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Product Categories
Host Species
Conjugation
Clonality
Format
Sample Size

ModDetect® Phosphorothioate Clone PS05

Mouse Monoclonal PS05 IgG2a

3 References

Size: 100 µg

Applications: ELISA, IF, Multiplex

200-301-MV1
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ModDetect® Phosphorothioate Clone PS03

Mouse Monoclonal PS03 IgG2a

3 References

Size: 25 µL, 100 µg

Applications: ELISA, IHC, IF, Multiplex

200-301-MU9
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Biotinylated Panel

3 References

Size: 1 Set

KNA-201
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Panel

3 References

Size: 1 Set

Applications: ELISA, IF, Multiplex

KNA-200
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ModDetect® Phosphorothioate Panel

3 References

Size: 1 Set

Applications: ELISA, IF, Multiplex

KNA-100
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ModDetect® Phosphorothioate Biotin Panel

3 References

Size: 1 Set

Applications: ELISA

KNA-101
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Clone MOE1

Mouse Monoclonal MOE1 IgG1

2 References

Size: 100 µg

Applications: ELISA, IF, Multiplex

200-301-NF0
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Clone MOE3

Mouse Monoclonal MOE3 IgG1

2 References

Size: 100 µg

Applications: ELISA, IF, Multiplex

200-301-NF1
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Clone MOE4

Mouse Monoclonal MOE4 IgG1

2 References

Size: 100 µg

Applications: ELISA, IF, Multiplex

200-301-NF2
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ModDetect® 2'-O-Methoxyethyl (2'MOE) Clone MOE9

Mouse Monoclonal MOE9 IgG1

2 References

Size: 100 µg

Applications: ELISA, IF, Multiplex

200-301-NF3
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Resource Type

Bioanalytical Assays for Oligonucleotide Therapeutics

Literature
This peer-reviewed manuscript explores anti-PS monoclonal antibodies as universal detection reagents for ONT analysis via IF, ELISA, IHC, and IP.
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Characterising antibodies targeting antisense oligonucleotide (ASO) modifications for quantification of intracellular trafficking

Scientific Posters
This poster, created with NATA, demonstrates LNA and 2'MOE ASOs detection using ModDetect® anti-PS antibodies. It explores endosomal accumulation post-delivery and in vivo mouse liver detection.
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Localization and Quantification of Oligonucleotide Therapeutic Drugs

Scientific Posters
This poster presents the development of universal detection reagents specific for nucleic acid modifications.
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Methods for Analysis of Oligonucleotide Drugs

Literature
Explore the critical role of sensitive analytical assays in advancing antisense oligonucleotide (ASO) drug development.
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Methods for Analysis of siRNA

Literature
Learn how ModDetect reagents were validated with FDA-approved drug Lumairan, providing reliable quantification for small interfering (siRNA)
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New Tools to Quantify and Localize ASOs and siRNAs

White Papers
Discover ModDetect™: advanced tools for precise quantification and localization of modified oligonucleotides, enhancing RNA-based therapeutic research.
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Nucleic Acid Modifications in Drug Development

Articles
The use of nucleic acid-based drugs has long been understood as having great promise because of its compelling logic.
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Tau Antibodies

Articles
Alzheimer's disease (AD) is characterized by the presence of β-amyloid peptide and phosphorylated tau protein.
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