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rHuman ITAC (CXCL11) Protein
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Description
Background
Interferon Inducible T cell Alpha Chemokine (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNα, β, and γ. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Recombinant human I-TAC is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 8.3 kDa.
Application Note
ITAC Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-ITAC in immunological assays.
Purity/Specificity
ITAC (CXCL11) purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.