is uniquely pre-adsorbed to minimize cross-reactivity, offering high specificity and sensitivity. With over 900 references, this product stands as a proven tool in the scientific community, supporting a wide range of research studies from cellular signaling to disease pathology.
(). Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model. Int J Mol Sci.
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IHC, ICC, Histology
(). Identification of AgRP cells in the murine hindbrain that drive feeding. Mol Metab.
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IHC, ICC, Histology
(). Sox9 regulates alternative splicing and pancreatic beta cell function. Nat Commun.
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IHC, ICC, Histology
(). The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. Nature.
Applications
IF, Confocal Microscopy
(). Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle. Neuron.
Applications
IF, Confocal Microscopy
(). The role of the GABAergic cells of the median raphe region in reinforcement-based learning. Sci Rep.
Applications
IHC, ICC, Histology
(). Deficiency in astrocyte CCL2 production reduces neuroimmune control of Toxoplasma gondii infection. PLoS Pathog.
Applications
FC, FACS, FLOW; IHC, ICC, Histology
(). DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication. Cell Metab.
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IHC, ICC, Histology
(). Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension. Nat Commun.
Applications
IF, Confocal Microscopy
(). Circulating myeloid-derived MMP8 in stress susceptibility and depression. Nature.
Applications
iDISCO; IF, Confocal Microscopy; IHC, ICC, Histology
(). Characterizing enteric neurons in dopamine transporter (DAT)-Cre reporter mice reveals dopaminergic subtypes with dual-transmitter content. Eur J Neurosci.
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IF, Confocal Microscopy
(). Basal delamination during mouse gastrulation primes pluripotent cells for differentiation. Dev Cell.
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IF, Confocal Microscopy
(). Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. Dev Cell.
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IF, Confocal Microscopy
(). Whole-brain connections of glutamatergic neurons in the mouse lateral habenula in both sexes. Biol Sex Differ.
Applications
IF, Confocal Microscopy
(). Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized human neural progenitor cells. iScience.
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WB, IB, PCA
(). Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviors. Nat Neurosci.
Applications
IF, Confocal Microscopy
(). Generation of Slco1a4-CreERT2-tdTomato Knock-in Mice for Specific Cerebrovascular Endothelial Cell Targeting. Int J Mol Sci.
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IF, Confocal Microscopy
(). Overexpression of α-Klotho isoforms promotes distinct Effects on BDNF-Induced Alterations in Dendritic Morphology. Mol Neurobiol.
Applications
IF, Confocal Microscopy
(). Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise. J Physiol.
Applications
IHC, ICC, Histology
(). BRAFV600E mutation and DSS treatment synergize to induce cecal tumor formation in mice. Biochem Biophys Rep.
Applications
IHC, ICC, Histology
(). Two parabrachial Cck neurons involved in the feedback control of thirst or salt appetite. Cell Rep.
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IHC, ICC, Histology
(). Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice. Nat Commun.
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iDISCO
(). Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples. Nat Commun.
Applications
IF, Confocal Microscopy
(). Design and validation of a reporter mouse to study the dynamic regulation of TFEB and TFE3 activity through in vivo imaging techniques. Autophagy.
Applications
IHC, ICC, Histology
(). Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection. Cell Rep.
Applications
IF, Confocal Microscopy
(). Fibroblasts facilitate lymphatic vessel formation in transplanted heart. Theranostics.
Applications
IF, Confocal Microscopy
(). The β-catenin C terminus links Wnt and sphingosine-1-phosphate signaling pathways to promote vascular remodeling and atherosclerosis. Sci Adv.
Applications
IF, Confocal Microscopy
(). A vagal reflex evoked by airway closure. Nature.
Applications
IHC, ICC, Histology
(). A humanized mouse model for adeno-associated viral gene therapy. Nat Commun.
Applications
IF, Confocal Microscopy
(). The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype. Exp Neurol.
Applications
IHC, ICC, Histology
(). The functional and anatomical characterization of three spinal output pathways of the anterolateral tract. Cell Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Crym-positive striatal astrocytes gate perseverative behaviour. Nature.
Applications
IHC, ICC, Histology
(). Identification of the metaphyseal skeletal stem cell building trabecular bone. Sci Adv.
Applications
IF, Confocal Microscopy; Multiplex Assay
(). Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun.
Applications
IHC, ICC, Histology
(). Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas. Cell Discov.
Applications
IF, Confocal Microscopy
(). Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus. Cell Rep,
Applications
IHC, ICC, Histology
(). Bipotent transitional liver progenitor cells contribute to liver regeneration. Nat Genet
Applications
IF, Confocal Microscopy
(). An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains. Cell Rep.
Applications
IF, Confocal Microscopy
(). Epithelial plasticity enhances regeneration of committed taste receptor cells following nerve injury. Exp Mol Med.
Applications
IHC, ICC, Histology
(). LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma. Cancer Discov.
Applications
IHC, ICC, Histology
(). Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell.
Applications
WB, IB, PCA
(). A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex. Nat Neurosci.
Applications
IF, Confocal Microscopy
(). Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells. Cancer Discov.
Applications
IF, Confocal Microscopy
(). hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Organization of orbitofrontal-auditory pathways in the Mongolian gerbil. J Comp Neurol.
Applications
Light-Sheet Microscopy (LSM)
(). CYFIP2 p.Arg87Cys Causes Neurological Defects and Degradation of CYFIP2. Ann Neurol.
Applications
WB, IB, PCA
(). Frequent loss of metastatic ability in subclones of Apc, Kras, Tgfbr2, and Trp53 mutant intestinal tumor organoids. Cancer Sci.
Applications
IHC, ICC, Histology
(). FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Cell Metab.
Applications
IHC, ICC, Histology
(). Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice. Cell Rep.
Applications
IF, Confocal Microscopy
(). Disinhibition of the orbitofrontal cortex biases decision-making in obesity. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1. Cell Rep.
Applications
IHC, ICC, Histology
(). Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis. J Clin Invest.
Applications
IHC, ICC, Histology
(). High-throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory-deprived cortical cholinergic VIP/CHAT neurons. EMBO J.
Applications
iDISCO
(). Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA. Breast Cancer Res.
Applications
IHC, ICC, Histology
(). Genetic impairment of folate metabolism regulates cortical interneurons and social behavior. Front Neurosci.
Applications
IHC, ICC, Histology
(). Heterozygous Dab1 Null Mutation Disrupts Neocortical and Hippocampal Development. eNeuro.
Applications
IHC, ICC, Histology
(). Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila. Nat Commun.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Developmental neuronal origin regulates neocortical map formation. Cell Rep.
Applications
IHC, ICC, Histology
(). Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell.
Applications
IHC, ICC, Histology
(). Peptidergic and functional delineation of the Edinger-Westphal nucleus. Cell Rep.
Applications
IF, Confocal Microscopy
(). Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection. Nat Commun.
Applications
IF, Confocal Microscopy
(). Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding. Am J Physiol Endocrinol Metab.
Applications
IHC, ICC, Histology
(). Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir. Immunity.
Applications
IHC, ICC, Histology
(). Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory. Front Syst Neurosci.
Applications
IF, Confocal Microscopy
(). Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease. Neuron.
Applications
IHC, ICC, Histology
(). A multiplexed in vivo approach to identify driver genes in small cell lung cancer. Cell Rep.
Applications
IHC, ICC, Histology
(). Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease. Cell.
Applications
IF, Confocal Microscopy
(). Dedifferentiation maintains melanocyte stem cells in a dynamic niche. NAture.
Applications
IF, Confocal Microscopy
(). Tcf21 marks visceral adipose mesenchymal progenitors and functions as a rate-limiting factor during visceral adipose tissue development. Call Rep.
Applications
IF, Confocal Microscopy
(). Maresin 1 repletion improves muscle regeneration after volumetric muscle loss. Elife.
Applications
IHC, ICC, Histology
(). Upregulation of breathing rate during running exercise by central locomotor circuits in mice. Nat Commun.
Applications
IHC, ICC, Histology
(). Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis. Nat Immunol.
Applications
IF, Confocal Microscopy
(). Ensheathing glia promote increased lifespan and healthy brain aging. Aging Cell.
Applications
IF, Confocal Microscopy
(). Lrig1 expression identifies quiescent stem cells in the ventricular-subventricular zone from postnatal development to adulthood and limits their persistent hyperproliferation. Neural Dev.
Applications
IF, Confocal Microscopy
(). Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer's disease. Nat Commun.
Applications
IHC, ICC, Histology
(). Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors. Front Bioeng Biotechnol.
Applications
IHC, ICC, Histology
(). A cortico-collicular circuit for orienting to shelter during escape. Nature.
Applications
IHC, ICC, Histology
(). Cue- versus reward-encoding basolateral amygdala projections to nucleus accumbens. Elife.
Applications
IHC, ICC, Histology
(). Notch1 signaling is limited in healthy mature kidneys in vivo. BMC Res Notes.
Applications
IHC, ICC, Histology
(). A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo. Commun Biol.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages. J Exp Med.
Applications
IF, Confocal Microscopy
(). Nigrostriatal dopamine modulates the striatal-amygdala pathway in auditory fear conditioning. Nat Commun.
Applications
IHC, ICC, Histology
(). Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell.
Applications
IF, Confocal Microscopy
(). Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Dev Cell.
Applications
IHC, ICC, Histology
(). Direct Comparison of Epifluorescence and Immunostaining for Assessing Viral Mediated Gene Expression in the Primate Brain. Hum Gene Ther.
Applications
IF, Confocal Microscopy
(). Panoramic visual statistics shape retina-wide organization of receptive fields. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma. Proc Natl Acad Sci U S A.
Applications
IHC, ICC, Histology
(). Generation of Atp6v1g3-Cre mice for investigation of intercalated cells and the collecting duct. Am J Physiol Renal Physiol.
Applications
IF, Confocal Microscopy
(). Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity. Neuron.
Applications
IHC, ICC, Histology
(). Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience.
Applications
IHC, ICC, Histology
(). D-LMBmap: a fully automated deep-learning pipeline for whole-brain profiling of neural circuitry. Nat Methods.
Applications
IF, Confocal Microscopy
(). Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis. Nat Cardiovasc Res.
Applications
IF, Confocal Microscopy
(). Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations. Cell Rep.
Applications
IHC, ICC, Histology
(). Sparse and stereotyped encoding implicates a core glomerulus for ant alarm behavior. Cell.
Applications
IHC, ICC, Histology
(). Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium. Microbiome.
Applications
IHC, ICC, Histology
(). Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart. Cell.
Applications
IF, Confocal Microscopy
(). Integrated cardio-behavioral responses to threat define defensive states. Nat Neurosci.
Applications
IHC, ICC, Histology
(). CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors. Neuron.
Applications
IF, Confocal Microscopy
(). Evolutionary assembly and disassembly of the mammalian sternum. Curr Biol.
Applications
IF, Confocal Microscopy
(). Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage. Cell Rep.
Applications
IF, Confocal Microscopy
(). Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity. iScience.
Applications
IF, Confocal Microscopy
(). Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow. Cell Metab.
Applications
IF, Confocal Microscopy
(). Regional and cell-type-specific afferent and efferent projections of the mouse claustrum. Cell Rep.
Applications
IF, Confocal Microscopy
(). Pathway-specific inputs to the superior colliculus support flexible responses to visual threat. Sci Adv.
Applications
IHC, ICC, Histology
(). Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis. Sci Rep.
Applications
IF, Confocal Microscopy
(). Nicotinic acetylcholine receptor signaling maintains epithelial barrier integrity. Elife.
Applications
Immuno-gold Electron Microscopy
(). DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons. Cell Rep.
Applications
IHC, ICC, Histology
(). Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). A STIM dependent dopamine-neuropeptide axis maintains the larval drive to feed and grow in Drosophila. PLoS Genet.
Applications
IHC, ICC, Histology
(). Acute manipulation and real-time visualization of membrane trafficking and exocytosis in Drosophila. 2023
Applications
IF, Confocal Microscopy
(). Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal. Cell Rep.
Applications
IF, Confocal Microscopy
(). Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence. Cell Rep Methods.
Applications
IHC, ICC, Histology
(). The Role of Genetically Distinct Central Amygdala Neurons in Appetitive and Aversive Responding Assayed with a Novel Dual Valence Operant Conditioning Paradigm. eNeuro.
Applications
IHC, ICC, Histology
(). COMBINe enables automated detection and classification of neurons and astrocytes in tissue-cleared mouse brains. Cell Rep Methods.
Applications
iDISCO
(). Deficiency of Cullin 3, a Protein Encoded by a Schizophrenia and Autism Risk Gene, Impairs Behaviors by Enhancing the Excitability of Ventral Tegmental Area (VTA) DA Neurons. J Neurosci.
Applications
IHC, ICC, Histology
(). Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell.
Applications
IF, Confocal Microscopy
(). Structural and functional map for forelimb movement phases between cortex and medulla. Cell.
Applications
IHC, ICC, Histology
(). CD34+ cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis. Sci Adv.
Applications
IF, Confocal Microscopy
(). Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver. Elife.
Applications
IF, Confocal Microscopy
(). Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice. Nat Commun.
Applications
IHC, ICC, Histology
(). FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers (Basel).
Applications
IHC, ICC, Histology
(). Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system. Cell Rep.
Applications
IHC, ICC, Histology
(). Neural tube-associated boundary caps are a major source of mural cells in the skin. Elife.
Applications
IF, Confocal Microscopy
(). Astrocyte growth is driven by the Tre1/S1pr1 phospholipid-binding G protein-coupled receptor. Neuron.
Applications
IHC, ICC, Histology
(). A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors. CRISPR J.
Applications
IHC, ICC, Histology
(). YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration. Cell Rep.
Applications
IF, Confocal Microscopy
(). Modular interneuron circuits control motion sensitivity in the mouse retina. Nat Commun.
Applications
IHC, ICC, Histology
(). Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience.
Applications
WB, IB, PCA
(). Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells. Sci Adv.
Applications
IF, Confocal Microscopy
(). Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer. Nat Metab.
Applications
IF, Confocal Microscopy
(). Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. Nature.
Applications
IHC, ICC, Histology
(). Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis. Nat Commun.
Applications
IHC, ICC, Histology
(). Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice. EBioMedicine.
Applications
IHC, ICC, Histology
(). NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells. Acta Neuropathol Commun.
Applications
WB, IB, PCA
(). CRH neurons in the lateral hypothalamic area regulate feeding behavior of mice. Cur Biol.
Applications
IF, Confocal Microscopy
(). Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila. Nat Commun.
Applications
IHC, ICC, Histology
(). Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy. Nat Commun.
Applications
IHC, ICC, Histology
(). Activity map of a cortico-cerebellar loop underlying motor planning. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands. Nat Commun.
Applications
IHC, ICC, Histology
(). A sign-inverted receptive field of inhibitory interneurons provides a pathway for ON-OFF interactions in the retina. Nat Commun.
Applications
IHC, ICC, Histology
(). Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks. Nat Commun.
Applications
IF, Confocal Microscopy
(). Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progression. EMBO J.
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). How variable progenitor clones construct a largely invariant neocortex. Natl Sci Rev.
Applications
IHC, ICC, Histology
(). δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte-neuron cadherin interactions. J Cell Biol.
Applications
IHC, ICC, Histology
(). Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo. JCI Insight.
Applications
ISH, FISH
(). Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control. Nat Commun.
Applications
IHC, ICC, Histology
(). Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice. Cell.
Applications
IHC, ICC, Histology
(). Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy. Cell Rep.
Applications
IHC, ICC, Histology
(). Repeated chemogenetic activation of dopaminergic neurons induces reversible changes in baseline and amphetamine-induced behaviors. Psychopharmacology (Berl).
Applications
IHC, ICC, Histology
(). Flk1 Deficiency and Hypoxia Synergistically Promote Endothelial Dysfunction, Vascular Remodeling, and Pulmonary Hypertension. Arterioscler Thromb Vasc Biol.
Applications
IHC, ICC, Histology
(). Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity. iScience.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). In Utero Electroporated Neurons for Medium-Throughput Screening of Compounds Regulating Neuron Morphology. eNeuro.
Applications
IHC, ICC, Histology
(). Alteration of endothelial permeability ensures cardiomyocyte survival from ischemic insult in the subendocardium of the heart. Exp Biol Med (Maywood).
Applications
IHC, ICC, Histology
(). Excitatory nucleo-olivary pathway shapes cerebellar outputs for motor control. Nat Neurosci.
Applications
IF, Confocal Microscopy; Immuno-EM
(). Brain-Wide Projections and Differential Encoding of Prefrontal Neuronal Classes Underlying Learned and Innate Threat Avoidance. J Neurosci.
Applications
IHC, ICC, Histology
(). Purkinje cell microzones mediate distinct kinematics of a single movement. Nat Commun.
Applications
iDISCO
(). Cortical regulation of neurogenesis and cell proliferation in the ventral subventricular zone. Cell Rep.
Applications
IF, Confocal Microscopy
(). Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice. Nat Commun.
Applications
IF, Confocal Microscopy
(). Caudal DMN neurons innervate the spleen and release CART peptide to regulate neuroimmune function. J Neuroinflammation.
Applications
IF, Confocal Microscopy
(). Ventromedial prefrontal neurons represent self-states shaped by vicarious fear in male mice. Nat Commun.
Applications
IHC, ICC, Histology
(). Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation. Sci Adv.
Applications
IF, Confocal Microscopy
(). Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses. Cell Rep.
Applications
IHC, ICC, Histology
(). Src family kinases engage differential pathways for encapsulation into extracellular vesicles. J Extracell Biol.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo. Proc Natl Acad Sci U S A.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Generation of a novel Stra8-driven Cre recombinase strain for use in pre-meiotic germ cells in mice†. Biol Reprod.
Applications
IF, Confocal Microscopy
(). Cerebellar contributions to a brainwide network for flexible behavior in mice. Commun Biol.
Applications
IHC, ICC, Histology
(). Liver and muscle circadian clocks cooperate to support glucose tolerance in mice. Cell Rep.
Applications
IF, Confocal Microscopy
(). Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression. Mol Metab.
Applications
IHC, ICC, Histology
(). Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration. Invest Opthalmol Vis Sci.
Applications
IHC, ICC, Histology
(). Genetic Tagging Uncovers a Robust, Selective Activation of the Thalamic Paraventricular Nucleus by Adverse Experiences Early in Life. Biol Psychiatry Glob Open Sci.
Applications
IHC, ICC, Histology
(). Parvalbumin-Positive Interneurons in the Medial Prefrontal Cortex Regulate Stress-Induced Fear Extinction Impairments in Male and Female Rats. J Neurosci.
Applications
IF, Confocal Microscopy
(). Fate mapping RNA-sequencing reveal Malat1 regulates Sca1+ progenitor cells to vascular smooth muscle cells transition in vascular remodeling. Cell Mol Life Sci.
Applications
IF, Confocal Microscopy
(). Optogenetic stimulation of mouse Hoxb8 microglia in specific regions of the brain induces anxiety, grooming, or both. Mol Psychiatry.
Applications
IHC, ICC, Histology
(). Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation. Nutrients.
Applications
IHC, ICC, Histology
(). Adaptation of a cervical bilateral contusive spinal cord injury for study of skilled forelimb function. Exp Neurol.
Applications
IHC, ICC, Histology
(). An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature.
Applications
IHC, ICC, Histology
(). Inducible Rbpms-CreERT2 Mouse Line for Studying Gene Function in Retinal Ganglion Cell Physiology and Disease. Cells.
Applications
IF, Confocal Microscopy
(). Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1. Mol Cell Neurosci.
Applications
IHC, ICC, Histology
(). Multilineage commitment of Sca-1+ cells in reshaping vein grafts. Theranostics.
Applications
IF, Confocal Microscopy
(). Controlled Tau Cleavage in Cells Reveals Abnormal Localizations of Tau Fragments. Neuroscience.
Applications
WB, IB, PCA
(). Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cord. Elife.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Functional ProTracer identifies patterns of cell proliferation in tissues and underlying regulatory mechanisms. NPJ Regen Med.
Applications
IF, Confocal Microscopy
(). Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing. Nat Biotechnol.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Inducible generalized activation of hSTING-N154S expression in mice leads to lethal hypercytokinemia: a model for "cytokine storm". J Leukoc Biol.
Applications
IHC, ICC, Histology
(). Neuronal and astrocytic contributions to Huntington's disease dissected with zinc finger protein transcriptional repressors. Cell Rep.
Applications
IHC, ICC, Histology
(). Astrocyte-neuron subproteomes and obsessive-compulsive disorder mechanisms. Nature.
Applications
IHC, ICC, Histology
(). Identifying an oligodendrocyte enhancer that regulates Olig2 expression. Hum Mol Genet.
Applications
IF, Confocal Microscopy
(). Rescue of glutaric aciduria type I in mice by liver-directed therapies. Sci Transl Med.
Applications
IHC, ICC, Histology
(). Engineered tRNAs suppress nonsense mutations in cells and in vivo. Nature.
Applications
IF, Confocal Microscopy
(). Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Sci Adv.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology; WB, IB, PCA
(). The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice. Front Endocrinol (Lausanne).
Applications
IHC, ICC, Histology
(). Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b-mediated chromatin demethylation. EMBO J.
Applications
IF, Confocal Microscopy
(). Glioma synapses recruit mechanisms of adaptive plasticity. Nature.
Applications
IF, Confocal Microscopy
(). Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia. Cell Mol Gastroenterol Hepatol.
Applications
IF, Confocal Microscopy
(). Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled. Elife.
Applications
IF, Confocal Microscopy
(). A brainstem circuit for nausea suppression. Cell Rep.
Applications
IHC, ICC, Histology
(). A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus. Curr Biol.
Applications
Undefined
(). A dentate gyrusdentate gyrus-CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. Elife.
Applications
IHC, ICC, Histology
(). A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles. Pharmaceutics.
Applications
WB, IB, PCA
(). A general approach for engineering RTKs optically controlled with far-red light. Nat Methods.
Applications
Undefined
(). A light-gated transcriptional recorder for detecting cell-cell contacts. Elife.
Applications
IF, Confocal Microscopy
(). A novel spinal neuron connection for heat sensation. Neuron.
Applications
Undefined
(). A persistent behavioral state enables sustained predation of humans by mosquitoes. Elife.
Applications
IF, Confocal Microscopy
(). Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. J Cereb Blood Flow Metab.
Applications
IHC, ICC, Histology
(). Activation of LH GABAergic inputs counteracts fasting‐induced changes in tVTA/RMTG neurons. J Physiol.
Applications
Undefined
(). Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion. Front Pharmacol.
Applications
IHC, ICC, Histology
(). Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture. STAR Protoc.
Applications
IF, Confocal Microscopy
(). Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex. Cells.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells. J Cereb Blood Flow Metab.
Applications
Undefined
(). CENP-N promotes the compaction of centromeric chromatin. Nat Struct Mol Biol.
Applications
IF, Confocal Microscopy
(). Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer Res.
Applications
IHC, ICC, Histology
(). Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate. Neurosci Res.
Applications
Undefined
(). Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell.
Applications
Undefined
(). Deciphering the origins and fates of steroidogenic lineages in the mouse testis. Cell Rep.
Applications
IF, Confocal Microscopy
(). Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction. Nat Commun.
Applications
IHC, ICC, Histology
(). Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells. Elife.
Applications
IHC, ICC, Histology
(). Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo. J Biol Chem.
Applications
IF, Confocal Microscopy
(). Dual-functional hydrogel system for spinal cord regeneration with sustained release of arylsulfatase B alleviates fibrotic microenvironment and promotes axonal regeneration. Biomaterials.
Applications
IHC, ICC, Histology
(). Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice. Front Cell Dev Biol.
Applications
WB, IB, PCA
(). Generation of Piezo1‐CreER transgenic mice for visualization and lineage tracing of mechanical force responsive cells in vivo. Genesis.
Applications
Undefined
(). Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis. Cell Res.
Applications
Undefined
(). Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart. J Cell Biol.
Applications
Undefined
(). Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. Elife.
Applications
IF, Confocal Microscopy
(). Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury. Exp Neurol.
Applications
IF, Confocal Microscopy
(). Mouse placenta fetal macrophages arise from endothelial cells outside the placenta. Dev Cell.
Applications
IF, Confocal Microscopy
(). Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations. Elife.
Applications
IF, Confocal Microscopy
(). PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma. Cancer Res.
Applications
IF, Confocal Microscopy
(). Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis. Nat Neurosci.
Applications
IF, Confocal Microscopy
(). Hedgehog regulation of epithelial cell state and morphogenesis in the larynx. Elife.
Applications
IF, Confocal Microscopy
(). Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics. Cell Discov.
Applications
IF, Confocal Microscopy
(). Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer. Nat Cell Biol.
Applications
ISH, FISH
(). Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia. Front Cell Neurosci.
Applications
IHC, ICC, Histology
(). Adult Camk2a gene reinstatement restores the learning and plasticity deficits of Camk2a knockout mice. iScience.
Applications
IHC, ICC, Histology
(). Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease. Cell Rep.
Applications
IHC, ICC, Histology
(). Neuronal hyperactivity-induced oxidant stress promotes in vivo α-synuclein brain spreading. Sci Adv.
Applications
IHC, ICC, Histology
(). Spatial and temporal control of expression with light-gated LOV-LexA. G3 (Bethesda).
Applications
IF, Confocal Microscopy
(). DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential. Dev Cell.
Applications
IF, Confocal Microscopy; ISH, FISH
(). Transcriptional responses to injury of regenerative lung alveolar epithelium. iScience
Applications
IF, Confocal Microscopy
(). Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). The whisking oscillator circuit. Nature.
Applications
IHC, ICC, Histology
(). Stress-driven potentiation of lateral hypothalamic synapses onto ventral tegmental area dopamine neurons causes increased consumption of palatable food. Nat Commun.
Applications
IF, Confocal Microscopy
(). Patterned cPCDH expression regulates the fine organization of the neocortex. Nature.
Applications
IF, Confocal Microscopy
(). Bacteria-Derived Peptidoglycan Triggers a Noncanonical Nuclear Factor-κB-Dependent Response in Drosophila Gustatory Neurons. J Neurosci.
Applications
IHC, ICC, Histology
(). Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses. Nat Commun.
Applications
IF, Confocal Microscopy
(). Niche-mediated repair of airways is directed in an occupant-dependent manner. Cell Rep.
Applications
IF, Confocal Microscopy
(). Central role of Prominin-1 in lipid rafts during liver regeneration. Nat Commun.
Applications
IF, Confocal Microscopy
(). Rehabilitation combined with neural progenitor cell grafts enables functional recovery in chronic spinal cord injury. JCI Insight.
Applications
IHC, ICC, Histology
(). Tagging active neurons by soma-targeted Cal-Light. Nat Commun.
Applications
IF, Confocal Microscopy
(). Brainstem ADCYAP1+ neurons control multiple aspects of sickness behaviour. Nature.
Applications
IF, Confocal Microscopy
(). Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad. Sci Adv.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum. Int J Mol Sci.
Applications
WB, IB, PCA
(). Organization of Cortical and Thalamic Input to Inhibitory Neurons in Mouse Motor Cortex. J Neurosci.
Applications
IHC, ICC, Histology
(). Association of variants in the KIF1A gene with amyotrophic lateral sclerosis. Transl Neurodegener.
Applications
IF, Confocal Microscopy
(). Club cells employ regeneration mechanisms during lung tumorigenesis. Nature Communications
Applications
IF, Confocal Microscopy
(). Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus. Scientific Reports
Applications
IF, Confocal Microscopy
(). Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2. ELife
Applications
Light-Sheet Microscopy (LSM); Other
(). Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway. Proceedings of the National Academy of Sciences of the United States of America
Applications
IHC, ICC, Histology
(). PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis. International Journal of Biological Sciences
Applications
IHC, ICC, Histology
(). Origin and function of activated fibroblast states during zebrafish heart regeneration. Nature Genetics
Applications
IF, Confocal Microscopy
(). Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability. Scientific Reports
Applications
IF, Confocal Microscopy
(). The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration. Journal of Neuroinflammation
Applications
IF, Confocal Microscopy
(). STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Science Alliance
Applications
IF, Confocal Microscopy
(). Intersectional mapping of multi-transmitter neurons and other cell types in the brain. Cell Reports
Applications
IHC, ICC, Histology
(). Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents. Development (Cambridge, England)
Applications
IF, Confocal Microscopy
(). PIEZO1 transduces mechanical itch in mice. Nature
Applications
IHC, ICC, Histology
(). Selectively Imaging Cranial Sensory Ganglion Neurons Using AAV-PHP.S. ENeuro
Applications
IHC, ICC, Histology
(). Co-targeting B-RAF and PTEN Enables Sensory Axons to Regenerate Across and Beyond the Spinal Cord Injury. Frontiers in Molecular Neuroscience
Applications
IHC, ICC, Histology
(). Multi-ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy. Cancer Reports (Hoboken, N.J.)
Applications
IHC, ICC, Histology
(). Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. ELife
Applications
IF, Confocal Microscopy
(). Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition. Cell and Tissue Research
Applications
IF, Confocal Microscopy
(). Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. Front Oncol.
Applications
IF, Confocal Microscopy
(). Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun.
Applications
IHC, ICC, Histology
(). Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses. Int J Mol Sci.
Applications
WB, IB, PCA
(). Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth. Sci Adv.
Applications
IF, Confocal Microscopy
(). Medullary kappa-opioid receptor neurons inhibit pain and itch through a descending circuit. Brain.
Applications
Undefined
(). Myosin V facilitates polarised E‐cadherin secretion. Traffic.
Applications
IHC, ICC, Histology
(). Neuromodulatory control of inhibitory network arborization in the developing postnatal neocortex. Sci Adv.
Applications
IHC, ICC, Histology
(). Netrin1 and reelin signaling are required for the migration of anterolateral system neurons in the embryonic spinal cord. Pain.
Applications
Undefined
(). Perirhinal Cortex LTP Does Not Require Astrocyte BDNF-TrkB Signaling. Cells.
Applications
IHC, ICC, Histology
(). Processing of information from the parafascicular nucleus of the thalamus through the basal ganglia. J Neurosci Res.
Applications
IF, Confocal Microscopy
(). Postnatal state transition of cardiomyocyte as a primary step in heart maturation. Protein Cell.
Applications
IF, Confocal Microscopy
(). Proton-gated anion transport governs macropinosome shrinkage. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Regulation of developmental hierarchy in Drosophila neural stem cell tumors by COMPASS and Polycomb complexes. Sci Adv.
Applications
IF, Confocal Microscopy
(). Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity. Elife.
Applications
IHC, ICC, Histology
(). Robust and sensitive in situ RNA detection using Yn-situ. Cell Rep Methods.
Applications
IF, Confocal Microscopy
(). Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development. Cell Rep.
Applications
IF, Confocal Microscopy
(). Silencing of amygdala circuits during sepsis prevents the development of anxiety-related behaviours. Brain.
Applications
IHC, ICC, Histology
(). Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nat Neurosci.
Applications
Undefined
(). Sticks and Stones, a conserved cell surface ligand for the Type IIa RPTP Lar, regulates neural circuit wiring in Drosophila. Elife.
Applications
IHC, ICC, Histology
(). Strong Aversive Conditioning Triggers a Long-Lasting Generalized Aversion. Front Cell Neurosci.
Applications
IHC, ICC, Histology
(). Subcellular proteomics of dopamine neurons in the mouse brain. Elife.
Applications
IHC, ICC, Histology
(). Structural and Functional Support by Left Atrial Appendage Transplant to the Left Ventricle after a Myocardial Infarction. Int J Mol Sci.
Applications
iDISCO
(). The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity. J Cell Sci.
Applications
IF, Confocal Microscopy
(). The essential M. tuberculosis Clp protease is functionally asymmetric in vivo. Sci Adv.
Applications
WB, IB, PCA
(). The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia.
Applications
IHC, ICC, Histology
(). Targeting thalamic circuits rescues motor and mood deficits in PD mice. Nature.
Applications
Undefined
(). Transcriptional regulation of neural stem cell expansion in the adult hippocampus. Elife.
Applications
ISH, FISH
(). Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nat Cell Biol.
Applications
Undefined
(). Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles. J Control Release.
Applications
IHC, ICC, Histology
(). An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury. Neuron.
Applications
IHC, ICC, Histology
(). Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Nat Protoc.
Applications
Undefined
(). The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. Acta Neuropathol Commun.
Applications
IHC, ICC, Histology
(). Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality. Acta Physiol (Oxf).
Applications
ISH, FISH
(). Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs. Chem Phys Lipids.
Applications
Undefined
(). Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes. J Extracell Vesicles.
Applications
IF, Confocal Microscopy
(). The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis. J Biol Chem.
Applications
IHC, ICC, Histology
(). Adaptive differentiation promotes intestinal villus recovery. Dev Cell.
Applications
Undefined
(). Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses. JCI Insight.
Applications
IHC, ICC, Histology
(). IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation. Nat Immunol.
Applications
Undefined
(). The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development
Applications
IF, Confocal Microscopy
(). Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells. Immunity.
Applications
Undefined
(). Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab.
Applications
IF, Confocal Microscopy
(). SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport. Dev Cell.
Applications
Undefined
(). Subfornical organ interleukin 1 receptor: a novel regulator of spontaneous and conditioned fear associated behaviors in mice. Brain Behav Immun.
Applications
IHC, ICC, Histology
(). Combined Kelch-Like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice. J Am Soc Nephrol.
Applications
Undefined
(). Subcellular and regional localization of mRNA translation in midbrain dopamine neurons. Cell Rep.
Applications
IHC, ICC, Histology
(). Twist regulates Yorkie activity to guide lineage reprogramming of syncytial alary muscles. Cell Rep.
Applications
IF, Confocal Microscopy
(). Genome Editing with AAV-BR1-CRISPR in Postnatal Mouse Brain Endothelial Cells. Int J Biol Sci.
Applications
IHC, ICC, Histology
(). Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei. Nucleic Acids Res.
Applications
IP, Co-IP; ISH, FISH
(). Median raphe region GABAergic neurons contribute to social interest in mouse. Life Sci.
Applications
IHC, ICC, Histology
(). High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells. STAR Protoc.
Applications
IF, Confocal Microscopy
(). AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Molecular Therapy
Applications
IF, Confocal Microscopy
(). Iron contributes to photoreceptor degeneration and Müller glia proliferation in the zebrafish light-treated retina. Exp Eye Res.
Applications
Undefined
(). DRGquant: A new modular AI-based Pipeline for 3D Analysis of the DRG. J Neurosci Methods.
Applications
IHC, ICC, Histology
(). Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo. J Cell Biol.
Applications
Undefined
(). A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking. Neuron.
Applications
IF, Confocal Microscopy
(). Activation, but not inhibition, of the indirect pathway disrupts choice rejection in a freely moving, multiple-choice foraging task. Cell Rep.
Applications
IHC, ICC, Histology
(). Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4. Dev Cell.
Applications
IF, Confocal Microscopy
(). Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition. Dev Cell.
Applications
IF, Confocal Microscopy
(). Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41 dTomato-Cre. Front Immunol.
Applications
IF, Confocal Microscopy
(). Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood-brain barrier in rodents and primates. Nat Biomed Eng.
Applications
IF, Confocal Microscopy
(). Anatomical Development of the Cerebellothalamic Tract in Embryonic Mice. Cells.
Applications
iDISCO; IF, Confocal Microscopy; IHC, ICC, Histology
(). A quantitative 3D intravital look at the juxtaglomerular renin-cell-niche reveals an individual intra/extraglomerular feedback system. Front Physiol.
Applications
IF, Confocal Microscopy
(). CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth. Development.
Applications
IHC, ICC, Histology
(). Noradrenergic consolidation of social recognition memory is mediated by β-arrestin-biased signaling in the mouse prefrontal cortex. Commun Biol.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Molecular signatures and cellular diversity during mouse habenula development. Cell Rep.
Applications
iDISCO
(). Oral Sensory Neurons of the Geniculate Ganglion That Express Tyrosine Hydroxylase Comprise a Subpopulation That Contacts Type II and Type III Taste Bud Cells. eNeuro.
Applications
IF, Confocal Microscopy
(). Somatostatin interneurons exhibit enhanced functional output and resilience to axotomy after mild traumatic brain injury. Neurobiol Dis.
Applications
IHC, ICC, Histology
(). Single Nuclei Analyses Reveal Transcriptional Profiles and Marker Genes for Diverse Supraspinal Populations. J Neurosci.
Applications
IHC, ICC, Histology
(). Different inflammation responses modulate Müller glia proliferation in the acute or chronically damaged zebrafish retina. Front Cell Dev Biol.
Applications
IHC, ICC, Histology
(). In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein. Adv Genet (Hoboken).
Applications
TEM; WB, IB, PCA; Dot Blot Assay
(). Evaluation and manipulation of tissue and cellular distribution of cardiac progenitor cell-derived extracellular vesicles. Front Pharmacol.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics. Biomaterials.
Applications
IHC, ICC, Histology
(). Characterization of non-alpha retinal ganglion cell injury responses reveals a possible block to restoring ipRGC function. Exp Neurol.
Applications
IHC, ICC, Histology
(). Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy. STAR Protoc.
Applications
IHC, ICC, Histology
(). C-low threshold mechanoreceptor activation becomes sufficient to trigger affective pain in spinal cord-injured mice in association with increased respiratory rates. Front Integr Neurosci.
Applications
IHC, ICC, Histology
(). Origin of thyrotropin-releasing hormone neurons that innervate the tuberomammillary nuclei. Brain Struct Funct.
Applications
IHC, ICC, Histology
(). Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis. PLoS Comput Biol.
Applications
IHC, ICC, Histology
(). Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer. Mol Biol Cell.
Applications
IHC, ICC, Histology
(). Generation of Plvap-CreER and Car4-CreER for genetic targeting of distinct lung capillary populations. J Genet Genomics.
Applications
IHC, ICC, Histology
(). Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney. Sci Rep.
Applications
IF, Confocal Microscopy
(). Molecular identity of proprioceptor subtypes innervating different muscle groups in mice. Nat Commun.
Applications
IHC, ICC, Histology
(). Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset. Sci Adv.
Applications
IHC, ICC, Histology
(). Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Sci Adv.
Applications
IF, Confocal Microscopy
(). Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas. Dis Model Mech.
Applications
IF, Confocal Microscopy
(). TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife.
Applications
IF, Confocal Microscopy
(). Dynamic cell cycle-dependent phosphorylation modulates CENP-L-CENP-N centromere recruitment. Mol Biol Cell.
Applications
IF, Confocal Microscopy
(). Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry. Dev Cell.
Applications
IF, Confocal Microscopy
(). Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel. Frontiers in Neuroscience
Applications
IHC, ICC, Histology
(). A deep learning approach to identifying immunogold particles in electron microscopy images. Scientific Reports
Applications
Immuno-EM
(). CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge. International Journal of Molecular Sciences
Applications
Other
(). Drp1 is required for AgRP neuronal activity and feeding. ELife
Applications
Immuno-EM
(). Control of feeding by Piezo-mediated gut mechanosensation in Drosophila. ELife
Applications
IHC, ICC, Histology
(). Widespread labeling and genomic editing of the fetal central nervous system by in utero CRISPR AAV9-PHP.eB administration. Development (Cambridge, England)
Applications
IHC, ICC, Histology
(). Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). Decoding neuronal composition and ontogeny of individual hypothalamic nuclei. Neuron.
Applications
IF, Confocal Microscopy
(). Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity. Genes Cells.
Applications
IF, Confocal Microscopy
(). Repetitive injury and absence of monocytes promote astrocyte self‐renewal and neurological recovery. Glia.
Applications
IHC, ICC, Histology
(). Increased Callosal Connectivity in Reeler Mice Revealed by Brain-Wide Input Mapping of VIP Neurons in Barrel Cortex. Cereb Cortex.
Applications
ISH, FISH
(). Activation of preoptic tachykinin 1 neurons promotes wakefulness over sleep and volatile anesthetic-induced unconsciousness. Curr Biol.
Applications
IHC, ICC, Histology
(). CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion Cell Stem Cell.
Applications
WB, IB, PCA
(). Stromal SOX2 upregulation promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population. Dev Cell.
Applications
IF, Confocal Microscopy
(). Area postrema cell types that mediate nausea-associated behaviors. Neuron.
Applications
IHC, ICC, Histology
(). Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells. Stem Cell Reports
Applications
Undefined
(). A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis. Cell Rep.
Applications
IHC, ICC, Histology
(). Using a reporter mouse to map known and novel sites of GLP-1 receptor expression in peripheral tissues of male mice. Endocrinology.
Applications
Undefined
(). Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. Elife
Applications
WB, IB, PCA
(). Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res
Applications
WB, IB, PCA
(). PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat. Cell Rep.
Applications
IF, Confocal Microscopy
(). Morphine acts on spinal dynorphin neurons to cause itch through disinhibition. Sci Transl Med.
Applications
Undefined
(). Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex. Nat Commun.
Applications
WB, IB, PCA
(). Hippocampal neurons respond to brain activity with functional hypoxia. Mol Psychiatry.
Applications
IF, Confocal Microscopy
(). A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell.
Applications
Undefined
(). Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain. Cell Rep.
Applications
IHC, ICC, Histology
(). Olig3 regulates early cerebellar development. Elife
Applications
IF, Confocal Microscopy
(). Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas. Cell Rep.
Applications
IF, Confocal Microscopy
(). Intravital microscopy of dynamic single-cell behavior in mouse mammary tissue. Nat Protoc.
Applications
Undefined
(). Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation. Nat Commun.
Applications
IF, Confocal Microscopy
(). Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum. PLoS Biol.
Applications
IHC, ICC, Histology
(). Hydrogels Containing Gradients in Vascular Density Reveal Dose-Dependent Role of Angiocrine Cues on Stem Cell Behavior. Advanced Functional Materials
Applications
IHC, ICC, Histology
(). An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis. Science Advances
Applications
WB, IB, PCA
(). Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model. Cells
Applications
IHC, ICC, Histology
(). Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release. Brain Sciences
Applications
IHC, ICC, Histology
(). Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning. Cell Reports
Applications
IHC, ICC, Histology
(). Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling. ELife
Applications
IF, Confocal Microscopy
(). Functional expression of TMEM16A in taste bud cells. The Journal of Physiology
Applications
IHC, ICC, Histology
(). Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature Protocols
Applications
IF, Confocal Microscopy
(). Optogenetic axon guidance in embryonic zebrafish. Star Protocols
Applications
IHC, ICC, Histology
(). The bone microenvironment invigorates metastatic seeds for further dissemination. Cell.
Applications
IF, Confocal Microscopy
(). Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators. Elife.
Applications
WB, IB, PCA
(). The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. J Neurosci Res.
Applications
IHC, ICC, Histology
(). Cascade diversification directs generation of neuronal diversity in the hypothalamus. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia. Stem Cells Transl Med.
Applications
IF, Confocal Microscopy
(). MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development. Front Neurosci.
Applications
IF, Confocal Microscopy
(). NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature.
Applications
Undefined
(). Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors. Neuron.
Applications
Undefined
(). Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions. Elife.
Applications
IHC, ICC, Histology
(). Analysis of growth cone extension in standardized coordinates highlights self-organization rules during wiring of the Drosophila visual system. PLoS Genet.
Applications
IHC, ICC, Histology
(). Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism. Prog Neurobiol.
Applications
IF, Confocal Microscopy
(). Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol.
Applications
IF, Confocal Microscopy
(). VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol.
Applications
WB, IB, PCA
(). Protein-retention expansion microscopy for visualizing subcellular organelles in fixed brain tissue. J Neurosci Methods.
Applications
IHC, ICC, Histology
(). Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder. Cell Rep.
Applications
IHC, ICC, Histology
(). SARS-CoV-2 infection in the mouse olfactory system. Cell Discov.
Applications
IF, Confocal Microscopy
(). Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Cell Rep.
Applications
IHC, ICC, Histology
(). A genetically defined insula-brainstem circuit selectively controls motivational vigor. Cell.
Applications
Undefined
(). Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis. Cell Rep.
Applications
IHC, ICC, Histology
(). Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proc Natl Acad Sci USA
Applications
IHC, ICC, Histology
(). Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature.
Applications
IF, Confocal Microscopy
(). The Coiled‐Coil Forming Peptide (KVSALKE)5 Is a Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Adv Healthc Mater.
Applications
Undefined
(). Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis. Nat Aging.
Applications
IF, Confocal Microscopy; TUNEL
(). Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities. PLoS One
Applications
IF, Confocal Microscopy
(). Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair. Cell Calcium.
Applications
Undefined
(). Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. Nat Commun.
Applications
IF, Confocal Microscopy
(). Inactivation of Hedgehog signal transduction in adult astrocytes results in region-specific blood–brain barrier defects. Proc Natl Acad Sci USA
Applications
IHC, ICC, Histology
(). Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev.
Applications
IHC, ICC, Histology
(). Covert capture and attenuation of a hippocampus-dependent fear memory. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice. Science.
Applications
IHC, ICC, Histology
(). Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI Insight.
Applications
IF, Confocal Microscopy
(). Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron.
Applications
IHC, ICC, Histology
(). Quantification of adipocyte numbers following adipose tissue remodeling. Cell Rep.
Applications
IHC, ICC, Histology
(). Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol.
Applications
Undefined
(). Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes. J Cell Biol.
Applications
Undefined
(). Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma. Nat Cancer.
Applications
Undefined
(). Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. Nat Commun.
Applications
IF, Confocal Microscopy
(). Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep.
Applications
IF, Confocal Microscopy
(). Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Sci Adv.
Applications
IHC, ICC, Histology
(). Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Rep.
Applications
IHC, ICC, Histology
(). Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis. Sci Adv.
Applications
IHC, ICC, Histology
(). IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Sci Adv.
Applications
IHC, ICC, Histology
(). Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory. Sci Immunol.
Applications
Undefined
(). Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production. iScience.
Applications
IF, Confocal Microscopy
(). Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol.
Applications
IHC, ICC, Histology
(). The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. Dev Cell.
Applications
WB, IB, PCA
(). The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell.
Applications
IHC, ICC, Histology
(). Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv.
Applications
IF, Confocal Microscopy
(). Constructing an adult orofacial premotor atlas in Allen mouse CCF. Elife
Applications
IHC, ICC, Histology
(). Pancreatic β-cells communicate with vagal sensory neurons. Gastroenterology
Applications
Undefined
(). Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metab.
Applications
IF, Confocal Microscopy
(). Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. J Exp Med.
Applications
Undefined
(). ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain. Sci Adv.
Applications
IF, Confocal Microscopy
(). Transcriptional profiling of sequentially generated septal neuron fates. Elife.
Applications
IF, Confocal Microscopy
(). The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development
Applications
IHC, ICC, Histology; Other
(). Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states. Sci Rep.
Applications
IHC, ICC, Histology
(). HepaCAM controls astrocyte self-organization and coupling. Neuron.
Applications
IF, Confocal Microscopy
(). Cell of origin influences pancreatic cancer subtype. Cancer Discov.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4. EMBO J.
Applications
IHC, ICC, Histology
(). Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun.
Applications
IF, Confocal Microscopy
(). A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers. Nat Cell Biol.
Applications
Undefined
(). An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife.
Applications
IHC, ICC, Histology
(). Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. J Exp Med.
Applications
IF, Confocal Microscopy
(). Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Phychiatry.
Applications
IHC, ICC, Histology
(). Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells. iScience.
Applications
IF, Confocal Microscopy
(). Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting. Cell Rep.
Applications
IHC, ICC, Histology; Other
(). Genetically identified amygdala–striatal circuits for valence-specific behaviors. Nat Neurosci.
Applications
Undefined
(). A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol.
Applications
IHC, ICC, Histology
(). Ronin governs the metabolic capacity of the embryonic lineage for post‐implantation development. EMBO Reports
Applications
IF, Confocal Microscopy
(). Microglia sense neuronal activity via GABA in the early postnatal hippocampus. Cell Rep.
Applications
IHC, ICC, Histology
(). Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biol Open
Applications
IF, Confocal Microscopy
(). Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Mol Metab.
Applications
IF, Confocal Microscopy
(). Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes. Mol Biol Cell.
Applications
IF, Confocal Microscopy
(). I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. Development
Applications
IF, Confocal Microscopy
(). RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. PLoS Biol.
Applications
IHC, ICC, Histology
(). Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice. Endocrinology
Applications
Undefined
(). Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. Elife.
Applications
IHC, ICC, Histology
(). Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors. Elife.
Applications
IHC, ICC, Histology
(). Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. Nat Commun.
Applications
IHC, ICC, Histology
(). Tools for efficient analysis of neurons in a 3D reference atlas of whole mouse spinal cord. Cell Rep Methods.
Applications
IHC, ICC, Histology
(). Parallel processing by distinct classes of principal neurons in the olfactory cortex. Elife.
Applications
IHC, ICC, Histology
(). Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development. EMBO Rep.
Applications
WB, IB, PCA
(). Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Cell Rep.
Applications
IHC, ICC, Histology; Other
(). Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention. Commun Biol.
Applications
IHC, ICC, Histology
(). Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. Circulation.
Applications
IF, Confocal Microscopy
(). Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex. Elife.
Applications
IF, Confocal Microscopy
(). Functional diversity for body actions in the mesencephalic locomotor region. Cell.
Applications
IHC, ICC, Histology
(). Derivation of airway basal stem cells from human pluripotent stem cells. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Identifying oligodendrocyte enhancers governing Plp1 expression. Hum Mol Genet.
Applications
IF, Confocal Microscopy
(). Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. Cell Rep.
Applications
IHC, ICC, Histology
(). Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron.
Applications
IHC, ICC, Histology
(). Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol.
Applications
IHC, ICC, Histology
(). Fibroblast dedifferentiation as a determinant of successful regeneration. Dev Cell.
Applications
IF, Confocal Microscopy
(). Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum. Nat Commun.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli. Neurobiol Stress.
Applications
IHC, ICC, Histology
(). Mitochondrial ROS induced lysosomal dysfunction and autophagy impairment in an animal model of congenital hereditary endothelial dystrophy. Invest Ophthalmol Vis Sci.
Applications
IHC, ICC, Histology
(). TMEM16A and TMEM16B modulate pheromone-evoked action potential firing in mouse vomeronasal sensory neurons. eNeuro.
Applications
IHC, ICC, Histology
(). STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. J Neurosci
Applications
Undefined
(). TGFβ signaling activated by cancer-associated fibroblasts determines the histological signature of lung adenocarcinoma. Cancer Res.
Applications
IF, Confocal Microscopy
(). Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice. J Mol Endocrinol.
Applications
IHC, ICC, Histology
(). Live-Cell Imaging Technique to Visualize DAMPs Release During Regulated Cell Death. Methods Mol Biol.
Applications
Undefined
(). Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice. PLoS One
Applications
IHC, ICC, Histology
(). Modulation of both intrinsic and extrinsic factors additively promotes rewiring of corticospinal circuits after spinal cord injury. J Neurosci.
Applications
Undefined
(). NPY released from GABA neurons of the dentate gyrus specially reduces contextual fear without affecting cued or trace fear. Front Synaptic Neurosci.
Applications
IHC, ICC, Histology
(). Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation. Front Cell Dev Biol.
Applications
IHC, ICC, Histology
(). The impact of SST and PV interneurons on nonlinear synaptic integration in the neocortex. eNeuro.
Applications
IF, Confocal Microscopy
(). Experience-dependent inhibitory plasticity is mediated by CCK+ basket cells in the developing dentate gyrus. J Neurosci.
Applications
IHC, ICC, Histology
(). Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution. Methods Mol Biol.
Applications
Undefined
(). An Optimized Whole‐Mount Immunofluorescence Method for Shoot Apices. Curr Protoc.
Applications
Undefined
(). Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation In Vivo with CalExflox Mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1‐transgenic mice. Glia.
Applications
IHC, ICC, Histology
(). Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson's disease and OCD-like behaviors in mice. Mol Psychiatry.
Applications
IHC, ICC, Histology
(). Level of hM4D (Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus. eNeuro.
Applications
IHC, ICC, Histology
(). Reconsidering the border between the visual and posterior parietal cortex of mice. Cereb Cortex.
Applications
IHC, ICC, Histology
(). Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell Rep.
Applications
IHC, ICC, Histology
(). Mouse models for studying hippocampal adult neural stem cell biology. Methods Mol Biol.
Applications
Undefined
(). Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol.
Applications
IF, Confocal Microscopy
(). An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish. Elife.
Applications
IHC, ICC, Histology
(). Río-Hortega's drawings revisited with fluorescent protein defines a cytoplasm-filled channel system of CNS myelin. J Anat.
Applications
Immuno-EM
(). An inhibitory hippocampal-thalamic pathway modulates remote memory retrieval. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird. Nat Commun.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Early stem cell aging in the mature brain. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Photoreceptor nanotubes mediate the in vivo exchange of intracellular material. EMBO J.
Applications
IF, Confocal Microscopy
(). GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum. eNeuro
Applications
IF, Confocal Microscopy
(). Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun.
Applications
IF, Confocal Microscopy
(). Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol.
Applications
IHC, ICC, Histology
(). Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep.
Applications
IHC, ICC, Histology
(). Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter. IBRO Rep.
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
(). Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol.
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
(). The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse. Cell Rep.
Applications
IF, Confocal Microscopy
(). Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. Neural Dev.
Applications
IF, Confocal Microscopy
(). Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea. Sci Rep.
Applications
IF, Confocal Microscopy
(). Transcriptional activities of human elongation factor-1α and cytomegalovirus promoter in transgenic dogs generated by somatic cell nuclear transfer. PLoS One.
Applications
IHC, ICC, Histology
(). Indian hedgehog in craniofacial neural crest cells links to skeletal malocclusion by regulating associated cartilage formation and gene expression. FASEB J.
Applications
Undefined
(). Yolk-sac-derived macrophages progressively expand in the mouse kidney with age. Elife
Applications
IF, Confocal Microscopy
(). Somatostatin neurons of the bed nucleus of stria terminalis enhance associative fear memory consolidation in mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes. Cell Struct Funct.
Applications
WB, IB, PCA
(). Activity-dependent dendritic elaboration requires Pten. Neurobiol Dis.
Applications
IHC, ICC, Histology
(). Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Effects of nectin-3 misexpression on dendritic spine density during the postnatal development of layer 2/3 cortical neurons. Neural Dev
Applications
IHC, ICC, Histology
(). Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol.
Applications
IF, Confocal Microscopy
(). Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. Neural Dev.
Applications
IHC, ICC, Histology
(). Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology
Applications
IHC, ICC, Histology
(). Neurogenic Niche Conversion Strategy Induces Migration and Functional Neuronal Differentiation of Neural Precursor Cells Following Brain Injury. Stem Cells Dev.
Applications
IF, Confocal Microscopy
(). Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors. Cell Mol Life Sci.
Applications
IF, Confocal Microscopy
(). A Feedforward Circuit Regulates Action Selection of Pre-mating Courtship Behavior in Female Drosophila. Curr Biol.
Applications
IHC, ICC, Histology
(). Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors. Neuron
Applications
IHC, ICC, Histology
(). Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. J Comp Neurol.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Front Mol Neurosci.
Applications
IHC, ICC, Histology
(). Development and characterization of an Otp conditional loss of function allele. Genesis
Applications
IF, Confocal Microscopy
(). Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell.
Applications
IF, Confocal Microscopy
(). Placental gene editing via trophectoderm-specific Tat-Cre/loxP recombination. Development
Applications
Undefined
(). Microstimulation of primate neocortex targeting striosomes induces negative decision-making. Eur J Neurosci.
Applications
Undefined
(). Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. J Exp Med.
Applications
IF, Confocal Microscopy
(). Genetic ablation of SOD1G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression. bioRxiv
Applications
IF, Confocal Microscopy
(). Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. Neurogastroenterol Motil. Neurogastroenterol Motil.
Applications
IF, Confocal Microscopy
(). Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer
Applications
Undefined
(). Astrocytes shape the plastic response of adult cortical neurons to vision loss. Glia
Applications
IHC, ICC, Histology
(). Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron
Applications
Undefined
(). Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus. bioRxiv
Applications
IHC, ICC, Histology
(). Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis. Cell Stem Cell.
Applications
IF, Confocal Microscopy
(). Generation of transgenic mice that conditionally express microRNA miR-145. Genesis.
Applications
IHC, ICC, Histology
(). In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Brain
Applications
IHC, ICC, Histology
(). Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Curr Biol.
Applications
IF, Confocal Microscopy
(). A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus. ELife
Applications
IHC, ICC, Histology
(). Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner. Elife
Applications
WB, IB, PCA
(). Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. Cell Mol Gastroenterol Hepatol.
Applications
IF, Confocal Microscopy
(). Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell.
Applications
ISH, FISH
(). TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep.
Applications
IHC, ICC, Histology
(). Regulation of the Unfolded Protein Response by BiP AMPylation protects photoreceptors from light-dependent degeneration. bioRxiv
Applications
IHC, ICC, Histology
(). Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem.
Applications
IF, Confocal Microscopy
(). A central amygdala-globus pallidus circuit conveys unconditioned stimulus information and controls fear learning. J Neurosci.
Applications
IHC, ICC, Histology
(). G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv
Applications
WB, IB, PCA
(). Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. Mol Ther.
Applications
IHC, ICC, Histology
(). Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. J Vis Exp.
Applications
IF, Confocal Microscopy
(). Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development.
Applications
IF, Confocal Microscopy
(). Characterization of a Knockin Mouse Line Expressing a Fusion Protein of Kappa Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging Via CLARITY [published online ahead of print, 2020 Jun 19]. eNeuro. 2020;ENEURO.0028-20.2020. doi:10.1523/ENEURO.0028-20.2020
Applications
IHC, ICC, Histology
(). A Human Fallopian Tube Epithelial Cell Culture Model to Study Host Responses to Chlamydia trachomatis Infection Infect Immun.
Applications
IF, Confocal Microscopy
(). Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. PLoS Genet
Applications
IF, Confocal Microscopy
(). Rapid image deconvolution and multiview fusion for optical microscopy. Nat Biotechnol.
Applications
IHC, ICC, Histology
(). Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development.
Applications
IHC, ICC, Histology
(). Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging. bioRxiv
Applications
IP, Co-IP
(). An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol.
Applications
IF, Confocal Microscopy
(). Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter J Mol Cell Cardiol.
Applications
IF, Confocal Microscopy
(). The neurokinin-1 receptor is expressed with gastrin-releasing peptide receptor in spinal interneurons and modulates itch. J Neurosci.
Applications
IHC, ICC, Histology
(). A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue. Oncotarget.
Applications
IHC, ICC, Histology
(). Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis. Dev Cell.
Applications
Undefined
(). Development of a mouse reporter strain for the purinergic P2X2 receptor. eNeuro.
Applications
IF, Confocal Microscopy
(). A cortico-collicular circuit for accurate orientation to shelter during escape. bioRxiv
Applications
IHC, ICC, Histology
(). Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun.
Applications
IF, Confocal Microscopy
(). ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol.
Applications
IHC, ICC, Histology
(). Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun.
Applications
IHC, ICC, Histology
(). CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. J Invest Dermatol.
Applications
IF, Confocal Microscopy
(). RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism. Curr Biol.
Applications
IF, Confocal Microscopy
(). Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Cell Rep
Applications
IF, Confocal Microscopy
(). Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism. Nat Commun.
Applications
IF, Confocal Microscopy
(). A lineage-tracing tool to map the fate of hypoxic tumour cells. Dis Model Mech.
Applications
IF, Confocal Microscopy
(). Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation. Sci Adv.
Applications
IF, Confocal Microscopy
(). LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Sci Adv.
Applications
IF, Confocal Microscopy
(). Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet.
Applications
IHC, ICC, Histology
(). Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep.
Applications
IF, Confocal Microscopy
(). A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues. Proc Natl Acad Sci U S A.
Applications
IF, Confocal Microscopy
(). Defining the lineage of thermogenic perivascular adipose tissue. Nat Metab.
Applications
IF, Confocal Microscopy
(). Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nat Biomed Eng.
Applications
IF, Confocal Microscopy
(). Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury. Cereb Cortex.
Applications
IHC, ICC, Histology
(). Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Dev Cell.
Applications
IF, Confocal Microscopy
(). Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death. J Cell Biol.
Applications
Undefined
(). Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun.
Applications
IHC, ICC, Histology
(). Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons Proc Natl Acad Sci U S A.
Applications
IHC, ICC, Histology
(). Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene.
Applications
IF, Confocal Microscopy
(). Development of a genetically-encoded oxytocin sensor. bioRxiv
Applications
IHC, ICC, Histology
(). AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature.
Applications
IHC, ICC, Histology
(). Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. Elife.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J.
Applications
IHC, ICC, Histology
(). CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation. Neuron.
Applications
IF, Confocal Microscopy
(). A genetic system for tissue-specific inhibition of cell proliferation. Development.
Applications
IHC, ICC, Histology
(). Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife.
Applications
ISH, FISH
(). Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons. Nat Commun.
Applications
IHC, ICC, Histology
(). Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. Elife.
Applications
IF, Confocal Microscopy
(). VE-cadherin endocytosis controls vascular integrity and patterning during development. J Cell Biol.
Applications
IF, Confocal Microscopy
(). Adipokines set neural tone by regulating synapse number. Cell Metab.
Applications
IF, Confocal Microscopy
(). Cocaine Triggers Glial-Mediated Synaptogenesis. Biol Psychiatry.
Applications
IHC, ICC, Histology
(). The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation. Cell Rep.
Applications
IF, Confocal Microscopy
(). Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design. Cell.
Applications
WB, IB, PCA
(). ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells. bioRxiv
Applications
WB, IB, PCA
(). Phox2a defines a developmental origin of the anterolateral system in mice and humans. Cell Rep
Applications
IHC, ICC, Histology
(). Excitatory and Inhibitory Subnetworks Are Equally Selective during Decision-Making and Emerge Simultaneously during Learning. Neuron.
Applications
IF, Confocal Microscopy
(). Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set. Science
Applications
IF, Confocal Microscopy
(). Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction. PLoS Biol.
Applications
IF, Confocal Microscopy
(). The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death. J Neurosci
Applications
IF, Confocal Microscopy
(). Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature.
Applications
IF, Confocal Microscopy
(). Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis. bioRxiv
Applications
IHC, ICC, Histology
(). Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife.
Applications
IF, Confocal Microscopy
(). Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol.
Applications
IHC, ICC, Histology; Multiplex Assay
(). A psychological stressor conveyed by appetite-linked neurons. Sci Adv.
Applications
IF, Confocal Microscopy
(). Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Rep.
Applications
IF, Confocal Microscopy
(). Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution. Stem Cell Reports
Applications
IHC, ICC, Histology
(). Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell.
Applications
Undefined
(). Epigenomic state transitions characterize tumor progression in mouse lung adenocarcinoma. Cancer Cell.
Applications
IHC, ICC, Histology
(). Neural stem cells direct axon guidance via their radial fiber scaffold. Neuron.
Applications
Undefined
(). Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes. Exp Cell Res.
Applications
IF, Confocal Microscopy
(). Cycling stem cells are radioresistant and regenerate the intestine. Cell Rep.
Applications
IF, Confocal Microscopy
(). Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model. BMC Biol.
Applications
IF, Confocal Microscopy
(). Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. Elife
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol.
Applications
IF, Confocal Microscopy
(). Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun.
Applications
IF, Confocal Microscopy
(). Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas. Elife
Applications
IHC, ICC, Histology
(). Cell-type-specific gene inactivation and in situ restoration via recombinase-based flipping of targeted genomic region. J Neurosci.
Applications
IF, Confocal Microscopy
(). Neuropathophysiological significance of the c. 1449T> C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome. Biochem Biophys Res Commun.
Applications
Undefined
(). Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. J Neurosci.
Applications
Undefined
(). Adipose stromal cells enhance decellularized adipose tissue remodeling through multimodal mechanisms. Tissue Eng Part A
Applications
IHC, ICC, Histology
(). Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition. Curr Biol.
Applications
IHC, ICC, Histology
(). Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-Kv4/Shal Coupled Regulatory System. Cell Rep.
Applications
IF, Confocal Microscopy
(). A network of macrophages supports mitochondrial homeostasis in the heart. Cell.
Applications
Undefined
(). A genetically defined compartmentalized striatal direct pathway for negative reinforcement. Cell.
Applications
Undefined
(). Neural Cadherin Plays Distinct Roles for Neuronal Survival and Axon Growth under Different Regenerative Conditions. eNeuro.
Applications
IHC, ICC, Histology
(). Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants. Genome Res.
Applications
WB, IB, PCA
(). EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Struct Funct.
Applications
IF, Confocal Microscopy
(). STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol.
Applications
IHC, ICC, Histology
(). Control of orienting movements and locomotion by Projection-Defined subsets of brainstem V2a neurons. Curr Biol.
Applications
IHC, ICC, Histology
(). The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor. Oncogene.
Applications
IHC, ICC, Histology
(). A versatile system to record cell-cell interactions. Elife
Applications
WB, IB, PCA
(). Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol.
Applications
IF, Confocal Microscopy
(). Molecular fingerprint and developmental regulation of the tegmental GABAergic and glutamatergic neurons derived from the anterior hindbrain. Cell Rep.
Applications
IHC, ICC, Histology
(). Mapping Cell Types and Efferent Pathways in the Ascending Relaxin-3 System of the Nucleus Incertus. eNeuro.
Applications
IF, Confocal Microscopy
(). Capillary cell-type specialization in the alveolus. Nature.
Applications
IF, Confocal Microscopy
(). Salamander‐Eci: An optical clearing protocol for the three‐dimensional exploration of regeneration. Dev Dyn.
Applications
IF, Confocal Microscopy
(). HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sci Adv.
Applications
WB, IB, PCA
(). FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. Nat Cell Biol.
Applications
Undefined
(). Naturally occurring hotspot cancer mutations in Gα13 promote oncogenic signaling. J Biol Chem.
Applications
WB, IB, PCA
(). An Aurora Kinase B–Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. Front Cell Dev Biol
Applications
IF, Confocal Microscopy
(). Topographically Distinct Projection Patterns of Early-Generated and Late-Generated Projection Neurons in the Mouse Olfactory Bulb. eNeuro.
Applications
IHC, ICC, Histology
(). Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake. Nat Commun.
Applications
IHC, ICC, Histology
(). A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. Sci Adv.
Applications
IHC, ICC, Histology
(). Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction. Cell Rep Med.
Applications
IF, Confocal Microscopy
(). Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions. Nat Commun.
Applications
IHC, ICC, Histology
(). Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep.
Applications
IHC, ICC, Histology
(). Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep.
Applications
IF, Confocal Microscopy
(). Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation. Cell Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PLoS Genet.
Applications
IF, Confocal Microscopy
(). A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice. J Neurosci.
Applications
IHC, ICC, Histology
(). Ex Vivo Recording of Axonal Transport Dynamics on Postnatal Organotypic Cortical Slices. STAR Protoc.
Applications
IF, Confocal Microscopy
(). Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol.
Applications
WB, IB, PCA