CD4 Fluorescein Antibody
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Datasheet

CD4 Fluorescein Antibody

Rat Monoclonal GK1.5 IgG2b kappa

200-502-M70
500 µg
Mouse
Rat
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$318.00 /Per Item
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Description

Background

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Application Note

Anti-CD4 is useful for Immunofluorescence and Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

Purity/Specificity

Fluorescein conjugated CD4 Monoclonal Antibody was Protein G Purified and is directed against mouse CD4. Reactivity is observed against mouse CD4. Cross reactivity with CD4 from other sources has not been tested.

Storage Condition

Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Anti-CD4 (RAT) Monoclonal Antibody Fluorescein Conjugated - 200-502-M70
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4 Antibody, L3T4, T-cell differentiation antigen L3T4
Cd4
Mouse
Mouse
Rat
Fluorescein (FITC)
Monoclonal
GK1.5
IgG2b
Other
Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with Mouse CTL clone V4.
2-8 moles FITC per mole of IgG2b
Liquid (sterile filtered)
Wet Ice
Expiration date is six (6) months from date of opening.
0.5 mg/mL by UV absorbance at 280 nm
0.01 M Tris Cl, 0.15 M Sodium Chloride, pH 8.0
0.05% (w/v) Sodium Azide
0.05% BSA

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.