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Datasheet

Retinoid X Receptor gamma Antibody

Mouse Monoclonal 1373 IgG1

209-301-E28
100 µL
WB
Human, Rat
Mouse
$485.00 /Per Item
Availability: Ships in approximately 14 days
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Background

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Product Details

Anti-Retinoid X Receptor gamma (MOUSE) Monoclonal Antibody - 209-301-E28
mouse anti-Retinoid X Receptor gamma Antibody, mouse anti-RXRG antibody, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma
Mouse
Monoclonal
IgG1

Target Details

RXRG  - View All RXRG Products
Human, Rat
Conjugated Peptide
Anti-Retinoic Acid Receptor gamma was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the hinged region of RAR-γ.
Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma. Retinoic Acid Receptor gamma antibody was Protein G purified from cell culture supernatant. This antibody is directed against human retinoic acid receptor gamma protein. Reactivity is expected from the following species based on 100% sequence homology: bovine, mouse, non-human primate and rat. Cross reactivity to other sources has not been tested.

Application Details

WB
Anti-Retinoid X Receptor gamma antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-γ isotype in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Formulation

Liquid
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.