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Kv1.1 Extracellular Antibody
Mouse Monoclonal S36-15 IgG2b
200-301-F91
100 µg
Liquid (sterile filtered)
WB, IHC
Mouse, Rat
Mouse
This product is discontinued
Product Details
Anti-Kv1.1 Extracellular (MOUSE) Monoclonal Antibody - 200-301-F91
KCA1, KCNA1, MBK1, MK1, RBK1, Shak, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage gated channel subfamily A member 1, RBKI, RCK1
Mouse
Monoclonal
IgG2b
Target Details
Kcna1 - View All Kcna1 Products
Mouse, Rat
Conjugated Peptide
Kv1.1 Extracellular Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at an extracellular domain of rat Kv1.1.
Anti-Kv1.1 Extracellular Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.1 from Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.1 from other sources has not been determined. Ion Channels research.
P10499 - UniProtKB
NP_775118.1 - NCBI Protein
Application Details
IHC, WB
Anti-Kv1.1 Extracellular Antibody is tested for use in WB and IF microscopy. Expect a band approximately ~56kDa (could be 65-85 depending on glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.0 mg/ml by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
50% (v/v) Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.