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            DOCK8 Antibody
Rabbit Polyclonal
            
                600-401-AW8
        
        
            
                100 µg
        
            
                
                    Liquid (sterile filtered)
            
            
                
                WB, ELISA, IHC
            
                    
                
                Human, Mouse, Rat
            
                            
                
                 Rabbit
            
                
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Anti-DOCK8 (RABBIT) Antibody - 600-401-AW8                    
                
                
                    
                    
DOCK8 Antibody, MRD2, ZIR8, HEL-205, Dedicator of cytokinesis protein 8                    
                
                
                    
                    
Rabbit                    
                
                
                    
                    
Polyclonal                    
                
                
                    
                    
IgG                    
                
            Target Details
                    
                    
DOCK8                         - View All DOCK8 Products
                            
                    
                
                
                    
                    
Human, Mouse, Rat                                            
                
                
                    
                    
Conjugated Peptide                                            
                
                
                    
                    
Anti-DOCK8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human DOCK8.                                            
                
                
                    
                    
Anti-DOCK8 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.                                            
                
                
                Application Details
                        
                        
ELISA, IHC, WB
                        
                    
                    
                        
                        
Anti-DOCK8 Antibody has been tested for use in ELISA, Western Blotting, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 239 kDa in Western Blots of specific cell lysates and tissues.
                        
                    
                                                    Formulation
                        
                        
1 mg/mL by UV absorbance at 280 nm                        
                    
                    
                        
                        
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2                        
                    
                    
                        
                        
0.02% (w/v) Sodium Azide                        
                    
                    
                        
                        
None                        
                    
            Shipping & Handling
                    
                    
Dry Ice                    
                
                
                    
                    
Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.                    
                
                
                    
                    
Expiration date is one (1) year from date of receipt.                    
                
        
                The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2).  Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).
            
        
            This product is for research use only and is not intended for therapeutic or diagnostic applications.  Please contact a technical service representative for more information.  All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin.  Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.  All properties listed are typical characteristics and are not specifications.  All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control.  All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale.  Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc.  If you require a commercial license to use this material and do not have one, then return this material, unopened to:  Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.