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Datasheet

CD4 Fluorescein Antibody

Rat Monoclonal GK1.5 IgG2b kappa

200-502-M70
500 µg
FC
Mouse
Rat
$359.00 /Per Item
Availability: Ships in approximately 14 days
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Product Details

Anti-CD4 (RAT) Monoclonal Antibody Fluorescein Conjugated - 200-502-M70
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4 Antibody, L3T4, T-cell differentiation antigen L3T4
Rat
Fluorescein (FITC)
Monoclonal
IgG2b

Target Details

Cd4  - View All Cd4 Products
Mouse
Other
Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with Mouse CTL clone V4.
Fluorescein conjugated CD4 Monoclonal Antibody was Protein G Purified and is directed against mouse CD4. Reactivity is observed against mouse CD4. Cross reactivity with CD4 from other sources has not been tested.

Application Details

FC
Anti-CD4 is tested in Flow Cytometry (Cell Surface) and useful for Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.

Formulation

Liquid (sterile filtered)
0.5 mg/mL by UV absorbance at 280 nm
0.01 M Tris Cl, 0.15 M Sodium Chloride, pH 8.0
0.05% (w/v) Sodium Azide
0.05% BSA

Shipping & Handling

Wet Ice
Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
Expiration date is six (6) months from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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