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Datasheet

Neuroligin 1 Antibody Peroxidase

Mouse Monoclonal S97A-31 IgG1

200-303-W75
100 µg
WB, IHC
Human, Mouse, Rat
Mouse
$495.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion.

Product Details

Anti-Neuroligin 1 (MOUSE) Monoclonal Antibody Peroxidase Conjugated - 200-303-W75
NLG 1, KIAA1070, MGC45115, Neuroligin-1, NL1, NLG1, Nlgn1
Mouse
Peroxidase (HRP)
Monoclonal
IgG1

Target Details

Nlgn1  - View All Nlgn1 Products
Human, Mouse, Rat
Recombinant Protein
Anti-Neuroligin 1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 718-843 of rat Neuroligin-1.
Anti-Neuroligin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 99% identical to mouse, 99% identical to human and >50% identical to Neuroligin-2 and -3.

Application Details

IHC, WB
Anti-Neuroligin 1 HRP Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~120kDa on specific lysates or tissues. Does not cross react with other Neuroligins. Specific conditions for reactivity should be optimized by the end user.

Formulation

Liquid (sterile filtered)
1mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.1% (w/v) Sodium Azide
50% (v/v) Glycerol

Shipping & Handling

Wet Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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