Datasheet

VDAC1 Antibody Streptavidin

Name: VDAC1 Antibody Streptavidin
Brand: Rockland Immunochemicals
Availability: OutOfStock

Mouse Monoclonal S152B-23 IgG2a

Item No. 200-366-W70

Size: 100 µg

Reactivity: H. sapiens (Human), Mus musculus (Mouse), Rattus (Rat)

Host Species: Mouse

This product is discontinued

Background

Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis. Anti-VDAC1 is ideal for research in Cell Biology and Apoptosis.

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Specifications for VDAC1 Antibody Streptavidin

Product Details

Description: Anti-VDAC1 (MOUSE) Monoclonal Antibody Streptavidin Conjugated - 200-366-W70

Synonyms: Voltage Dependent Anion Channel 1, Porin, Voltage dependent anion selective channel protein 1, Voltage-dependent anion-selective channel protein 1, hVDAC1, MGC111064, Mitochondrial Porin, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin

Host Species: Mouse

Conjugate: Streptavidin

Clonality: Monoclonal

Format: IgG2a

Target Details

Gene Name: VDAC1 - View All VDAC1 Products

Reactivity: H. sapiens (Human), Mus musculus (Mouse), Rattus (Rat)

Immunogen Type: Recombinant Protein

Immunogen: Anti-VDAC1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-293 (full length) of human VDAC1.

Purity/Specificity: Anti-VDAC1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 98% identical to mouse, 98% identical to rat and >60% identical to VDAC2 and VDAC3.

Database Links:

UniProtKB - P21796

GeneID - 7416

NCBI - NP_003365

Application Details

Application Note: Anti-VDAC1 Streptavidin Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~30kDa on specific lysates or tissues. Does not cross react with VDAC2 or VDAC3 (based on KO validation results). Specific conditions for reactivity should be optimized by the end user.

Formulation

Physical State: Liquid (sterile filtered)

Concentration: 1mg/mL by UV absorbance at 280 nm

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: 0.1% (w/v) Sodium Azide

Stabilizer: 50% (v/v) Glycerol

Shipping & Handling

Shipping Condition: Wet Ice

Storage Condition: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiration: Expiration date is one (1) year from date of receipt.

Certificate of Analysis Lookup

Disclaimer

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.