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Datasheet

RFP Antibody Pre-adsorbed

Rabbit Polyclonal

928 References
600-401-379S 600-401-379
25 µL 100 µg
WB, ELISA, IHC, IF, FC, EM, FISH, IP, Multiplex, Other
RFP, mScarlet, rRFP, tdTomato
Rabbit
$125.00 /Per Item
$279.00 /Per Item
25 µL $125.00
100 µg $279.00
Availability: Ships next business day Availability: Ships next business day
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

Fluorescent proteins such as Discosoma Red Fluorescent Protein (DsRed) from the mushroom anemone Discosoma sp. or green fluorescent protein (GFP) from Aequorea victoria jellyfish are widely used in research practice. Fusion proteins with RFP and GFP commonly serve as marker for gene expression and protein localization. As DsRed and GFP share only 19% identity, therefore, in general, anti-GFP antibodies do not recognize DsRed protein and vice versa. Structurally, Discosoma red fluorescent protein is similar to Aequorea green fluorescent protein in terms of its overall fold (a β-can) and chromophore-formation chemistry. However, Discosoma red fluorescent protein undergoes an additional step in the chromophore maturation and obligates tetrameric structure. Rockland offers many controls, monoclonal, and polyclonal antibodies for RFP.

Product Details

Anti-RFP (RABBIT) Antibody Min X Hu Ms and Rt Serum Proteins - 600-401-379
rabbit anti-RFP antibody, DsRed, rDsRed, Discosoma sp. Red Fluorescent Protein, Red fluorescent protein drFP583.
Rabbit
Polyclonal
IgG

Target Details

DsRed  - View All DsRed Products
RFP, mScarlet, rRFP, tdTomato
Recombinant Protein
The immunogen is a Red Fluorescent Protein (RFP) fusion protein corresponding to the full-length amino acid sequence (234aa) derived from the mushroom anemone Discosoma.
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Red Fluorescent Protein (Discosoma) coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Expect reactivity against RFP and its variants: mCherry, tdTomato, mBanana, mOrange, mPlum, mOrange and mStrawberry. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum and purified and partially purified Red Fluorescent Protein (Discosoma).  No reaction was observed against Human, Mouse or Rat serum proteins.

Application Details

ELISA, IF, IHC, WB
EM, FC, FISH, IP, Other, Multiplex  - View References
Polyclonal anti-RFP is designed to detect RFP and its variants. This antibody has been tested by ELISA, Western blot, IF, and IHC, and is suitable for use in EM, FC, FISH, IP, and multiplex assays based on published references. This antibody can be used to detect RFP by ELISA (sandwich or capture) for the direct binding of antigen. Optimal titers for applications should be determined by the researcher.

Formulation

Liquid (sterile filtered)
1.05mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
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Undefined
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Other
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Applications
IHC, ICC, Histology
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IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
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IF, Confocal Microscopy
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IF, Confocal Microscopy
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Applications
IHC, ICC, Histology
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ISH, FISH
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IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
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Applications
WB, IB, PCA
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Applications
IF, Confocal Microscopy
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Applications
IHC, ICC, Histology
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Undefined
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Applications
IHC, ICC, Histology
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Applications
Undefined
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Applications
WB, IB, PCA
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WB, IB, PCA
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IF, Confocal Microscopy
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Applications
Undefined
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Applications
WB, IB, PCA
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Applications
IF, Confocal Microscopy
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Applications
Undefined
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Applications
IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
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IF, Confocal Microscopy
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Undefined
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WB, IB, PCA
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IHC, ICC, Histology
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IHC, ICC, Histology
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IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
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IHC, ICC, Histology
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IF, Confocal Microscopy
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IHC, ICC, Histology
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IF, Confocal Microscopy
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Applications
WB, IB, PCA
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IHC, ICC, Histology
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Applications
IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
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IF, Confocal Microscopy
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Applications
Undefined
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Applications
Undefined
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Applications
IHC, ICC, Histology
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Applications
IHC, ICC, Histology
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IF, Confocal Microscopy
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Applications
IF, Confocal Microscopy
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Applications
IF, Confocal Microscopy
VPS13D bridges the ER to mitochondria and peroxisomes via Miro. J Cell Biol. ()
Applications
WB, IB, PCA
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Applications
IHC, ICC, Histology
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Applications
IHC, ICC, Histology
SARS-CoV-2 infection in the mouse olfactory system. Cell Discov. ()
Applications
IF, Confocal Microscopy
Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Cell Rep. ()
Applications
IHC, ICC, Histology
A genetically defined insula-brainstem circuit selectively controls motivational vigor. Cell. ()
Applications
Undefined
Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis. Cell Rep. ()
Applications
IHC, ICC, Histology
Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proc Natl Acad Sci USA ()
Applications
IHC, ICC, Histology
Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature. ()
Applications
IF, Confocal Microscopy
The Coiled‐Coil Forming Peptide (KVSALKE)5 Is a Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Adv Healthc Mater. ()
Applications
Undefined
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis. Nat Aging. ()
Applications
IF, Confocal Microscopy; TUNEL
Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities. PLoS One ()
Applications
IF, Confocal Microscopy
Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair. Cell Calcium. ()
Applications
Undefined
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury. Nat Commun. ()
Applications
IF, Confocal Microscopy
Inactivation of Hedgehog signal transduction in adult astrocytes results in region-specific blood–brain barrier defects. Proc Natl Acad Sci USA ()
Applications
IHC, ICC, Histology
Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev. ()
Applications
IHC, ICC, Histology
Covert capture and attenuation of a hippocampus-dependent fear memory. Nat Neurosci. ()
Applications
IHC, ICC, Histology
Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice. Science. ()
Applications
IHC, ICC, Histology
Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI Insight. ()
Applications
IF, Confocal Microscopy
Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron. ()
Applications
IHC, ICC, Histology
Quantification of adipocyte numbers following adipose tissue remodeling. Cell Rep. ()
Applications
IHC, ICC, Histology
Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. ()
Applications
Undefined
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes. J Cell Biol. ()
Applications
Undefined
Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma. Nat Cancer. ()
Applications
Undefined
Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. Nat Commun. ()
Applications
IF, Confocal Microscopy
Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep. ()
Applications
IF, Confocal Microscopy
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Sci Adv. ()
Applications
IHC, ICC, Histology
Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Rep. ()
Applications
IHC, ICC, Histology
Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis. Sci Adv. ()
Applications
IHC, ICC, Histology
IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Sci Adv. ()
Applications
IHC, ICC, Histology
Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory. Sci Immunol. ()
Applications
Undefined
Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production. iScience. ()
Applications
IF, Confocal Microscopy
Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol. ()
Applications
IF, Confocal Microscopy
Unique neural circuit connectivity of mouse proximal, middle, and distal colon defines regional colonic motor patterns. Cell Mol Gastroenterol Hepatol. ()
Applications
IHC, ICC, Histology
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. Dev Cell. ()
Applications
WB, IB, PCA
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. ()
Applications
IHC, ICC, Histology
Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv. ()
Applications
IF, Confocal Microscopy
Constructing an adult orofacial premotor atlas in Allen mouse CCF. Elife ()
Applications
IHC, ICC, Histology
Pancreatic β-cells communicate with vagal sensory neurons. Gastroenterology ()
Applications
Undefined
Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metab. ()
Applications
IF, Confocal Microscopy
Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. J Exp Med. ()
Applications
Undefined
ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain. Sci Adv. ()
Applications
IF, Confocal Microscopy
Transcriptional profiling of sequentially generated septal neuron fates. Elife. ()
Applications
IF, Confocal Microscopy
The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development ()
Applications
IHC, ICC, Histology; Other
Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states. Sci Rep. ()
Applications
IHC, ICC, Histology
HepaCAM controls astrocyte self-organization and coupling. Neuron. ()
Applications
IF, Confocal Microscopy
Cell of origin influences pancreatic cancer subtype. Cancer Discov. ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4. EMBO J. ()
Applications
IHC, ICC, Histology
Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. ()
Applications
IF, Confocal Microscopy
A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers. Nat Cell Biol. ()
Applications
Undefined
An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife. ()
Applications
IHC, ICC, Histology
Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. J Exp Med. ()
Applications
IF, Confocal Microscopy
Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Phychiatry. ()
Applications
IHC, ICC, Histology
Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells. iScience. ()
Applications
IF, Confocal Microscopy
Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting. Cell Rep. ()
Applications
IHC, ICC, Histology; Other
Genetically identified amygdala–striatal circuits for valence-specific behaviors. Nat Neurosci. ()
Applications
Undefined
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol. ()
Applications
IHC, ICC, Histology
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nat Biotechnol. ()
Applications
Undefined
Ronin governs the metabolic capacity of the embryonic lineage for post‐implantation development. EMBO Reports ()
Applications
IF, Confocal Microscopy
Microglia sense neuronal activity via GABA in the early postnatal hippocampus. Cell Rep. ()
Applications
IHC, ICC, Histology
Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biol Open ()
Applications
IF, Confocal Microscopy
Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Mol Metab. ()
Applications
IF, Confocal Microscopy
Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes. Mol Biol Cell. ()
Applications
IF, Confocal Microscopy
I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. Development ()
Applications
IF, Confocal Microscopy
RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. PLoS Biol. ()
Applications
IHC, ICC, Histology
Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice. Endocrinology ()
Applications
Undefined
Action potential-coupled Rho GTPase signaling drives presynaptic plasticity. Elife. ()
Applications
IHC, ICC, Histology
Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors. Elife. ()
Applications
IHC, ICC, Histology
Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. Nat Commun. ()
Applications
IHC, ICC, Histology
Tools for efficient analysis of neurons in a 3D reference atlas of whole mouse spinal cord. Cell Rep Methods. ()
Applications
IHC, ICC, Histology
Parallel processing by distinct classes of principal neurons in the olfactory cortex. Elife. ()
Applications
IHC, ICC, Histology
Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development. EMBO Rep. ()
Applications
WB, IB, PCA
Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Cell Rep. ()
Applications
IHC, ICC, Histology; Other
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention. Commun Biol. ()
Applications
IHC, ICC, Histology
Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis. Circulation. ()
Applications
IF, Confocal Microscopy
Pak1 and PP2A antagonize aPKC function to support cortical tension induced by the Crumbs-Yurt complex. Elife. ()
Applications
IF, Confocal Microscopy
Functional diversity for body actions in the mesencephalic locomotor region. Cell. ()
Applications
IHC, ICC, Histology
Derivation of airway basal stem cells from human pluripotent stem cells. Cell Stem Cell. ()
Applications
IF, Confocal Microscopy
Identifying oligodendrocyte enhancers governing Plp1 expression. Hum Mol Genet. ()
Applications
IF, Confocal Microscopy
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. Cell Rep. ()
Applications
IHC, ICC, Histology
Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron. ()
Applications
IHC, ICC, Histology
Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. ()
Applications
IHC, ICC, Histology
Fibroblast dedifferentiation as a determinant of successful regeneration. Dev Cell. ()
Applications
IF, Confocal Microscopy
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum. Nat Commun. ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli. Neurobiol Stress. ()
Applications
IHC, ICC, Histology
Mitochondrial ROS induced lysosomal dysfunction and autophagy impairment in an animal model of congenital hereditary endothelial dystrophy. Invest Ophthalmol Vis Sci. ()
Applications
IHC, ICC, Histology
TMEM16A and TMEM16B modulate pheromone-evoked action potential firing in mouse vomeronasal sensory neurons. eNeuro. ()
Applications
IHC, ICC, Histology
STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. J Neurosci ()
Applications
Undefined
TGFβ signaling activated by cancer-associated fibroblasts determines the histological signature of lung adenocarcinoma. Cancer Res. ()
Applications
IF, Confocal Microscopy
Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice. J Mol Endocrinol. ()
Applications
IHC, ICC, Histology
Live-Cell Imaging Technique to Visualize DAMPs Release During Regulated Cell Death. Methods Mol Biol. ()
Applications
Undefined
Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice. PLoS One ()
Applications
IHC, ICC, Histology
Modulation of both intrinsic and extrinsic factors additively promotes rewiring of corticospinal circuits after spinal cord injury. J Neurosci. ()
Applications
Undefined
NPY released from GABA neurons of the dentate gyrus specially reduces contextual fear without affecting cued or trace fear. Front Synaptic Neurosci. ()
Applications
IHC, ICC, Histology
Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation. Front Cell Dev Biol. ()
Applications
IHC, ICC, Histology
The impact of SST and PV interneurons on nonlinear synaptic integration in the neocortex. eNeuro. ()
Applications
IF, Confocal Microscopy
Experience-dependent inhibitory plasticity is mediated by CCK+ basket cells in the developing dentate gyrus. J Neurosci. ()
Applications
IHC, ICC, Histology
Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution. Methods Mol Biol. ()
Applications
Undefined
An Optimized Whole‐Mount Immunofluorescence Method for Shoot Apices. Curr Protoc. ()
Applications
Undefined
Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation In Vivo with CalExflox Mice. J Neurosci. ()
Applications
IHC, ICC, Histology
Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1‐transgenic mice. Glia. ()
Applications
IHC, ICC, Histology
Functional analysis of distinct populations of subthalamic nucleus neurons on Parkinson's disease and OCD-like behaviors in mice. Mol Psychiatry. ()
Applications
IHC, ICC, Histology
Level of hM4D (Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus. eNeuro. ()
Applications
IHC, ICC, Histology
Reconsidering the border between the visual and posterior parietal cortex of mice. Cereb Cortex. ()
Applications
IHC, ICC, Histology
Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell Rep. ()
Applications
IHC, ICC, Histology
Mouse models for studying hippocampal adult neural stem cell biology. Methods Mol Biol. ()
Applications
Undefined
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol. ()
Applications
IF, Confocal Microscopy
An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish. Elife. ()
Applications
IHC, ICC, Histology
An inhibitory hippocampal-thalamic pathway modulates remote memory retrieval. Nat Neurosci. ()
Applications
IHC, ICC, Histology
Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird. Nat Commun. ()
Applications
IHC, ICC, Histology; WB, IB, PCA
Early stem cell aging in the mature brain. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Photoreceptor nanotubes mediate the in vivo exchange of intracellular material. EMBO J. ()
Applications
IF, Confocal Microscopy
GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum. eNeuro ()
Applications
IF, Confocal Microscopy
Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun. ()
Applications
IF, Confocal Microscopy
Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol. ()
Applications
IHC, ICC, Histology
Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep. ()
Applications
IHC, ICC, Histology
Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter. IBRO Rep. ()
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol. ()
Applications
IHC, ICC, Histology; IF, Confocal Microscopy
The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse. Cell Rep. ()
Applications
IF, Confocal Microscopy
Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. Neural Dev. ()
Applications
IF, Confocal Microscopy
Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea. Sci Rep. ()
Applications
IF, Confocal Microscopy
Transcriptional activities of human elongation factor-1α and cytomegalovirus promoter in transgenic dogs generated by somatic cell nuclear transfer. PLoS One. ()
Applications
IHC, ICC, Histology
Indian hedgehog in craniofacial neural crest cells links to skeletal malocclusion by regulating associated cartilage formation and gene expression. FASEB J. ()
Applications
Undefined
Yolk-sac-derived macrophages progressively expand in the mouse kidney with age. Elife ()
Applications
IF, Confocal Microscopy
Somatostatin neurons of the bed nucleus of stria terminalis enhance associative fear memory consolidation in mice. J Neurosci. ()
Applications
IHC, ICC, Histology
Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes. Cell Struct Funct. ()
Applications
WB, IB, PCA
Activity-dependent dendritic elaboration requires Pten. Neurobiol Dis. ()
Applications
IHC, ICC, Histology
Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons. J Comp Neurol. ()
Applications
IF, Confocal Microscopy
Effects of nectin-3 misexpression on dendritic spine density during the postnatal development of layer 2/3 cortical neurons. Neural Dev ()
Applications
IHC, ICC, Histology
Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol. ()
Applications
IF, Confocal Microscopy
Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. Neural Dev. ()
Applications
IHC, ICC, Histology
Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell ()
Applications
IF, Confocal Microscopy
LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate. Gastroenterology ()
Applications
IHC, ICC, Histology
Neurogenic Niche Conversion Strategy Induces Migration and Functional Neuronal Differentiation of Neural Precursor Cells Following Brain Injury. Stem Cells Dev. ()
Applications
IF, Confocal Microscopy
Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors. Cell Mol Life Sci. ()
Applications
IF, Confocal Microscopy
A Feedforward Circuit Regulates Action Selection of Pre-mating Courtship Behavior in Female Drosophila. Curr Biol. ()
Applications
IHC, ICC, Histology
Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors. Neuron ()
Applications
IHC, ICC, Histology
Identification of Retinal Ganglion Cell Types and Brain Nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. J Comp Neurol. ()
Applications
IF, Confocal Microscopy; WB, IB, PCA
Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Front Mol Neurosci. ()
Applications
IHC, ICC, Histology
Development and characterization of an Otp conditional loss of function allele. Genesis ()
Applications
IF, Confocal Microscopy
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. ()
Applications
IF, Confocal Microscopy
Placental gene editing via trophectoderm-specific Tat-Cre/loxP recombination. Development ()
Applications
Undefined
Microstimulation of primate neocortex targeting striosomes induces negative decision-making. Eur J Neurosci. ()
Applications
Undefined
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. J Exp Med. ()
Applications
IF, Confocal Microscopy
Genetic ablation of SOD1G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression. bioRxiv ()
Applications
IF, Confocal Microscopy
Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. Neurogastroenterol Motil. Neurogastroenterol Motil. ()
Applications
IF, Confocal Microscopy
Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer ()
Applications
Undefined
Astrocytes shape the plastic response of adult cortical neurons to vision loss. Glia ()
Applications
IHC, ICC, Histology
Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron ()
Applications
Undefined
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus. bioRxiv ()
Applications
IHC, ICC, Histology
Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis. Cell Stem Cell. ()
Applications
IF, Confocal Microscopy
Generation of transgenic mice that conditionally express microRNA miR-145. Genesis. ()
Applications
IHC, ICC, Histology
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Brain ()
Applications
IHC, ICC, Histology
Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Curr Biol. ()
Applications
IF, Confocal Microscopy
A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus. ELife ()
Applications
IHC, ICC, Histology
Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner. Elife ()
Applications
WB, IB, PCA
Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. Cell Mol Gastroenterol Hepatol. ()
Applications
IF, Confocal Microscopy
Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell. ()
Applications
ISH, FISH
TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. ()
Applications
IHC, ICC, Histology
Regulation of the Unfolded Protein Response by BiP AMPylation protects photoreceptors from light-dependent degeneration. bioRxiv ()
Applications
IHC, ICC, Histology
Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem. ()
Applications
IF, Confocal Microscopy
A central amygdala-globus pallidus circuit conveys unconditioned stimulus information and controls fear learning. J Neurosci. ()
Applications
IHC, ICC, Histology
G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv ()
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
G-baToN: a versatile reporter system for cancer cell-stromal cell interactions. bioRxiv ()
Applications
WB, IB, PCA
Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. Mol Ther. ()
Applications
IHC, ICC, Histology
Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. J Vis Exp. ()
Applications
IF, Confocal Microscopy
Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development. ()
Applications
IF, Confocal Microscopy
Characterization of a Knockin Mouse Line Expressing a Fusion Protein of Kappa Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging Via CLARITY [published online ahead of print, 2020 Jun 19]. eNeuro. 2020;ENEURO.0028-20.2020. doi:10.1523/ENEURO.0028-20.2020 ()
Applications
IHC, ICC, Histology
A Human Fallopian Tube Epithelial Cell Culture Model to Study Host Responses to Chlamydia trachomatis Infection Infect Immun. ()
Applications
IF, Confocal Microscopy
Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. PLoS Genet ()
Applications
IF, Confocal Microscopy
Rapid image deconvolution and multiview fusion for optical microscopy. Nat Biotechnol. ()
Applications
IHC, ICC, Histology
Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development. ()
Applications
IHC, ICC, Histology
Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol. ()
Applications
IF, Confocal Microscopy
Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging. bioRxiv ()
Applications
IP, Co-IP
An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol. ()
Applications
IF, Confocal Microscopy
Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter J Mol Cell Cardiol. ()
Applications
IF, Confocal Microscopy
The neurokinin-1 receptor is expressed with gastrin-releasing peptide receptor in spinal interneurons and modulates itch. J Neurosci. ()
Applications
IHC, ICC, Histology
A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue. Oncotarget. ()
Applications
IHC, ICC, Histology
Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis. Dev Cell. ()
Applications
Undefined
Development of a mouse reporter strain for the purinergic P2X2 receptor. eNeuro. ()
Applications
IF, Confocal Microscopy
A cortico-collicular circuit for accurate orientation to shelter during escape. bioRxiv ()
Applications
IHC, ICC, Histology
Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun. ()
Applications
IF, Confocal Microscopy
ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol. ()
Applications
IHC, ICC, Histology
Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches. Nat Commun. ()
Applications
IHC, ICC, Histology
CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. J Invest Dermatol. ()
Applications
IF, Confocal Microscopy
RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism. Curr Biol. ()
Applications
IF, Confocal Microscopy
Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Cell Rep ()
Applications
IF, Confocal Microscopy
Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism. Nat Commun. ()
Applications
IF, Confocal Microscopy
A lineage-tracing tool to map the fate of hypoxic tumour cells. Dis Model Mech. ()
Applications
IF, Confocal Microscopy
Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation. Sci Adv. ()
Applications
IF, Confocal Microscopy
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Sci Adv. ()
Applications
IF, Confocal Microscopy
Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. PLoS Genet. ()
Applications
IHC, ICC, Histology
Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. ()
Applications
IF, Confocal Microscopy
A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues. Proc Natl Acad Sci U S A. ()
Applications
IF, Confocal Microscopy
Defining the lineage of thermogenic perivascular adipose tissue. Nat Metab. ()
Applications
IF, Confocal Microscopy
Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nat Biomed Eng. ()
Applications
IF, Confocal Microscopy
Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury. Cereb Cortex. ()
Applications
IHC, ICC, Histology
Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Dev Cell. ()
Applications
IF, Confocal Microscopy
Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death. J Cell Biol. ()
Applications
Undefined
Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. ()
Applications
IHC, ICC, Histology
Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons Proc Natl Acad Sci U S A. ()
Applications
IHC, ICC, Histology
Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene. ()
Applications
IF, Confocal Microscopy
Development of a genetically-encoded oxytocin sensor. bioRxiv ()
Applications
IHC, ICC, Histology
AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature. ()
Applications
IHC, ICC, Histology
Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. Elife. ()
Applications
IHC, ICC, Histology; WB, IB, PCA
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J. ()
Applications
IHC, ICC, Histology
CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation. Neuron. ()
Applications
IF, Confocal Microscopy
A genetic system for tissue-specific inhibition of cell proliferation. Development. ()
Applications
IHC, ICC, Histology
Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife. ()
Applications
ISH, FISH
Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons. Nat Commun. ()
Applications
IHC, ICC, Histology
Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. Elife. ()
Applications
IF, Confocal Microscopy
VE-cadherin endocytosis controls vascular integrity and patterning during development. J Cell Biol. ()
Applications
IF, Confocal Microscopy
Adipokines set neural tone by regulating synapse number. Cell Metab. ()
Applications
IF, Confocal Microscopy
Cocaine Triggers Glial-Mediated Synaptogenesis. Biol Psychiatry. ()
Applications
IHC, ICC, Histology
The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation. Cell Rep. ()
Applications
IF, Confocal Microscopy
Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design. Cell. ()
Applications
WB, IB, PCA
ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells. bioRxiv ()
Applications
WB, IB, PCA
Phox2a defines a developmental origin of the anterolateral system in mice and humans. Cell Rep ()
Applications
IHC, ICC, Histology
Excitatory and Inhibitory Subnetworks Are Equally Selective during Decision-Making and Emerge Simultaneously during Learning. Neuron. ()
Applications
IF, Confocal Microscopy
Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set. Science ()
Applications
IF, Confocal Microscopy
Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction. PLoS Biol. ()
Applications
IF, Confocal Microscopy
The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death. J Neurosci ()
Applications
IF, Confocal Microscopy
Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature. ()
Applications
IF, Confocal Microscopy
Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis. bioRxiv ()
Applications
IHC, ICC, Histology
Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. ()
Applications
IF, Confocal Microscopy
Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol. ()
Applications
IHC, ICC, Histology; Multiplex Assay
A psychological stressor conveyed by appetite-linked neurons. Sci Adv. ()
Applications
IF, Confocal Microscopy
Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Rep. ()
Applications
IF, Confocal Microscopy
Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution. Stem Cell Reports ()
Applications
IHC, ICC, Histology
Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell. ()
Applications
Undefined
Epigenomic state transitions characterize tumor progression in mouse lung adenocarcinoma. Cancer Cell. ()
Applications
IHC, ICC, Histology
Neural stem cells direct axon guidance via their radial fiber scaffold. Neuron. ()
Applications
Undefined
Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes. Exp Cell Res. ()
Applications
IF, Confocal Microscopy
Cycling stem cells are radioresistant and regenerate the intestine. Cell Rep. ()
Applications
IF, Confocal Microscopy
Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model. BMC Biol. ()
Applications
IF, Confocal Microscopy
Osterix-Cre marks distinct subsets of CD45-and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. Elife ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol. ()
Applications
IF, Confocal Microscopy
Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun. ()
Applications
IF, Confocal Microscopy
Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas. Elife ()
Applications
IHC, ICC, Histology
Cell-type-specific gene inactivation and in situ restoration via recombinase-based flipping of targeted genomic region. J Neurosci. ()
Applications
IF, Confocal Microscopy
Neuropathophysiological significance of the c. 1449T> C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome. Biochem Biophys Res Commun. ()
Applications
Undefined
Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. J Neurosci. ()
Applications
Undefined
Adipose stromal cells enhance decellularized adipose tissue remodeling through multimodal mechanisms. Tissue Eng Part A ()
Applications
IHC, ICC, Histology
Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition. Curr Biol. ()
Applications
IHC, ICC, Histology
Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-Kv4/Shal Coupled Regulatory System. Cell Rep. ()
Applications
IF, Confocal Microscopy
A network of macrophages supports mitochondrial homeostasis in the heart. Cell. ()
Applications
Undefined
A genetically defined compartmentalized striatal direct pathway for negative reinforcement. Cell. ()
Applications
Undefined
Neural Cadherin Plays Distinct Roles for Neuronal Survival and Axon Growth under Different Regenerative Conditions. eNeuro. ()
Applications
IHC, ICC, Histology
Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants. Genome Res. ()
Applications
WB, IB, PCA
EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Struct Funct. ()
Applications
IF, Confocal Microscopy
STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. ()
Applications
IHC, ICC, Histology
Control of orienting movements and locomotion by Projection-Defined subsets of brainstem V2a neurons. Curr Biol. ()
Applications
IHC, ICC, Histology
The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor. Oncogene. ()
Applications
IHC, ICC, Histology
A versatile system to record cell-cell interactions. Elife ()
Applications
WB, IB, PCA
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. ()
Applications
IF, Confocal Microscopy
Molecular fingerprint and developmental regulation of the tegmental GABAergic and glutamatergic neurons derived from the anterior hindbrain. Cell Rep. ()
Applications
IHC, ICC, Histology
Mapping Cell Types and Efferent Pathways in the Ascending Relaxin-3 System of the Nucleus Incertus. eNeuro. ()
Applications
IF, Confocal Microscopy
Capillary cell-type specialization in the alveolus. Nature. ()
Applications
IF, Confocal Microscopy
Salamander‐Eci: An optical clearing protocol for the three‐dimensional exploration of regeneration. Dev Dyn. ()
Applications
IF, Confocal Microscopy
HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Sci Adv. ()
Applications
WB, IB, PCA
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. Nat Cell Biol. ()
Applications
Undefined
Naturally occurring hotspot cancer mutations in Gα13 promote oncogenic signaling. J Biol Chem. ()
Applications
WB, IB, PCA
An Aurora Kinase B–Based Mouse System to Efficiently Identify and Analyze Proliferating Cardiomyocytes. Front Cell Dev Biol ()
Applications
IF, Confocal Microscopy
Topographically Distinct Projection Patterns of Early-Generated and Late-Generated Projection Neurons in the Mouse Olfactory Bulb. eNeuro. ()
Applications
IHC, ICC, Histology
Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake. Nat Commun. ()
Applications
IHC, ICC, Histology
A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. Sci Adv. ()
Applications
IHC, ICC, Histology
Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction. Cell Rep Med. ()
Applications
IF, Confocal Microscopy
Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions. Nat Commun. ()
Applications
IHC, ICC, Histology
Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep. ()
Applications
IHC, ICC, Histology
Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep. ()
Applications
IF, Confocal Microscopy
Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation. Cell Rep. ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PLoS Genet. ()
Applications
IF, Confocal Microscopy
A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice. J Neurosci. ()
Applications
IHC, ICC, Histology
Ex Vivo Recording of Axonal Transport Dynamics on Postnatal Organotypic Cortical Slices. STAR Protoc. ()
Applications
IF, Confocal Microscopy
Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol. ()
Applications
WB, IB, PCA
Formation of mRNP granules in Toxoplasma gondii during the lytic cycle. Mol Biochem Parasitol. ()
Applications
Undefined
Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation. STAR Protoc. ()
Applications
IF, Confocal Microscopy
Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells. J Bone Miner Res. ()
Applications
Undefined
Inhibitory interneurons regulate phasic activity of noradrenergic neurons in the mouse locus coeruleus and functional implications. J Physiol ()
Applications
Undefined
Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep. ()
Applications
IF, Confocal Microscopy
The nebulin family LIM and SH3 proteins regulate postsynaptic development and function. J Neurosci. ()
Applications
IF, Confocal Microscopy
Fruitless mutant male mosquitoes gain attraction to human odor. ELife ()
Applications
IF, Confocal Microscopy
Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis. Scientific Reports ()
Applications
IHC, ICC, Histology
In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development ()
Applications
IF, Confocal Microscopy
An evolutionarily acquired microRNA shapes development of mammalian cortical projections. Proceedings of the National Academy of Sciences of the United States of America ()
Applications
IHC, ICC, Histology
Modulation of sleep-courtship balance by nutritional status in Drosophila. ELife ()
Applications
IHC, ICC, Histology
Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation. Scientific Reports ()
Applications
IF, Confocal Microscopy
Retrograde Labeling Illuminates Distinct Topographical Organization of D1 and D2 Receptor-Positive Pyramidal Neurons in the Prefrontal Cortex of Mice. ENeuro ()
Applications
IHC, ICC, Histology
Innovations present in the primate interneuron repertoire. Nature ()
Applications
IHC, ICC, Histology
From 2D to 3D: Promising Advances in Imaging Lung Structure. Frontiers in Medicine ()
Applications
IF, Confocal Microscopy
The DMCdrive: practical 3D-printable micro-drive system for reliable chronic multi-tetrode recording and optogenetic application in freely behaving rodents. Scientific Reports ()
Applications
IHC, ICC, Histology
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Developmental Cell ()
Applications
IHC, ICC, Histology
IDO1+ Paneth cells promote immune escape of colorectal cancer. Communications Biology ()
Applications
IHC, ICC, Histology
An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques. Neuron ()
Applications
IHC, ICC, Histology
Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron ()
Applications
IF, Confocal Microscopy
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications ()
Applications
IF, Confocal Microscopy
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Nature ()
Applications
IF, Confocal Microscopy
Osteoclasts Derive Predominantly from Bone Marrow-Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair. Journal of Immunology (Baltimore, Md. : 1950) ()
Applications
IF, Confocal Microscopy
Multiplexed calcium imaging of single-synapse activity and astroglial responses in the intact brain. Neuroscience Letters ()
Applications
IF, Confocal Microscopy
Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition. Protein & Cell ()
Applications
IF, Confocal Microscopy
E-cadherin is Required for the Homeostasis of Lgr5+ Gastric Antral Stem Cells. International Journal of Biological Sciences ()
Applications
IHC, ICC, Histology
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nature Communications ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Scientific Reports ()
Applications
IF, Confocal Microscopy
Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina. Investigative Ophthalmology & Visual Science ()
Applications
IF, Confocal Microscopy
Developmental regulation of regenerative potential in Drosophila by ecdysone through a bistable loop of ZBTB transcription factors. PLOS Biology ()
Applications
IHC, ICC, Histology
Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells. Cell Communication and Signaling ()
Applications
WB, IB, PCA
Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model. Cell Death & Differentiation ()
Applications
IF, Confocal Microscopy
KCC2 overexpression prevents the paradoxical seizure-promoting action of somatic inhibition. Nature Communications ()
Applications
IHC, ICC, Histology
Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance. Front Endocrinol (Lausanne) ()
Applications
WB, IB, PCA
Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques. Front Neuroanat. ()
Applications
IHC, ICC, Histology
Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture. FASEB J. ()
Applications
IHC, ICC, Histology
CBP and p300 coactivators contribute to the maintenance of Isl1 expression by the Onecut transcription factors in embryonic spinal motor neurons. Mol Cell Neurosci. ()
Applications
IF, Confocal Microscopy
Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease. Anat Rec (Hoboken) ()
Applications
IHC, ICC, Histology
Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex. Neuron ()
Applications
IF, Confocal Microscopy
Medial Amygdala Kiss1 Neurons Mediate Female Pheromone Stimulation of Luteinizing Hormone in Male Mice. Neuroendocrinology ()
Applications
IHC, ICC, Histology
Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties. Cell Rep. ()
Applications
IF, Confocal Microscopy
Quantifying autophagic flux in kidney tissue using structured illumination microscopy. Methods Cell Biol. ()
Applications
IHC, ICC, Histology
Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus. J Neurosci. ()
Applications
IHC, ICC, Histology
Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol. ()
Applications
IF, Confocal Microscopy; WB, IB, PCA
Estrogen Regulates the Satellite Cell Compartment in Females. Cell Rep. ()
Applications
IF, Confocal Microscopy
Regional differences in mitral cell development in mouse olfactory bulb. J Comp Neurol. ()
Applications
IF, Confocal Microscopy
Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry. Neurobiol Dis. ()
Applications
IHC, ICC, Histology
Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res. ()
Applications
IF, Confocal Microscopy
Generation and characterization of Lhx4tdT reporter knock-in and Lhx4loxP conditional knockout mice. Genesis ()
Applications
IHC, ICC, Histology
Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Cell. ()
Applications
IHC, ICC, Histology
Genetic access to neurons in the accessory optic system reveals a role for Sema6A in midbrain circuitry mediating motion perception. J Comp Neurol. ()
Applications
IHC, ICC, Histology
Molar Bud-to-Cap Transition Is Proliferation Independent. J Dent Res. ()
Applications
IF, Confocal Microscopy
A Flower-Specific Phospholipase D Is a Stigmatic Compatibility Factor Targeted by the Self-Incompatibility Response in Brassica napus. Curr Biol. ()
Applications
WB, IB, PCA
BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell ()
Applications
IHC, ICC, Histology
Extended Flight Bouts Require Disinhibition from GABAergic Mushroom Body Neurons. Curr Biol. ()
Applications
IHC, ICC, Histology
A Non-Canonical Cortico-Amygdala Inhibitory Loop. J Neurosci. ()
Applications
IHC, ICC, Histology
Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice. PLoS One. ()
Applications
IF, Confocal Microscopy
An optimized protocol for iDISCO+ rat brain clearing, imaging, and analysis. bioRxiv ()
Applications
IHC, ICC, Histology
Hyper-diversity of CRH interneurons in mouse hippocampus. Brain Struct Funct. ()
Applications
IF, Confocal Microscopy
Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron ()
Applications
IF, Confocal Microscopy
Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. Epilepsia ()
Applications
IF, Confocal Microscopy
Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus. Curr Biol. ()
Applications
IHC, ICC, Histology
Architecture and organization of mouse posterior parietal cortex relative to extrastriate areas. Eur J Neurosci. ()
Applications
IF, Confocal Microscopy
Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells. Neuron ()
Applications
IHC, ICC, Histology
The Projection Targets of Medium Spiny Neurons Govern Cocaine-Evoked Synaptic Plasticity in the Nucleus Accumbens. Cell Rep. ()
Applications
IF, Confocal Microscopy
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature ()
Applications
IHC, ICC, Histology
Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. J Comp Neurol. ()
Applications
Array Hybridization
Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell. ()
Applications
IHC, ICC, Histology
Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. Cell Rep. ()
Applications
IHC, ICC, Histology
Lmx1b is required at multiple stages to build expansive serotonergic axon architectures. Elife. ()
Applications
IHC, ICC, Histology
Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward. Neuron. ()
Applications
IHC, ICC, Histology
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell ()
Applications
IHC, ICC, Histology
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron ()
Applications
IHC, ICC, Histology
Multiple cell types form the VIP amacrine cell population. J Comp Neurol. ()
Applications
IHC, ICC, Histology
A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion. Cell Rep. ()
Applications
IHC, ICC, Histology
Methods for renal lineage tracing: In vivo and beyond. Methods Cell Biol. ()
Applications
IF, Confocal Microscopy
Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans. Nat Neurosci. ()
Applications
IF, Confocal Microscopy
Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs. Cell Rep. ()
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology. Cell Stem Cell. ()
Applications
IF, Confocal Microscopy
Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs. Elife. ()
Applications
IHC, ICC, Histology
Sweet neurons inhibit texture discrimination by signaling TMC-expressing mechanosensitive neurons in Drosophila. Elife. ()
Applications
IF, Confocal Microscopy
Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs. Nat Neurosci. ()
Applications
IHC, ICC, Histology
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. ()
Applications
IHC, ICC, Histology
Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Cell Rep. ()
Applications
WB, IB, PCA
p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. Matrix Biol. ()
Applications
IHC, ICC, Histology
Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet. ()
Applications
Undefined
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nat Commun. ()
Applications
LCI-S, SMART, FRET
Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. ()
Applications
IHC, ICC, Histology
Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors. J Cell Sci. ()
Applications
IP, Co-IP
Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. Arthritis Res Ther. ()
Applications
IHC, ICC, Histology
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. ()
Applications
IHC, ICC, Histology
Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation. J Comp Neurol. ()
Applications
IF, Confocal Microscopy
Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration. Stem Cell Reports. ()
Applications
IF, Confocal Microscopy
In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. ()
Applications
IF, Confocal Microscopy
Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma. Nat Commun. ()
Applications
IF, Confocal Microscopy
GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. ()
Applications
IF, Confocal Microscopy
Reporter lines based on the gexp02 promoter enable early quantification of sexual conversion rates in the malaria parasite Plasmodium falciparum. Sci Rep. ()
Applications
IF, Confocal Microscopy
Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. ()
Applications
IHC, ICC, Histology
Innovations in Primate Interneuron Repertoire. Nature ()
Applications
IHC, ICC, Histology
Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor. Cell Rep. ()
Applications
IF, Confocal Microscopy
Temporal evolution of cortical ensembles promoting remote memory retrieval. Nat Neurosci. ()
Applications
iDISCO
Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development. ()
Applications
IHC, ICC, Histology
Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep. ()
Applications
IF, Confocal Microscopy
Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors. Elife. ()
Applications
IHC, ICC, Histology
Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron ()
Applications
WB, IB, PCA
Transmission Electron Microscopy of Oligodendrocytes and Myelin. Methods Mol Biol. ()
Applications
Immuno-EM
A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling. Cell Stem Cell. ()
Applications
IF, Confocal Microscopy
Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells. Cell Rep. ()
Applications
IF, Confocal Microscopy
Precise Long-Range Microcircuit-to-Microcircuit Communication Connects the Frontal and Sensory Cortices in the Mammalian Brain. Neuron. ()
Applications
IHC, ICC, Histology
TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex. Nat Commun. ()
Applications
IHC, ICC, Histology
Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases. J Mol Biol. ()
Applications
WB, IB, PCA
Exocyst dynamics during vesicle tethering and fusion. Nat Commun. ()
Applications
WB, IB, PCA
Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits. Neuron. ()
Applications
IF, Confocal Microscopy
Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Rep. ()
Applications
IHC, ICC, Histology
Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues. Dev Cell. ()
Applications
IHC, ICC, Histology
A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nat Cell Biol. ()
Applications
IF, Confocal Microscopy
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol. ()
Applications
IF, Confocal Microscopy
Muscle-selective RUNX3 dependence of sensorimotor circuit development. Development. ()
Applications
IF, Confocal Microscopy
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium. Nat Commun. ()
Applications
IHC, ICC, Histology
Interleukin-17 Regulates Neuron-Glial Communications, Synaptic Transmission, and Neuropathic Pain after Chemotherapy. Cell Rep. ()
Applications
IF, Confocal Microscopy
Regulation of Energy Expenditure by Brainstem GABA Neurons. Cell. ()
Applications
iDISCO; IF, Confocal Microscopy
Microbiota imprint gut–intrinsic neuronal programming and sympathetic activity. Nature ()
Applications
IF, Confocal Microscopy
Imaging and Manipulating Pituitary Function in the Awake Mouse. Endocrinology. ()
Applications
IF, Confocal Microscopy
Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events. Cell Rep. ()
Applications
IHC, ICC, Histology
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. Dev Cell. ()
Applications
IHC, ICC, Histology
RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach. PLoS Biol. ()
Applications
IF, Confocal Microscopy
Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach. Nat Commun. ()
Applications
IHC, ICC, Histology
Rapidly cycling stem cells regenerate the intestine independent of Lgr5high cells. bioRxiv ()
Applications
IF, Confocal Microscopy
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development. ()
Applications
IF, Confocal Microscopy
The mechanosensitive Piezo1 orchestrating angiogenesis is essential in bone fracture repair. bioRxiv ()
Applications
IF, Confocal Microscopy
Constricted migration modulates stem cell differentiation. Mol Biol Cell. ()
Applications
IF, Confocal Microscopy
Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors. JCI Insight. ()
Applications
IF, Confocal Microscopy
Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum). Nat Protoc. ()
Applications
IF, Confocal Microscopy
ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. J Cell Sci. ()
Applications
IF, Confocal Microscopy
Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells. Cancer Discov. ()
Applications
Immuno-EM
Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. ()
Applications
IF, Confocal Microscopy
Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming. Cell Rep. ()
Applications
IF, Confocal Microscopy
Presynaptic inhibition of cutaneous afferents prevents chronic itch. Cell Rep. ()
Applications
IHC, ICC, Histology
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development. Nat Commun. ()
Applications
IF, Confocal Microscopy
A chromosome folding intermediate at the condensin-to-cohesin transition during telophase. Nat Cell Biol. ()
Applications
WB, IB, PCA
The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits. J Neurosci. ()
Applications
IHC, ICC, Histology
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nat Commun. ()
Applications
IF, Confocal Microscopy
Anatomical development of the cerebellothalamic tract in embryonic mice. bioRxiv ()
Applications
IF, Confocal Microscopy
Repeated hypoglycemia blunts the responsiveness of glucose-inhibited GHRH neurons by remodeling neural inputs and disrupting mitochondrial structure and function. JCI Insight. ()
Applications
IHC, ICC, Histology
Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. Neuron. ()
Applications
IHC, ICC, Histology
A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nat Neurosci. ()
Applications
IF, Confocal Microscopy
Accelerating iterative deconvolution and multiview fusion by orders of magnitude. bioRxiv ()
Applications
IHC, ICC, Histology
Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells. Dev Cell. ()
Applications
IHC, ICC, Histology
Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart. Nat Commun. ()
Applications
IHC, ICC, Histology
Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition. Elife. ()
Applications
IF, Confocal Microscopy
Spinal V3 Interneurons and Left-Right Coordination in Mammalian Locomotion. Front Cell Neurosci. ()
Applications
IHC, ICC, Histology
Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Cell Stem Cell. ()
Applications
IF, Confocal Microscopy
Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections. Methods Mol Biol. ()
Applications
WB, IB, PCA
Somatostatin-Expressing Interneurons Enable and Maintain Learning-Dependent Sequential Activation of Pyramidal Neurons. Neuron. ()
Applications
IF, Confocal Microscopy
Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. ()
Applications
IF, Confocal Microscopy
Choice suppression through opponent but not independent function of the striatal indirect pathway. bioRxiv ()
Applications
IHC, ICC, Histology
Cell-Type-Specific D1 Dopamine Receptor Modulation of Projection Neurons and Interneurons in the Prefrontal Cortex. Cereb Cortex. ()
Applications
IF, Confocal Microscopy
Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. Cell. ()
Applications
IF, Confocal Microscopy
microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction. Cerebral Cortex ()
Applications
IHC, ICC, Histology
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nat Commun. ()
Applications
WB, IB, PCA
The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. ()
Applications
IF, Confocal Microscopy
Selection of an Efficient AAV Vector for Robust CNS Transgene Expression. Molecular Therapy. Methods & Clinical Development ()
Applications
IHC, ICC, Histology
Yorkie and JNK revert syncytial muscles into myoblasts during Org-1-dependent lineage reprogramming. The Journal of Cell Biology ()
Applications
IF, Confocal Microscopy
PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell ()
Applications
IF, Confocal Microscopy
Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene ()
Applications
IF, Confocal Microscopy
Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization. Current Biology : Cb ()
Applications
IHC, ICC, Histology
Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell ()
Applications
IF, Confocal Microscopy
Sensory noise increases metacognitive efficiency. Journal of Experimental Psychology. General ()
Applications
Undefined
Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. Experimental Neurology ()
Applications
IHC, ICC, Histology
In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ. Molecular Therapy ()
Applications
IHC, ICC, Histology
Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors. Cancer Cell ()
Applications
FC, FACS, FLOW; IF, Confocal Microscopy; IHC, ICC, Histology; qRT-PCR, RT-PCR
Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition. Neuron ()
Applications
IF, Confocal Microscopy
Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner. Nature Communications ()
Applications
IHC, ICC, Histology
Two distinct mechanisms silence chinmo in Drosophila neuroblasts and neuroepithelial cells to limit their self-renewal. Development ()
Applications
IHC, ICC, Histology
A Naturally Fluorescent Mgp Transgenic Mouse for Angiogenesis and Glaucoma Longitudinal Studies. Investigative Ophthalmology & Visual Science ()
Applications
IHC, ICC, Histology
Genetic targeting of Purkinje fibres by Sema3a-CreERT2. Scientific Reports ()
Applications
IF, Confocal Microscopy; Multiplex Assay
Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. The Journal of Neuroscience ()
Applications
WB, IB, PCA
An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus. Stem Cell Reports ()
Applications
IHC, ICC, Histology
Electrophysiological and Morphological Characterization of Chrna2 Cells in the Subiculum and CA1 of the Hippocampus: An Optogenetic Investigation. Frontiers in Cellular Neuroscience ()
Applications
IHC, ICC, Histology
Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells. Nucleic Acids Research ()
Applications
IP, Co-IP; WB, IB, PCA
Intensify3D: Normalizing signal intensity in large heterogenic image stacks. Scientific Reports ()
Applications
iDISCO
The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors. Elife ()
Applications
IP, Co-IP
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells. Nature Communications ()
Applications
IHC, ICC, Histology; ISH, FISH
Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nature Neuroscience ()
Applications
IF, Confocal Microscopy
Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nature Communications ()
Applications
IF, Confocal Microscopy
Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. Cell Reports ()
Applications
IHC, ICC, Histology
Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging Cell ()
Applications
IHC, ICC, Histology
Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development ()
Applications
IHC, ICC, Histology
LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. Nature Communications ()
Applications
WB, IB, PCA
A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits. Scientific Reports ()
Applications
IHC, ICC, Histology
Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. Cell ()
Applications
IF, Confocal Microscopy
Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. Aging ()
Applications
IF, Confocal Microscopy
Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. Cellular and Molecular Gastroenterology and Hepatology ()
Applications
IHC, ICC, Histology
Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice. PLOS Biology ()
Applications
IHC, ICC, Histology; TUNEL
Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration. Elife ()
Applications
IHC, ICC, Histology
Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics ()
Applications
WB, IB, PCA
Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC. Fluids and Barriers of the CNS ()
Applications
IF, Confocal Microscopy
Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake. Cell Metabolism ()
Applications
IHC, ICC, Histology; ISH, FISH
Intersectional Strategies for Targeting Amacrine and Ganglion Cell Types in the Mouse Retina. Frontiers in Neural Circuits ()
Applications
IHC, ICC, Histology
Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. Scientific Reports ()
Applications
IHC, ICC, Histology
Communication from Learned to Innate Olfactory Processing Centers Is Required for Memory Retrieval in Drosophila. Neuron ()
Applications
IF, Confocal Microscopy
Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyte heterogeneity. PLOS Biology ()
Applications
IHC, ICC, Histology
miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells ()
Applications
IF, Confocal Microscopy
Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations. Communications Biology ()
Applications
IHC, ICC, Histology
In utero CRISPR-mediated therapeutic editing of metabolic genes. Nature Medicine ()
Applications
IF, Confocal Microscopy
Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication. Cell Reports ()
Applications
IF, Confocal Microscopy
A complex peripheral code for salt taste in Drosophila. Elife ()
Applications
IHC, ICC, Histology; Multiplex Assay
Probing aggrephagy using chemically-induced protein aggregates. Nature Communications ()
Applications
IP, Co-IP
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs. Nature Communications ()
Applications
LCI-S, SMART, FRET
Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses. Journal of Clinical Investigation ()
Applications
IF, Confocal Microscopy
Exocyst dynamics during vesicle tethering and fusion. Nature Communications ()
Applications
WB, IB, PCA
Profiling proliferative cells and their progeny in damaged murine hearts. Proc. Natl. Acad. Sci. U.S.A ()
Applications
IF, Confocal Microscopy
Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1. Cell Reports ()
Applications
IF, Confocal Microscopy
OCRL Deficiency Impairs Endolysosomal Function in a Humanized Mouse Model for Lowe Syndrome and Dent Disease. Human Molecular Genetics ()
Applications
IF, Confocal Microscopy
Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. Journal of Clinical Investigation ()
Applications
IHC, ICC, Histology
The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion. Molecular Biology of the Cell ()
Applications
WB, IB, PCA
Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex. Frontiers in Cellular Neuroscience ()
Applications
IF, Confocal Microscopy; Multiplex Assay
Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues. Molecular Metabolism ()
Applications
IF, Confocal Microscopy
The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human Mutation ()
Applications
WB, IB, PCA
Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2. Frontiers in Cellular Neuroscience ()
Applications
IHC, ICC, Histology
Optical Approaches for Interrogating Neural Circuits Controlling Hormone Secretion. Endocrinology ()
Applications
IHC, ICC, Histology
Thalamostriatal and cerebellothalamic pathways in a songbird, the Bengalese finch. J Comp Neurol. ()
Applications
IF, Confocal Microscopy
Genetic lineage tracing analysis of c-kit+ stem/progenitor cells revealed a contribution to vascular injury-induced neointimal lesions. J Mol Cell Cardiol. ()
Applications
IF, Confocal Microscopy
Limited Regeneration of Adult Salivary Glands after Severe Injury Involves Cellular Plasticity. Cell Rep. ()
Applications
IHC, ICC, Histology
Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction. Biochem Biophys Res Commun. ()
Applications
IHC, ICC, Histology
Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains. Brain Struct Funct. ()
Applications
IHC, ICC, Histology
Reconstruction of the Human Colon Epithelium In Vivo. Cell Stem Cell ()
Applications
IF, Confocal Microscopy
Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis. Cell Rep. ()
Applications
IF, Confocal Microscopy
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. ()
Applications
WB, IB, PCA; IF, Confocal Microscopy
A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development ()
Applications
WB, IB, PCA; IF, Confocal Microscopy
Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cereb Cortex. ()
Applications
IHC, ICC, Histology
KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity. Immunity ()
Applications
FC, FACS, FLOW
Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell. ()
Applications
IHC, ICC, Histology
ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea. Eur J Neurosci. ()
Applications
IF, Confocal Microscopy
Genetic dissection of the neuro-glio-vascular machinery in the adult brain. Mol Brain. ()
Applications
IHC, ICC, Histology
Genetic Targeting of Organ-Specific Blood Vessels. Circ Res. ()
Applications
IF, Confocal Microscopy
A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices. Cell Rep. ()
Applications
IHC, ICC, Histology
Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells. FASEB J. ()
Applications
IHC, ICC, Histology
Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication. Curr Biol. ()
Applications
IF, Confocal Microscopy
The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron ()
Applications
IF, Confocal Microscopy
Parallel Arousal Pathways in the Lateral Hypothalamus. eNeuro ()
Applications
IHC, ICC, Histology
Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Curr Biol. ()
Applications
IF, Confocal Microscopy
An Optical Neuron-Astrocyte Proximity Assay at Synaptic Distance Scales. Neuron ()
Applications
IHC, ICC, Histology
Neuronal connections of the central amygdalar nucleus with refeeding-activated brain areas in rats. Brain Struct Funct. ()
Applications
IF, Confocal Microscopy
A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons. Neuron ()
Applications
IF, Confocal Microscopy
A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period. Neuron ()
Applications
IF, Confocal Microscopy
Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors. Cell Rep. ()
Applications
WB, IB, PCA
Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior. Neuron ()
Applications
IHC, ICC, Histology
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metab. ()
Applications
IHC, ICC, Histology
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression. Nature. ()
Applications
IHC, ICC, Histology
A synaptic threshold mechanism for computing escape decisions. Nature ()
Applications
IHC, ICC, Histology
Genetic lineage tracing of resident stem cells by DeaLT. Nat Protoc. ()
Applications
IF, Confocal Microscopy
Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. ()
Applications
IF, Confocal Microscopy
Visual Projection Neurons Mediating Directed Courtship in Drosophila. Cell. ()
Applications
IF, Confocal Microscopy
Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell. ()
Applications
WB, IB, PCA; IF, Confocal Microscopy