rHuman SDF-1 alpha/CXCL12 Protein
Background
Stromal cell Derived Factor-1 alpha (SDF-1α), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1α signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human and mouse SDF-1α share 99% sequence identity. Recombinant human SDF-1α is a non-glycosylated protein, containing 68 amino acids, with a molecular weight of 8 kDa.
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