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rMouse PDGF-AA Protein
Description
Background
Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-α, TGF-β and EGF. Recombinant mouse PDGF-AA is a non-glycosylated, disulfide-linked homodimer, containing two 126 amino acid chains, with a total molecular weight of 28.9 kDa.
Application Note
Platelet Derived Growth Factor-AA Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Platelet Derived Growth Factor-AA in immunological assays.
Purity/Specificity
platelet Derived Growth Factor AA purity was determined to be greater than 97% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
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