TSLP Antibody
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Datasheet

TSLP Antibody

Rabbit Polyclonal

600-401-H30
100 µg
ELISA, IF, IHC, WB
Human, Mouse
Rabbit
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$411.00 /Per Item
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Description

Background

TSLP antibody detects human TSLP. Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. At least two differentially spliced isoforms of TSLP are known to exist. Anti-TSLP antibodies are ideal for investigators involved in neuroscience research.

Application Note

Anti-TSLP Antibody is tested for use in E, WB, IF, and IHC. Expect a band approximately ~18.1 kDa on specific lysates. Western Blot, Immunohistochemistry, and Immunofluorescence tested in human and mouse samples; Immunocytochemistry in human samples. Specific conditions for reactivity should be optimized by the end user.

Purity/Specificity

Anti-TSLP Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with TSLP with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with TSLP from other sources has not been determined.

Anti-TSLP (RABBIT) Antibody - 600-401-H30
Thymic stromal lymphopoietin
TSLP
ELISA, IF, IHC, WB
Human, Mouse
Rabbit
Polyclonal
IgG
Peptide
TSLP Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to an internal region of human TSLP.
Liquid (sterile filtered)
1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.02% (w/v) Sodium Azide
None
Wet Ice
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Expiration date is one (1) year from date of opening.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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