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Datasheet

ATP7B Antibody

Mouse Monoclonal S62-29 IgG1

ABIN1686618
100 µg
Liquid
WB, IHC, IF, IP
Human, Mouse, Rat
Mouse
$545.00 /Per Item
Availability: Ships in approximately 14 days
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene, A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage.

Product Details

Anti-ATPase Cu++ Transporting beta Polypeptide (ATP7B) (AA 3-21) Antibody - ABIN1686618
PWD, WC1, WD, WND, Atp7a, tx, Hts, PINA, Wd, ATP7B, ATPase copper transporting beta, ATPase, Cu++ transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide (Wilson disease), copper-transporting ATPase 2, ATP7B, Atp7b, atp7b, LOC592143
Mouse
Monoclonal
IgG1

Target Details

ATP7B  - View All ATP7B Products
Human, Mouse, Rat
Conjugated Peptide
Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2.
Anti-ATPase Cu++ Transporting beta Polypeptide (ATP7B) (AA 3-21) Antibody has been Protein G Purified and is reactive to human, Mouse, and Rat

Application Details

IF, IHC, IP, WB
Anti-ATPase Cu++ Transporting beta Polypeptide (ATP7B) (AA 3-21) Antibody is tested by Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), and Western Blotting (WB). Anti-ATPase detects ~160 kDa in rat brain membrane preparations. Optimal dilutions for assays should be determined by the user.

Formulation

1.0 mg/mL by UV absorbance at 280 nm
1X PBS, pH 7.4
0.09% (w/v) Sodium Azide
50% (v/v) Glycerol

Shipping & Handling

Wet Ice
Store at -20°C.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.