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Datasheet

FTO Antibody

Mouse Monoclonal 5-2H10 IgG

200-301-D41
100 µL
WB
Human, Mouse, Rat
Mouse
$485.00 /Per Item
Availability: Ships in approximately 14 days
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Background

FTO Antibody detects human FTO which is the protein encoded by FTO gene that is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake. Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure. Anti-FTO Antibody is ideal for investigators involved in Neuroscience and Cell Metabolism.

Product Details

Anti-FTO (Fat mass and obesity related protein) (MOUSE) Monoclonal Antibody - 200-301-D41
Alpha-ketoglutarate-dependent dioxygenase FTO, KIAA1752
Mouse
Monoclonal
IgG

Target Details

FTO  - View All FTO Products
Human, Mouse, Rat
Conjugated Peptide
Anti-FTO Monoclonal Antibody was produced in mouse by repeated immunizations with FTO- Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
Anti-FTO antibody is directed against human Fat mass and Obesity Related Protein. Anti-FTO is a Protein G purified antibody from cell culture supernatant. Reactivity is expected with the following species based on 100% sequence homology: bovine, canine, horse, non-human primate, sheep.

Application Details

WB
Anti-FTO (Mouse) Antibody has been tested in Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 58 kDa in size corresponding to FTO proteins in Western blots of rat testes lysate. This antibody has also been used for immunocytochemistry with neuronal progenitor cells.

Formulation

Liquid
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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