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Thrombin Heavy Chain Antibody

Rabbit Polyclonal

100 µL
Human, Mouse, Rat
$429.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.


Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets. The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin. Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates and although many structures of thrombin have been solved few such interactions have been described in molecular detail. Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin.

Product Details

Anti-Thrombin Heavy Chain (AA 551-622) Antibody - ABIN736298
PT, THPH1, RPRGL2, coagulation factor II, prothrombin F2, Cf-2, Cf2, FII, F 2, coagulation factor II, thrombin Coagulation factor II, Coagulation factor II, precursor F2, Factor II, Factor-II, Prothrombin, prothrombin B-chain, PT, serine protease, THRB, THRB_HUMAN, Thrombin, Thrombin heavy chain

Target Details

Human, Mouse, Rat
Conjugated Peptide
KLH conjugated synthetic peptide derived from human Thrombin heavy chain. [AA 551-622]
Purified by Protein A. A BLAST analysis was used to suggest reactivity with this protein from Cow, Pig, Horse, Chicken, Rabbit, and Fish.

Application Details

Anti-Thrombin Heavy Chain (AA 551-622) Antibody is tested for use in ELISA, Immunofluorescence (Cultured Cells) (IF-CC), Immunofluorescence (Paraffin-embedded (IF-P), Immunohistochemistry (Frozen Sections) (IHC-F), and Immunohistochemistry (Paraffin-embedded) (IHC-P). Subcellular location: Secreted Extracellular matrix. This product is in 0.01M TBS pH7.4.


Proclin is added as an antimicrobial agent.
50% (v/v) Glycerol

Shipping & Handling

Wet Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use. Stable for 12 months from date of receipt.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.