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Datasheet

CRP Antibody

Goat Polyclonal

209-1132 209-1132S 209-1132-0100
50 mg 25 µL 100 µg
Lyophilized Liquid (sterile filtered) Lyophilized
WB, Dot Blot
Human
Goat
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$125.00 /Per Item
$475.00 /Per Item
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Product Details

Anti-Human CRP (GOAT) Antibody (BULK ORDER) - 209-1132
goat anti-CRP Antibody, C reactive protein pentraxin related antibody, CRP antibody, MGC88244 antibody, PTX 1 antibody, PTX1 antibody
Goat
Polyclonal
IgG

Target Details

CRP  - View All CRP Products
Human
Native Protein
Capsular Reactive Protein (CRP) [Human Serum]
This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Capsular Reactive Protein (CRP) [Human Serum].  Cross reactivity against Capsular Reactive Protein (CRP) from other tissues and species may occur but have not been specifically determined.
P02741 - UniProtKB
NP_000558.2 - NCBI Protein
1401 - Gene ID

Application Details

Dot Blot, WB
Anti-CRP Antibody has been tested by dot blot and western blot and is suitable for ELISA and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.

Formulation

10.0 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None
5.0 mL
Restore with deionized water (or equivalent)

Shipping & Handling

Ambient
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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