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Datasheet

Gelsolin Antibody

Mouse Monoclonal GS-2C4 IgG1

200-301-P37
100 µg
WB, IHC
Human, Rabbit
Mouse
$485.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

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Background

Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. This antibody is suitable for researchers interested in cell research and cytoskeletal signaling research.

Product Details

Anti-Gelsolin (MOUSE) Antibody - 200-301-P37
AGEL, ADF, Brevin, Actin-depolymerizing factor
Mouse
Monoclonal
IgG1

Target Details

GSN  - View All GSN Products
Human, Rabbit
Other
Gelsolin antibody was produced in mice by repeated immunizations with human plasma gelsolin.
Anti-Gelsolin antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human and rabbit. Cross reactivity with Gelsolin from other sources has not been determined.

Application Details

IHC, WB
Anti-Gelsolin is tested for Immunohistochemistry -P, -F and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~85.7 kDa corresponding to the appropriate cell lysate or extract.

Formulation

Lyophilized
1.0 mg/mL by UV absorbance at 280 nm
1.2% sodium acetate
0.01% (w/v) Sodium Azide
2mg BSA
1.0 mL
Neutral PBS

Shipping & Handling

Ambient
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.