Quick Order
Retinoic Acid Receptor beta Antibody
Mouse Monoclonal 336 IgG1
$50.00 to US & Canada for most products. Final costs are calculated at checkout.
Description
Background
Retinoic Acid Receptor beta antibody detects RAR beta. Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Application Note
Anti-Retinoic Acid Receptor beta antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to expected molecular weight for RAR-β proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
Purity/Specificity
Anti-Retinoic Acid Receptor beta antibody detects Retinoic Acid Receptor beta. Retinoic Acid Receptor beta antibodies was Protein G purified from cell culture supernatant. This antibody is directed against human retinoic acid receptor beta protein. Expect reactivity with RAR beta from the following species is predicted based on 100% sequence homology: canine, guinea pig, mouse, rat, non-human primate. Cross reactivity from other sources has not been determined.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.