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Coagulation Factor VII Antibody

Rabbit Polyclonal

100 µL
Human, Mouse
$565.00 /Per Item
Availability: Ships in approximately 14 days
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.


This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by either factor IXa factor Xa factor XIIa or thrombin by minor proteolysis. Upon activation of the factor VII a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.

Product Details

Anti-Coagulation Factor VII (F7) (Center) Antibody - ABIN2854983
coagulation factor VII, F7, wu:fb59f04, zgc:109870, SPCA, AI114908, ATIII, At-3, At3, LOC100223776, AI132620, Cf7, FVII, mfVII, f7, coagulation factor VII, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog, F7, f7, Serpinc1, CpipJ_CPIJ009142, CpipJ_CPIJ010295, CpipJ_CPIJ020127, fa7, f7.S

Target Details

Human, Mouse
Recombinant Protein
Recombinant protein encompassing a sequence within the center region of human Factor VII. The exact sequence is proprietary.
Rabbit polyclonal antibody to Factor VII (coagulation factor VII (serum prothrombin conversion accelerator)) Factor VII antibody [N3C3] has been purified by antigen-affinity chromatography.

Application Details

Anti-Coagulation Factor VII (F7) (Center) Antibody is tested for use in Immunohistochemistry (Paraffin-embedded Sections) (IHC-P) and Western Blotting (WB). Cellular Localization: Secreted. Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000*. Expect a band approximately 52kDa in size corresponding to Factor VII by western blotting in the appropriate cell lysate or extract. Western blot 1:500-1:3000*. Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher. Positive Control: human plasma NIH-3T3. This product is in 0.1M Tris, 0.1M Glycine Buffer.


0.74 mg/mL by UV absorbance at 280 nm
0.01% (w/v) Thimerosal
10% (v/v) Glycerol

Shipping & Handling

Wet Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use. Stable for 12 months from date of receipt.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.