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Datasheet

ORAI2 Antibody

Rabbit Polyclonal

600-401-H07
100 µg
WB, ELISA, IHC, IF
Human, Mouse
Rabbit
$475.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

ORAI2 antibody detects human ORAI. Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3. Anti-ORAI2 antibodies are ideal for investigators involved cell cycle protein and enzyme research.

Product Details

Anti-ORAI2 (RABBIT) Antibody - 600-401-H07
Protein orai-2, CAP-binding protein complex-interacting protein 2, Transmembrane protein 142B, ORAI2, C7orf19, CBCIP2, TMEM142B, PP1729
Rabbit
Polyclonal
IgG

Target Details

ORAI2  - View All ORAI2 Products
Human, Mouse
Conjugated Peptide
ORAI2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide near the c-terminus of human ORAI2.
Anti-ORAI2 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with ORAI2 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with ORAI2 from other sources has not been determined.

Application Details

ELISA, IF, IHC, WB
Anti-ORAI2 Antibody is tested for use in E, WB, IF, and ICC. Expect a band approximately ~28.5 kDa on specific lysates. Western Blot, Immunocytochemistry, and Immunofluorescence tested in human samples. Specific conditions for reactivity should be optimized by the end user.

Formulation

Liquid (sterile filtered)
1 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.