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BLM phospho S1296 Antibody
Rabbit Polyclonal
600-401-J56
100 µg
Lyophilized
Human
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-BLM pS1296 (RABBIT) Antibody - 600-401-J56
rabbit anti-BLM pS1296 Antibody, DNA helicase, RecQ-like type 2, RECQ2, RECQL3, Bloom syndrome protein
Rabbit
Polyclonal
IgG
Target Details
BLM - View All BLM Products
Human
Phosphorylation
Conjugated Peptide
Anti-BLM pS1296 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Bloom syndrome protein.
Anti-BLM pS1296 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of human S1296 residue. A BLAST analysis was used to suggest cross-reactivity with human and mouse based on 100% sequence homology. Cross-reactivity with BLM pS1296 from other sources has not been determined.
P54132 - UniProtKB
Application Details
Anti-BLM pS1296 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~159kDa corresponding to the appropriate cell lysate or extract.
Formulation
1.14mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
None
10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
100 µL
Restore with deionized water (or equivalent)
Shipping & Handling
Ambient
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
BLM pS1296 product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom´s syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom´s syndrome, namely cancer and diabetes. Anti-BLM pS1296 antibody is ideal for researchers interested in Epigenetics and Nuclear Signaling or DNA Damage & Repair research.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.