Nur77 Antibody
Rabbit Polyclonal IgG
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Background
Anti Nur7 antibody detects human Nur77. Nur77 (Nak-1,TR3) is a member of the NR4A orphan nuclear receptor (NR) superfamily of transcription factors. The Nur77 ligand has not yet been identified. It is thought that the lack of ability to identify a ligand may be due to the lack of a typical NR binding pocket in the ligand binding domain. Nur77, like other NR4A receptors, are immediate-early genes induced by diverse stimuli in multiple tissues. There is increasing evidence that Nur77 and other NR4A receptors play important roles in maintaining tissue homeostasis. For example, specific Nur77 functions have been defined in the brain, T-cells/thymocytes, adipose tissue, steroidgenesis, muscle, blood vessels, macrophages and cardiovascular system. There is also evidence that Nur77 plays roles in pathological processes such as cancer. Nur77 is a phosphoprotein and its size ranges from ~65 kDa to 90 kDa depending on the isoform expressed and level of phosphorylation or other post-translational modifications. Anti-Nur77 antibody is ideal for investigators involved in apoptosis.
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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.