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            Cyclin T2 Antibody
Rabbit Polyclonal
            
                100-401-931
        
        
            
                100 µL
        
            
                
                    Liquid (sterile filtered)
            
            
                
                WB, ELISA
            
                    
                
                Human
            
                            
                
                 Rabbit
            
                
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Anti-Cyclin T2 (RABBIT) Antibody - 100-401-931                    
                
                
                    
                    
rabbit anti-Cyclin T2 antibody, CycT2                    
                
                
                    
                    
Rabbit                    
                
                
                    
                    
Polyclonal                    
                
                
                    
                    
Antiserum                    
                
            Target Details
                    
                    
CCNT2                         - View All CCNT2 Products
                            
                    
                
                
                    
                    
Human                                            
                
                
                    
                    
Recombinant Protein                                            
                
                
                    
                    
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 1-584 of human Cyclin T2a protein.                                            
                
                
                    
                    
This antibody is directed against human Cyclin T2 proteins and was prepared from monospecific antiserum by delipidation and defibrination.  Antiserum will specifically react with proteins 74 and 81 kDa in size corresponding to isoforms of Cyclin T2 protein by western blot.  A protein:protein BLAST analysis was used to suggest cross reactivity with Cyclin T2a and T2b from dog (96%), bovine (93%), mouse (88%) and rat (85%) sources based on high homology with the full length protein.  Reactivity against homologues from other sources is not known.                                            
                
                Application Details
                        
                        
ELISA, WB
                        
                    
                    
                        
                        
This antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect bands approximately 74 and 81 kDa in size corresponding to isoforms of Cyclin T2 protein by western blotting in the appropriate tissue or cell lysate or extract.
                        
                    
                                                    Formulation
                        
                        
85 mg/mL by Refractometry                        
                    
                    
                        
                        
None                        
                    
                    
                        
                        
0.01% (w/v) Sodium Azide                        
                    
                    
                        
                        
None                        
                    
            Shipping & Handling
                    
                    
Dry Ice                    
                
                
                    
                    
Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.                     
                
                
                    
                    
Expiration date is one (1) year from date of receipt.                    
                
        
                Cyclin T2 is a ubiquitously expressed nuclear protein that is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns that contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Anti-Cyclin T2 Antibody is useful for researchers interested in HIV research, Gene expression, and cell cycle pathways.
            
        
            This product is for research use only and is not intended for therapeutic or diagnostic applications.  Please contact a technical service representative for more information.  All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin.  Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.  All properties listed are typical characteristics and are not specifications.  All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control.  All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale.  Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc.  If you require a commercial license to use this material and do not have one, then return this material, unopened to:  Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.