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            Mre11 Antibody
Rabbit Polyclonal
            
                600-401-872
        
        
            
                100 µg
        
            
                
                    Liquid (sterile filtered)
            
            
                
                ELISA, ChIP
            
                    
                
                S. cerevisiae
            
                            
                
                 Rabbit
            
                
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Anti-Mre11 (S. cerevisiae) (RABBIT) Antibody - 600-401-872                    
                
                
                    
                    
rabbit anti-Mre11 antibody, Double-strand break repair protein MRE11, DNA recombination and repair protein, Meiotic recombination 11                    
                
                
                    
                    
Rabbit                    
                
                
                    
                    
Polyclonal                    
                
                
                    
                    
IgG                    
                
            Target Details
                    
                    
MRE11                         - View All MRE11 Products
                            
                    
                
                
                    
                    
S. cerevisiae                                            
                
                
                    
                    
Conjugated Peptide                                            
                
                
                    
                    
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 575-600 of Saccharomyces cerevisiae (baker´s yeast) Mre11 protein.                                            
                
                
                    
                    
This affinity-purified antibody is directed against Saccharomyces cerevisiae Mre11 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest that little cross reactivity should be expected with this protein from other sources.                                            
                
                
                Application Details
                        
                        
ChIP, ELISA
                        
                    
                    
                        
                        
This affinity purified antibody has been tested for use in ELISA and by ChIP assay.  Specific conditions for reactivity should be optimized by the end user.
                        
                    
                                                    Formulation
                        
                        
1.17 mg/mL by UV absorbance at 280 nm                        
                    
                    
                        
                        
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2                        
                    
                    
                        
                        
0.01% (w/v) Sodium Azide                        
                    
                    
                        
                        
None                        
                    
            Shipping & Handling
                    
                    
Dry Ice                    
                
                
                    
                    
Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.                     
                
                
                    
                    
Expiration date is one (1) year from date of receipt.                    
                
        
                Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability.  Mre11 possesses single-strand endonuclease activity and double-strand-specific 3´-5´ exonuclease activity that appears to be required for RMX function.  This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.
            
        
            This product is for research use only and is not intended for therapeutic or diagnostic applications.  Please contact a technical service representative for more information.  All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin.  Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.  All properties listed are typical characteristics and are not specifications.  All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control.  All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale.  Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc.  If you require a commercial license to use this material and do not have one, then return this material, unopened to:  Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.