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            Seasonal H1N1 Nonstructural Protein 1 Antibody
Rabbit Polyclonal
            
                600-401-EG3
        
        
            
                100 µg
        
            
                
                    Liquid (sterile filtered)
            
            
                
                ELISA
            
                    
                
                Virus
            
                            
                
                 Rabbit
            
                
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Anti-Seasonal H1N1 Nonstructural Protein 1 (RABBIT) Antibody - 600-401-EG3                    
                
                
                    
                    
Seasonal H1N1 Nonstructural Protein 1 Antibody                    
                
                
                    
                    
Rabbit                    
                
                
                    
                    
Polyclonal                    
                
                
                    
                    
IgG                    
                
            Target Details
                    
                    
NS1                         - View All NS1 Products
                            
                    
                
                
                    
                    
Virus                                            
                
                
                    
                    
Conjugated Peptide                                            
                
                
                    
                    
Anti-NS1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide from. The seasonal Influenza NS1 protein.                                            
                
                
                    
                    
Anti-Seasonal H1N1 Nonstructural Protein 1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for the seasonal H1N1 influenza NS1 and will not recognize the corresponding NS1 sequence from the Swine-Origin H1N1 influenza (A/California/04/2009 (H1N1)).                                            
                
                
                Application Details
                        
                        
ELISA
                        
                    
                    
                        
                        
Anti-Seasonal H1N1 Nonstructural Protein 1 Antibody has been tested for use in ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 26 kDa in Western Blots of specific cell lysates and tissues.
                        
                    
                                                    Formulation
                        
                        
1 mg/mL by UV absorbance at 280 nm                        
                    
                    
                        
                        
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2                        
                    
                    
                        
                        
0.02% (w/v) Sodium Azide                        
                    
                    
                        
                        
None                        
                    
            Shipping & Handling
                    
                    
Wet Ice                    
                
                
                    
                    
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.                    
                
                
                    
                    
Expiration date is one (1) year from date of receipt.                    
                
        
                Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2´-5´OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
            
        
            This product is for research use only and is not intended for therapeutic or diagnostic applications.  Please contact a technical service representative for more information.  All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin.  Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.  All properties listed are typical characteristics and are not specifications.  All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control.  All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale.  Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc.  If you require a commercial license to use this material and do not have one, then return this material, unopened to:  Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.