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            NOSTRIN Antibody
Rabbit Polyclonal
            
                600-401-DD6
        
        
            
                100 µg
        
            
                
                    Liquid (sterile filtered)
            
            
                
                WB, ELISA, IHC, IF
            
                    
                
                Human, Mouse, Rat
            
                            
                
                 Rabbit
            
                
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Anti-NOSTRIN (RABBIT) Antibody - 600-401-DD6                    
                
                
                    
                    
Nitric oxide synthase traffic inducer, eNOS-trafficking inducer, Nitric oxide synthase trafficker, BM247 homolog, DaIP2                    
                
                
                    
                    
Rabbit                    
                
                
                    
                    
Polyclonal                    
                
                
                    
                    
IgG                    
                
            Target Details
                    
                    
NOSTRIN                         - View All NOSTRIN Products
                            
                    
                
                
                    
                    
Human, Mouse, Rat                                            
                
                
                    
                    
Conjugated Peptide                                            
                
                
                    
                    
Anti-NOSTRIN antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human NOSTRIN.                                            
                
                
                    
                    
Anti-NOSTRIN antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. NOSTRIN antibody is human, mouse and rat reactive.  At least four isoforms are known to exist; this antibody will detect all four isoforms.                                            
                
                
                Application Details
                        
                        
ELISA, IF, IHC, WB
                        
                    
                    
                        
                        
Anti-NOSTRIN Antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 58 kDa in Western Blots of specific cell lysates and tissues.
                        
                    
                                                    Formulation
                        
                        
1 mg/mL by UV absorbance at 280 nm                        
                    
                    
                        
                        
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2                        
                    
                    
                        
                        
0.02% (w/v) Sodium Azide                        
                    
                    
                        
                        
None                        
                    
            Shipping & Handling
                    
                    
Dry Ice                    
                
                
                    
                    
Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.                    
                
                
                    
                    
Expiration date is one (1) year from date of receipt.                    
                
        
                NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localization and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).
            
        
            This product is for research use only and is not intended for therapeutic or diagnostic applications.  Please contact a technical service representative for more information.  All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin.  Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.  All properties listed are typical characteristics and are not specifications.  All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control.  All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale.  Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc.  If you require a commercial license to use this material and do not have one, then return this material, unopened to:  Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.