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Datasheet SDS

GFP Antibody

Goat Polyclonal

419 References
600-101-215S 600-101-215M 600-101-215
25 µL 100 µg 1 mg
Liquid (sterile filtered) Liquid (sterile filtered) Liquid (sterile filtered)
WB, ELISA, IHC, IF, FC, EM, FISH, IP, Multiplex, Other, Purification
GFP, eGFP, rGFP
Goat
$125.00 /Per Item
$399.00 /Per Item
$619.00 /Per Item
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

Green fluorescent protein is a 27 kDa protein produced from the jellyfish Aequorea victoria, which emits green light (emission peak at a wavelength of 509nm) when excited by blue light. GFP is an important tool in cell biology research. GFP is widely used enabling researchers to visualize and localize GFP-tagged proteins within living cells without the need for chemical staining.

Product Details

Anti-GFP (GOAT) Antibody - 600-101-215
goat anti-GFP Antibody, GFP, Green Fluorescent Protein, GFP antibody, Green Fluorescent Protein antibody, EGFP, enhanced Green Fluorescent Protein, Aequorea victoria, Jellyfish
Goat
Polyclonal
IgG

Target Details

GFP, eGFP, rGFP
Recombinant Protein
The immunogen is a Green Fluorescent Protein (GFP) fusion protein corresponding to the full length amino acid sequence (246aa) derived from the jellyfish Aequorea victoria.
GFP antibody was prepared from monospecific antiserum by immunoaffinity chromatography using Green Fluorescent Protein (Aequorea victoria) coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum and purified and partially purified Green Fluorescent Protein (Aequorea victoria). No reaction was observed against Human, Mouse or Rat serum proteins.

Application Details

ELISA, IF, WB
EM, FC, FISH, IHC, IP, Other, Purification, Multiplex  - View References
Anti-GFP is designed to detect GFP and its variants. Goat Anti-GFP has been tested by ELISA, Western blot, and immunofluorescence. This product is also suitable for EM, FC, FISH, IHC, IP, purification, and multiplex assays based on published references. This antibody can be used to detect GFP by ELISA (sandwich or capture) for the direct binding of antigen and recognizes wild-type, recombinant, and enhanced forms of GFP. Researchers should determine optimal titers for applications.

Formulation

1.18 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store GFP antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
(). Phosphorylation of Bub1 by Mph1 promotes Bub1 signaling at the kinetochore to ensure accurate chromosome segregation. J Biol Chem.
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(). Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Dev Cell.
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(). Serotonergic neurons control cortical neuronal intracellular energy dynamics by modulating astrocyte-neuron lactate shuttle. iScience.
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(). Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cell Mol Life Sci.
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(). Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK. Cells.
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IF, Confocal Microscopy
(). Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born juxtaglomerular neurons in the mouse olfactory bulb. Cell Mol Life Sci.
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IHC, ICC, Histology
(). Behavioral context improves optogenetic stimulation of transplanted dopaminergic cells in unilateral 6-OHDA rats. Behav Brain Res.
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IHC, ICC, Histology
(). FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells. PLoS Biol.
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(). Exocrine gland-resident memory CD8+ T cells use mechanosensing for tissue surveillance. Sci Immunol.
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IF, Confocal Microscopy
(). CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. Nat Commun.
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IF, Confocal Microscopy
(). Netrins and Netrin Receptors are Essential for Normal Targeting of Sensory Axons in the Zebrafish Olfactory Bulb. Neuroscience.
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IHC, ICC, Histology
(). The fission yeast kinetochore complex Mhf1-Mhf2 regulates the spindle assembly checkpoint and faithful chromosome segregation. J Cell Sci.
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WB, IB, PCA
(). Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II-dependent fashion. J Cell Biol.
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WB, IB, PCA
(). Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X syndrome. Proc Natl Acad Sci U S A.
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IF, Confocal Microscopy
(). Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis. STAR Protoc.
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IF, Confocal Microscopy
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IHC, ICC, Histology
(). Morphogenesis of Bullet-Shaped Rabies Virus Particles Regulated by TSG101. J Virol.
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(). The proprotein convertase BLI-4 promotes collagen secretion prior to assembly of the Caenorhabditis elegans cuticle. PLoS Genet.
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WB, IB, PCA
(). The β Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5β, Localizes to the Endoplasmic Reticulum. Int J Mol Sci.
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WB, IB, PCA
(). Transient receptor potential Ankyrin-1 (TRPA1) agonists suppress myelination and induce demyelination in organotypic cortical slices. Glia.
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WB, IB, PCA
(). CXCR4 and CXCL12 signaling regulates the development of extrinsic innervation to the colorectum Development.
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IF, Confocal Microscopy
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IHC, ICC, Histology
(). The Cdc42 GTPase activating protein Rga6 promotes the cortical localization of Septin. J Cell Sci.
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WB, IB, PCA
(). PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP‐HSP70‐BAG3 complex and the aggregation of ubiquitinated proteins. FASEB J.
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WB, IB, PCA
(). Loss of Neuropilin2a/b or Sema3fa alters olfactory sensory axon dynamics and protoglomerular targeting. Neural Development
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IHC, ICC, Histology
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IF, Confocal Microscopy
(). The subthalamic corticotropin-releasing hormone neurons mediate adaptive REM-sleep responses to threat. Neuron.
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Undefined
(). The ESCRT machinery directs quality control over inner nuclear membrane architecture. Cell Rep.
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IF, Confocal Microscopy; WB, IB, PCA
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IF, Confocal Microscopy
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Undefined
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Undefined
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Applications
ChIP
(). Ketogenic diet uncovers differential metabolic plasticity of brain cells. Sci Adv.
Applications
IF, Confocal Microscopy
(). Overexpression of Brain- and Glial Cell Line-Derived Neurotrophic Factors Is Neuroprotective in an Animal Model of Acute Hypobaric Hypoxia. Int J Mol Sci.
Applications
IHC, ICC, Histology
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Applications
IF, Confocal Microscopy
(). SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice bioRxiv Preprint
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Pim1 maintains telomere length in mouse cardiomyocytes by inhibiting TGFβ signalling. Cardiovasc Res.
Applications
IHC, ICC, Histology
(). Phosphorylation by Aurora B kinase regulates caspase-2 activity and function. Cell Death Differ.
Applications
IF, Confocal Microscopy
(). BMP10 signaling promotes the development of endocardial cells from human pluripotent stem cell-derived cardiovascular progenitors. Cell Stem Cell.
Applications
IHC, ICC, Histology
(). Nitric oxide‐mediated signal transmission in bladder vasculature as a therapeutic target of PDE5 inhibitors: Rodent model studies. Br J Parmacol.
Applications
Undefined
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Applications
IF, Confocal Microscopy
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Applications
Undefined
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Undefined
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Applications
IF, Confocal Microscopy
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Applications
IF, Confocal Microscopy
(). Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity. Cell Stem Cell.
Applications
Undefined
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Applications
IHC, ICC, Histology
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Applications
WB, IB, PCA; IF, Confocal Microscopy
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Applications
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Applications
IF, Confocal Microscopy
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Applications
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WB, IB, PCA
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Undefined
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IF, Confocal Microscopy
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IF, Confocal Microscopy
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IF, Confocal Microscopy
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IF, Confocal Microscopy
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Applications
Undefined
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Applications
IHC, ICC, Histology
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IHC, ICC, Histology
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Applications
IHC, ICC, Histology
(). Ultrasensitive tau biosensor cells detect no seeding in Alzheimer's disease CSF. Acta Neuropathol Commun.
Applications
WB, IB, PCA
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Applications
Undefined
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Applications
IHC, ICC, Histology
(). Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior. Cell Rep.
Applications
Undefined
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IHC, ICC, Histology
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Applications
IHC, ICC, Histology
(). PTBP1/HNRNP I controls intestinal epithelial cell regeneration by maintaining stem cell survival and stemness. bioRxiv Preprint
Applications
IF, Confocal Microscopy
(). Top-down acetylcholine signaling via olfactory bulb vasopressin cells contributes to social discrimination in rats. Commun Biol.
Applications
IF, Confocal Microscopy
(). Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Cell.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Upregulation of FGF9 in lung adenocarcinoma transdifferentiation to small cell lung cancer. Cancer Res.
Applications
Undefined
(). Photoreceptor nanotubes mediate the in vivo exchange of intracellular material. EMBO J.
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IF, Confocal Microscopy
(). Microglia modulate stable wakefulness via the thalamic reticular nucleus in mice. Nat Commun.
Applications
IHC, ICC, Histology
(). Visualization of individual cell division history in complex tissues using iCOUNT. Cell Stem Cell.
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IF, Confocal Microscopy
(). NaNuTrap: a technique for in vivo cell nucleus labelling using nanobodies. Development.
Applications
IF, Confocal Microscopy
(). Patterned endogenous activity controls migration, morphogenesis and survival of adult-born neurons in the mouse olfactory bulb. bioRxiv Preprint
Applications
IHC, ICC, Histology
(). TGIF1 is required for chicken ovarian cortical development and generation of the juxtacortical medulla. Development.
Applications
IF, Confocal Microscopy
(). Wiring logic of the early rodent olfactory system revealed by high-throughput sequencing of single neuron projections. bioRxiv Preprint
Applications
IHC, ICC, Histology
(). Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation. J Neurosci.
Applications
IF, Confocal Microscopy
(). Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases. ACS Chem Neurosci.
Applications
Undefined
(). Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing's syndrome. bioRxiv Preprint
Applications
IF, Confocal Microscopy; IP, Co-IP; WB, IB, PCA
(). Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina. Cell Rep.
Applications
FC, FACS, FLOW
(). Avian ceca are indispensable for hindgut enteric nervous system development. Development.
Applications
Undefined
(). Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength. Development.
Applications
IP, Co-IP; WB, IB, PCA
(). A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos. Development.
Applications
IF, Confocal Microscopy
(). Cytomegalovirus subverts macrophage identity. Cell.
Applications
Undefined
(). Modulation of Sex Pheromone Discrimination by A UDP-Glycosyltransferase in Drosophila melanogaster. Genes
Applications
IF, Confocal Microscopy
(). Calsyntenin-3 directly interacts with neurexins to orchestrate excitatory synapse development in the hippocampus. bioRxiv
Applications
WB, IB, PCA; IF, Confocal Microscopy
(). Darbepoetin-α increases the blood volume flow in transplanted pancreatic islets in mice. Acta Diabetol.
Applications
IHC, ICC, Histology
(). Developing in vivo assays for investigation of p75NTR and NRH1 transmembrane domain cleavage events using zebrafish embryos. bioRxiv
Applications
WB, IB, PCA
(). Macrophages promote network formation and maturation of transplanted adipose tissue–derived microvascular fragments. SAGE Journals
Applications
IHC, ICC, Histology
(). α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity. J Cell Biol.
Applications
WB, IB, PCA
(). Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2. bioRxiv
Applications
WB, IB, PCA
(). Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer’s disease. ScienceDirect
Applications
WB, IB, PCA
(). Differential effects of SNARE-dependent gliotransmission on behavioral phenotypes in a mouse model of Huntington's disease. Exp Neurol.
Applications
IF, Confocal Microscopy
(). Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways. J Biol Chem.
Applications
WB, IB, PCA
(). Functional responses of the hippocampus to hyperexcitability depend on directed, neuron‐specific KCNQ2 K+ channel plasticity. Hippocampus.
Applications
IHC, ICC, Histology
(). Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastroinest Liver Physiol.
Applications
IHC, ICC, Histology
(). GABAergic restriction of network dynamics regulates interneuron survival in the developing cortex. Neuron.
Applications
IHC, ICC, Histology
(). Adhesion G-protein-coupled receptor, GPR56, is required for Müllerian duct development in the chick. J Endocrinol
Applications
IF, Confocal Microscopy
(). Aryl Hydrocarbon Receptor in Cutaneous Vascular Endothelial Cells Restricts Psoriasis Development by Negatively Regulating Neutrophil Recruitment. J Invest Dermatol
Applications
IF, Confocal Microscopy
(). Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation. J Biol Chem.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). A highly conserved circular RNA is required to keep neural cells in a progenitor state in the mammalian brain. Cell Rep
Applications
IF, Confocal Microscopy
(). Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release. Elife
Applications
IHC, ICC, Histology
(). GLP-1 Notch—LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1. PLoS Genet.
Applications
IP, Co-IP
(). A psychological stressor conveyed by appetite-linked neurons. Sci Adv.
Applications
IF, Confocal Microscopy
(). Insights into gonadal sex differentiation provided by single-cell transcriptomics in the chicken embryo. Cell Rep
Applications
IF, Confocal Microscopy
(). Reprogramming axial level identity to rescue neural-crest-related congenital heart defects. Dev Cell
Applications
IHC, ICC, Histology
(). Quantitative multiplexed proteomics of mouse microglia by flow-cytometric sorting reveals a core set of highly-abundant microglial proteins. Mol Neurodegener.
Applications
IF, Confocal Microscopy
(). Extraction of distinct neuronal cell types from within a genetically continuous population. Neuron.
Applications
IF, Confocal Microscopy
(). Cerebellospinal neurons regulate motor performance and motor learning. Cell Rep
Applications
IF, Confocal Microscopy
(). Epstein-Barr Virus LMP1 Promotes Syntenin-1-and Hrs-Induced Extracellular Vesicle Formation for Its Own Secretion To Increase Cell Proliferation and Migration. mBio.
Applications
WB, IB, PCA
(). Low‐dose rapamycin‐induced autophagy in cochlear outer sulcus cells. Laryngoscope Investig Ototlaryngol.
Applications
IF, Confocal Microscopy
(). Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer's disease. J Trace Elem Med Biol.
Applications
WB, IB, PCA
(). Downregulated miR-18b-5p triggers apoptosis by inhibition of calcium signaling and neuronal cell differentiation in transgenic SOD1 (G93A) mice and SOD1 (G17S and G86S) ALS patients. Transl Neurodegener.
Applications
WB, IB, PCA
(). FGF Pyramus Has a Transmembrane Domain and Cell-Autonomous Function in Polarity. Curr Biol.
Applications
IF, Confocal Microscopy
(). CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Nucleic Acids Res
Applications
IF, Confocal Microscopy
(). Mesenchymal niche-derived Neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles. BMC Mol Cell Biol.
Applications
WB, IB, PCA
(). Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration. Biomaterials.
Applications
FC, FACS, FLOW; IHC, ICC, Histology
(). The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neurosci Bull.
Applications
WB, IB, PCA
(). Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells. Neuron.
Applications
IHC, ICC, Histology
(). PIM1 Promotes Survival of Cardiomyocytes by Upregulating c-Kit Protein Expression. Cells.
Applications
WB, IB, PCA
(). Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons. Elife
Applications
Undefined
(). Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration. Elife
Applications
Undefined
(). A membrane-tethered ubiquitination pathway regulates Hedgehog signaling and heart development. Dev Cell
Applications
WB, IB, PCA
(). ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics. Neurochem Res.
Applications
Undefined
(). Genetically encoded tags for direct synthesis of EM-visible gold nanoparticles in cells. Nat Methods.
Applications
Immuno-EM
(). Protocol for Quantitative Analysis of Synaptic Vesicle Clustering in Axons of Cultured Neurons. STAR Protoc.
Applications
IHC, ICC, Histology
(). A C. elegans Zona Pellucida domain protein functions via its ZPc domain. PLoS Genet.
Applications
WB, IB, PCA
(). Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi. Proc Natl Acad Sci USA
Applications
IF, Confocal Microscopy
(). A FN-MdV pathway and its role in cerebellar multimodular control of sensorimotor behavior. Nat Commun.
Applications
IHC, ICC, Histology
(). Epstein-Barr virus LMP1 manipulates the content and functions of extracellular vesicles to enhance metastatic potential of recipient cells. Plos Pathog
Applications
WB, IB, PCA
(). Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep.
Applications
IHC, ICC, Histology
(). Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors. Cell Rep.
Applications
IHC, ICC, Histology
(). Prions induce minor genome-wide translational changes in neurons compared to glia. bioRxiv
Applications
IHC, ICC, Histology
(). The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets. Scientific Reports
Applications
IHC, ICC, Histology
(). Characterization of the role of Samsn1 loss in multiple myeloma development. Faseb BioAdvances
Applications
IHC, ICC, Histology
(). Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease. Cell Metab.
Applications
IP, Co-IP
(). Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene
Applications
IP, Co-IP; WB, IB, PCA
(). GFP-Fragment Reassembly Screens for the Functional Characterization of Variants of Uncertain Significance in Protein Interaction Domains of the BRCA1 and BRCA2 Genes. Cancers
Applications
WB, IB, PCA
(). Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues. Dev Cell.
Applications
IHC, ICC, Histology
(). An increase in neural stem cells and olfactory bulb adult neurogenesis improves discrimination of highly similar odorants. EMBO J.
Applications
IF, Confocal Microscopy
(). An improved method for bacterial immunofluorescence staining to eliminate antibody exclusion from the fixed nucleoid. Biochemistry.
Applications
IF, Confocal Microscopy
(). A novel function for the ER retention signals in the C-terminus of kainate receptor subunit, GluK5. Biochim Biophys Acta Mol Cell Res.
Applications
WB, IB, PCA
(). Transcriptional regulation of the Ciona Gsx gene in the neural plate. Dev Biol.
Applications
ISH, FISH
(). A complex between phosphatidylinositol 4-kinase IIα and integrin α3β1 is required for N-glycan sialylation in cancer cells. J Biol Chem.
Applications
WB, IB, PCA
(). BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation. Autophagy
Applications
IHC, ICC, Histology
(). Membrane-associated, not cytoplasmic or nuclear, fgfr1 induces neuronal differentiation. Cells.
Applications
Immuno-EM
(). A common embryonic origin of stem cells drives developmental and adult neurogenesis. Cell
Applications
IF, Confocal Microscopy
(). An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila. G3 (Bethesda).
Applications
IHC, ICC, Histology
(). Epigenomic profiling of retinal progenitors reveals LHX2 is required for developmental regulation of open chromatin. Commun Biol.
Applications
FC, FACS, FLOW
(). An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma. Elife
Applications
IP, Co-IP; WB, IB, PCA
(). The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons. J Comp Neurol.
Applications
IF, Confocal Microscopy
(). A subset of skin macrophages contributes to the surveillance and regeneration of local nerves. Immunity
Applications
IF, Confocal Microscopy
(). Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells. Gene Ther.
Applications
WB, IB, PCA
(). A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science
Applications
IF, Confocal Microscopy
(). The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury. Sci Rep.
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis. Cell Rep
Applications
WB, IB, PCA
(). Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA. Elife
Applications
IF, Confocal Microscopy; IHC, ICC, Histology
(). The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner. Cell Commun Signal
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Spatiotemporally dependent vascularization is differently utilized among neural progenitor subtypes during neocortical development. Cell Rep
Applications
IF, Confocal Microscopy
(). Expression of protein-coding gene orthologs in zebrafish and mouse inner ear non-sensory supporting cells. Front Neurosci.
Applications
IF, Confocal Microscopy
(). Conditional deletion of LRP1 leads to progressive loss of recombined NG2-expressing oligodendrocyte precursor cells in a novel mouse model. Cells.
Applications
IHC, ICC, Histology
(). Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder. Cell Rep
Applications
IF, Confocal Microscopy
(). Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1. Disease Models & Mechanisms
Applications
IHC, ICC, Histology
(). Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons. Cell Death & Disease
Applications
WB, IB, PCA
(). Perfringolysin O-Induced Plasma Membrane Pores Trigger Actomyosin Remodeling and Endoplasmic Reticulum Redistribution. Toxins
Applications
TEM
(). Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy. Frontiers in Neural Circuits
Applications
TEM; Immuno-EM; SEM
(). Alp7-Mto1 and Alp14 synergize to promote interphase microtubule regrowth from the nuclear envelope. Journal of Molecular Cell Biology
Applications
IP, Co-IP; WB, IB, PCA
(). T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. PloS Pathogens
Applications
IF, Confocal Microscopy
(). Local but not systemic administration of mesenchymal stromal cells ameliorates fibrogenesis in regenerating livers. J Cell Mol Med.
Applications
IHC, ICC, Histology
(). Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1 Journal of Virology
Applications
WB, IB, PCA
(). The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30. Molecular Cell
Applications
WB, IB, PCA
(). Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design. Molecules
Applications
WB, IB, PCA
(). Conditional mutagenesis in vivo reveals cell type- and infection stage-specific requirements for LANA in chronic MHV68 infection. PLOS Pathogens
Applications
IF, Confocal Microscopy
(). Coordination of olfactory receptor choice with guidance receptor expression and function in olfactory sensory neurons. PLOS Genetics
Applications
IHC, ICC, Histology
(). An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus. Stem Cell Reports
Applications
IHC, ICC, Histology
(). Mitofusin-Dependent ER Stress Triggers Glial Dysfunction and Nervous System Degeneration in a Drosophila Model of Friedreich's Ataxia. Frontiers in Molecular Neuroscience
Applications
IHC, ICC, Histology
(). Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. Elife
Applications
IHC, ICC, Histology; Multiplex Assay
(). Structural basis of the filamin A actin-binding domain interaction with F-actin. Nature Structural & Molecular Biology
Applications
WB, IB, PCA
(). Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36). Frontiers in Molecular Neuroscience
Applications
IF, Confocal Microscopy
(). Transmembrane Domains Mediate Intra- and Extracellular Trafficking of Epstein-Barr Virus Latent Membrane Protein 1. Journal of Virology
Applications
WB, IB, PCA
(). Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins. International Journal of Molecular Sciences
Applications
IHC, ICC, Histology
(). Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development. Journal of Experimental Medicine
Applications
IF, Confocal Microscopy
(). Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. Journal of Clinical Investigation
Applications
IF, Confocal Microscopy
(). Two Missense Variants Detected in Breast Cancer Probands Preventing BRCA2-PALB2 Protein Interaction. Frontiers in Oncology
Applications
WB, IB, PCA
(). Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med.
Applications
IF, Confocal Microscopy
(). Layer I Interneurons Sharpen Sensory Maps during Neonatal Development. Neuron.
Applications
IF, Confocal Microscopy
(). Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine. Addict Biol.
Applications
IHC, ICC, Histology
(). Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing. Nat Neurosci.
Applications
IHC, ICC, Histology
(). Graded arrays of spinal and supraspinal V2a interneuron subtypes underlie forelimb and hindlimb motor control. Neuron.
Applications
IHC, ICC, Histology
(). G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog. Sci Signal.
Applications
WB, IB, PCA
(). C33-A cells transfected with E6* I or E6* II the short forms of HPV-16 E6, displayed opposite effects on cisplatin-induced apoptosis. Virus Research
Applications
WB, IB, PCA
(). Combining high‐pressure freezing with pre‐embedding immunogold electron microscopy and tomography. Traffic.
Applications
TEM
(). Nuclear F-actin and myosins drive relocalization of heterochromatic breaks. Nature
Applications
IP, Co-IP
(). Toxoplasma ubiquitin-like protease 1, a key enzyme in sumoylation and desumoylation pathways, is under the control of non-coding RNAs. Int J Parasitol.
Applications
WB, IB, PCA
(). Deficiency of the Wnt receptor Ryk causes multiple cardiac and outflow tract defects. Growth Factors
Applications
IF, Confocal Microscopy
(). Development of novel amide-derivatized 2,4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a key modification. Eur J Med Chem.
Applications
WB, IB, PCA
(). Substrate priming enhances phosphorylation by the budding yeast kinases Kin1 and Kin2. J Biol Chem.
Applications
WB, IB, PCA
(). Identification of a Substrate-selective Exosite within the Metalloproteinase Anthrax Lethal Factor. Journal of Biological Chemistry
Applications
WB, IB, PCA
(). CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB Signaling. Journal of Virology
Applications
WB, IB, PCA
(). Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus. Journal of Biological Chemistry
Applications
WB, IB, PCA
(). Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice. F1000Research
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling. Molecular and Cellular Biology
Applications
WB, IB, PCA
(). Aberrant Transforming Growth Factor-β Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia. STEM CELLS Translational Medicine
Applications
IF, Confocal Microscopy; Multiplex Assay
(). The Dendrites of CA2 and CA1 Pyramidal Neurons Differentially Regulate Information Flow in the Cortico-Hippocampal Circuit. The Journal of Neuroscience
Applications
Immuno-EM
(). Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets. Cell Metabolism
Applications
Electrophysiology
(). An Intrinsic Epigenetic Barrier for Functional Axon Regeneration. Neuron
Applications
ISH, FISH
(). Comparative analysis of gene expression profiles for several migrating cell types identifies cell migration regulators. Mechanisms of Ageing and Development
Applications
ISH, FISH
(). Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature
Applications
IF, Confocal Microscopy
(). Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells. Scientific Reports
Applications
IHC, ICC, Histology
(). Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development
Applications
IHC, ICC, Histology
(). Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. Journal of Biological Chemistry
Applications
WB, IB, PCA
(). Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes. PLOS One
Applications
CLARITY, Two-Photon Microscopy
(). Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury. The Journal of Neuroscience
Applications
IHC, ICC, Histology
(). Novel ecto-tagged integrins reveal their trafficking in live cells. Nature Communications
Applications
WB, IB, PCA
(). Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding. Elife
Applications
IF, Confocal Microscopy
(). Olfactory sensory axons target specific protoglomeruli in the olfactory bulb of zebrafish. Neural Development
Applications
IHC, ICC, Histology
(). Programmed cell senescence in skeleton during late puberty. Nature Communications
Applications
IF, Confocal Microscopy
(). Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos. Nature Communications
Applications
IF, Confocal Microscopy
(). Foxp1 regulation of neonatal vocalizations via cortical development. Genes & Development
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity. PLOS One
Applications
IHC, ICC, Histology
(). Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair. Stem Cell Reports
Applications
IHC, ICC, Histology
(). Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs. Cell Reports
Applications
WB, IB, PCA
(). Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood. Acta Neuropathologica
Applications
IHC, ICC, Histology
(). Regulated viral BDNF delivery in combination with Schwann cells promotes axonal regeneration through capillary alginate hydrogels after spinal cord injury. Acta Biomater.
Applications
IHC, ICC, Histology
(). A coiled-coil strategy for the directional display of multiple proteins on the surface of iron oxide nanoparticles. Royal Society of Chemisty.
Applications
WB, IB, PCA
(). Flavin Adenine Dinucleotide and N5,N10‐Methenyltetrahydrofolate are the in planta Cofactors of Arabidopsis thaliana Cryptochrome 3. Photochem Photobiol.
Applications
WB, IB, PCA
(). The IQD family of calmodulin-binding proteins links calcium signaling to microtubules, membrane subdomains, and the nucleus. Plant Physiol.
Applications
IHC, ICC, Histology
(). The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells. Cell Signal
Applications
WB, IB, PCA
(). Structural insights into modulation of neurexin-neuroligin trans-synaptic adhesion by MDGA1/neuroligin-2 complex. Neuron.
Applications
IF, Confocal Microscopy
(). Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes. Cell Mol Life Sci.
Applications
TEM
(). Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins. Cell Stem Cell.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Distribution of corticotropin‐releasing factor (CRF) receptor binding in the mouse brain using a new, high‐affinity radioligand, [125I]‐PD‐Sauvagine. J Comp Neurol.
Applications
IHC, ICC, Histology
(). Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Dev Biol.
Applications
IF, Confocal Microscopy
(). Long-range GABAergic inputs regulate neural stem cell quiescence and control adult hippocampal neurogenesis. Cell Stem Cell
Applications
IF, Confocal Microscopy
(). A coiled-coil strategy for the directional display of multiple proteins on the surface of iron oxide nanoparticles. Royal Society of Chemistry
Applications
WB, IB, PCA
(). DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes. Cell
Applications
WB, IB, PCA
(). Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome. PloS One
Applications
WB, IB, PCA
(). Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. Journal of Virology
Applications
Ab Purification
(). PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape. Journal of Cell Science
Applications
WB, IB, PCA
(). Attractant and repellent cues cooperate in guiding a subset of olfactory sensory axons to a well-defined protoglomerular target. Development
Applications
IHC, ICC, Histology
(). A specific area of olfactory cortex involved in stress hormone responses to predator odours. Nature
Applications
IF, Confocal Microscopy
(). Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue - Evaluations on Monocyte-Based Delivery System for the Central Nervous System. PLOS One
Applications
WB, IB, PCA
(). RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nature Communications
Applications
IHC, ICC, Histology
(). ISG15 deficiency and increased viral resistance in humans but not mice. Nature Communications
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Cre-dependent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) mice. Genesis
Applications
IHC, ICC, Histology
(). LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia. Scientific Reports
Applications
IHC, ICC, Histology
(). LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia. Scientific Reports
Applications
IF, Confocal Microscopy; IHC, ICC, Histology; WB, IB, PCA
(). Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets. Molecular Metabolism
Applications
IF, Confocal Microscopy
(). Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation. The EMBO Journal
Applications
IHC, ICC, Histology
(). Integrity of Narrow Epithelial Tubes in the C. elegans Excretory System Requires a Transient Luminal Matrix. PLOS Genetics
Applications
WB, IB, PCA
(). A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research. G3: Genes, Genomes, Genetics
Applications
IHC, ICC, Histology
(). An oncogenic role for sphingosine kinase 2. Oncotarget
Applications
FC, FACS, FLOW
(). Intramolecular hydrophobic interactions are critical mediators of STAT5 dimerization. Scientific Reports
Applications
WB, IB, PCA
(). Cell type-specific bipolar cell input to ganglion cells in the mouse retina. Neuroscience
Applications
IHC, ICC, Histology
(). Analysis of Hippo and TGFβ signaling in polarizing epithelial cells and mouse embryos. Differentiation
Applications
IF, Confocal Microscopy
(). Post-transcriptional regulation mediated by specific neurofilament introns in vivo. J Cell Sci
Applications
IHC, ICC, Histology
(). Physiological function and inflamed-brain migration of mouse monocyte-derived macrophages following cellular uptake of superparamagnetic iron oxide nanoparticles-Implication of macrophage-based drug delivery into the central nervous system. Int J Pharm.
Applications
IF, Confocal Microscopy
(). Dissecting functions of the N-terminal domain and GAS-site recognition in STAT3 nuclear trafficking. Cell Signal.
Applications
IP, Co-IP
(). A molecular imaging biosensor detects in vivo protein folding and misfolding. J Mol Med (Berl).
Applications
WB, IB, PCA
(). Sortilin is a Negative Regulator of Sonic Hedgehog Processing and Anterograde Trafficking in Neurons. J Cell Sci
Applications
WB, IB, PCA
(). A Bone–Implant Interaction Mouse Model for Evaluating Molecular Mechanism of Biomaterials/Bone Interaction. Tissue Eng Part C Methods.
Applications
IHC, ICC, Histology
(). Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations. Journal of Biological Chemistry
Applications
IP, Co-IP
(). Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK). Cell Communication and Signaling
Applications
IF, Confocal Microscopy; IP, Co-IP; WB, IB, PCA
(). Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System. Traffic
Applications
Immuno-EM
(). In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb. Nature Communications
Applications
IHC, ICC, Histology
(). 10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A. Journal of Medicinal Chemistry
Applications
WB, IB, PCA
(). Analysis of soluble protein entry into primary cilia using semipermeabilized cells. Methods in Cell Biology
Applications
IF, Confocal Microscopy
(). Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms. mBio
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). Comparative Analysis of Transmembrane Regulators of the Filamentous Growth Mitogen-Activated Protein Kinase Pathway Uncovers Functional and Regulatory Differences. Eukaryotic Cell
Applications
IP, Co-IP
(). Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis. Cell Stem Cell
Applications
IHC, ICC, Histology
(). Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment. Journal of Biological Chemistry
Applications
WB, IB, PCA
(). MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Molecular Biology of the Cell
Applications
WB, IB, PCA
(). PTEN regulates cilia through Dishevelled. Nature Communications
Applications
IF, Confocal Microscopy
(). Heterochromatic breaks move to the nuclear periphery to continue recombinational repair. Nature Cell Biology
Applications
IP, Co-IP
(). Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation. Nature Neuroscience
Applications
IHC, ICC, Histology
(). Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis. The American Journal of Pathology
Applications
IHC, ICC, Histology
(). Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication. Journal of Virology
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). Survival of irradiated recipient mice after transplantation of bone marrow from young, old and "early aging" mice. Aging
Applications
IHC, ICC, Histology
(). Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling. PLOS Genetics
Applications
IF, Confocal Microscopy
(). Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci USA.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage. Journal of Neuroinflammation
Applications
IF, Confocal Microscopy
(). A reduction in Npas4 expression results in delayed neural differentiation of mouse embryonic stem cells. Stem Cell Research & Therapy
Applications
WB, IB, PCA
(). Morphological and physiological properties of enhanced green fluorescent protein (EGFP)-expressing wide-field amacrine cells in the ChAT-EGFP mouse line. Eur J Neurosci.
Applications
IHC, ICC, Histology
(). Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. PLoS Genet.
Applications
WB, IB, PCA
(). Characterization of an Italian founder mutation in the RING-finger domain of BRCA1. PLoS One
Applications
WB, IB, PCA
(). De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome. Nat Genet.
Applications
IHC, ICC, Histology
(). Characterization of a homolog of DEAD-box RNA helicases in Toxoplasma gondii as a marker of cytoplasmic mRNP stress granules. Gene.
Applications
WB, IB, PCA
(). Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature
Applications
IHC, ICC, Histology
(). RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast. Nature
Applications
WB, IB, PCA
(). Ntf3 acts downstream of Sip1 in cortical postmitotic neurons to control progenitor cell fate through feedback signaling. Development
Applications
IF, Confocal Microscopy
(). Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell.
Applications
FC, FACS, FLOW; IF, Confocal Microscopy
(). 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci
Applications
IF, Confocal Microscopy
(). Nerve fiber layer thinning lags retinal ganglion cell density following crush axonopathy. Invest Ophthamol Vis Sci.
Applications
IF, Confocal Microscopy
(). A non-cell-autonomous role for Ras signaling in C. elegans neuroblast delamination. Development
Applications
IF, Confocal Microscopy
(). Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development. Glia.
Applications
IHC, ICC, Histology
(). Synaptic elements for GABAergic feed-forward signaling between HII horizontal cells and blue cone bipolar cells are enriched beneath primate S-cones. PloS One
Applications
IF, Confocal Microscopy
(). Generation of unique poliovirus RNA replication organelles. MBio
Applications
Immuno-EM
(). A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans. Developmental Biology
Applications
IF, Confocal Microscopy
(). Rage signalling promotes intestinal tumourigenesis. Oncogene
Applications
IHC, ICC, Histology
(). Incorporation of bone marrow cells in pancreatic pseudoislets improves posttransplant vascularization and endocrine function. PLoS One.
Applications
IHC, ICC, Histology
(). ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. J Biol Chem.
Applications
WB, IB, PCA
(). Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit. Gastroenterology
Applications
IF, Confocal Microscopy
(). Development of myenteric cholinergic neurons in ChAT‐Cre;R26R‐YFP mice. J Comp Neurol.
Applications
IHC, ICC, Histology
(). Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons. PLoS One
Applications
IHC, ICC, Histology; IP, Co-IP; WB, IB, PCA
(). Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replication. Plos Pathog
Applications
FC, FACS, FLOW
(). Filamin A regulates neuronal migration through brefeldin A-inhibited guanine exchange factor 2-dependent Arf1 activation. J Neurosci
Applications
IHC, ICC, Histology
(). An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol.
Applications
IF, Confocal Microscopy
(). Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma. Cancer Metab.
Applications
IHC, ICC, Histology; WB, IB, PCA
(). Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules. Proc Natl Acad Sci U S A.
Applications
Bead Conjugation
(). Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity. The Journal of Cell Biology
Applications
IF, Confocal Microscopy
(). Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb. J Neurosci.
Applications
IHC, ICC, Histology; ISH, FISH
(). Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin. EMBO J.
Applications
Immuno-EM; WB, IB, PCA
(). Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. J Neurosci
Applications
IHC, ICC, Histology
(). The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization. J Cell Biol.
Applications
WB, IB, PCA
(). Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell.
Applications
IF, Confocal Microscopy; IP, Co-IP
(). Using superfolder green fluorescent protein for periplasmic protein localization studies. J Bacteriol.
Applications
WB, IB, PCA
(). Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina. J Comp Neurol.
Applications
IHC, ICC, Histology
(). Expression and function of Sox21 during mouse cochlea development. Neurochem Res.
Applications
IHC, ICC, Histology
(). The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development (Cambridge, England)
Applications
IHC, ICC, Histology
(). Multicolor BiFC analysis of G protein βγ complex formation and localization. Methods in Molecular Biology (Clifton, N.J.)
Applications
Electronic Absorption and Fluorescence Spectroscopy
(). CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2. PloS Genetics
Applications
WB, IB, PCA
(). Localization of the calcium‐binding protein secretagogin in cone bipolar cells of the mammalian retina. J Comp Neurol.
Applications
IHC, ICC, Histology
(). The calmodulin-stimulated adenylate cyclase ADCY8 sets the sensitivity of zebrafish retinal axons to midline repellents and is required for normal midline crossing. J Neurosci
Applications
IHC, ICC, Histology
(). Expression profile and protein translation of TMEM16A in murine smooth muscle. Am J Physiol Cell Physiol.
Applications
WB, IB, PCA
(). Intracellular membrane traffic at high resolution. Methods Cell Biol.
Applications
Immuno-EM; TEM
(). Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas. Bmc Developmental Biology
Applications
IF, Confocal Microscopy
(). An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. The Journal of Cell Biology
Applications
Immuno-EM
(). TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans. PloS One
Applications
IF, Confocal Microscopy
(). A bacterial signal peptide is functional in plants and directs proteins to the secretory pathway. J Exp Bot.
Applications
WB, IB, PCA
(). Implanted adult human dental pulp stem cells induce endogenous axon guidance. Stem Cells
Applications
IF, Confocal Microscopy
(). A novel type of interplexiform amacrine cell in the mouse retina. Eur J Neurosci.
Applications
IHC, ICC, Histology
(). High throughput functional assays of the variant antigen PfEMP1 reveal a single domain in the 3D7 Plasmodium falciparum genome that binds ICAM1 with high affinity and is targeted by naturally acquired neutralizing antibodies. PloS Pathogens
Applications
Ab Immobilization
(). Dorsoventral patterning of the C. elegans postembryonic mesoderm requires both LIN-12/Notch and TGFbeta signaling. Dev Biol.
Applications
IF, Confocal Microscopy
(). Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues. Stem Cells
Applications
IF, Confocal Microscopy
(). Type 1 corticotropin-releasing factor receptor expression reported in BAC transgenic mice: implications for reconciling ligand-receptor mismatch in the central corticotropin-releasing factor system. J Comp Neurol.
Applications
IF, Confocal Microscopy; WB, IB, PCA
(). Diversity of glycine receptors in the mouse retina: localization of the α4 subunit. J Comp Neurol.
Applications
IHC, ICC, Histology
(). Glycine receptors of A-type ganglion cells of the mouse retina. Vis Neurosci.
Applications
IHC, ICC, Histology
(). Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury. Circulation
Applications
IF, Confocal Microscopy
(). Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3. Mol Cancer Res.
Applications
IP, Co-IP
(). Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs. Journal of Applied Physiology
Applications
IHC, ICC, Histology
(). Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain. Gene Ther.
Applications
EIA, ELISA

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