Human OSM - Oncostatin M ELISA Kit
            
                KOA0283
        
        
            
                1 Kit
        
            
                
                ELISA
            
                    
                
                Human
            
                    
                
                 15.6 pg/ml - 1000 pg/ml
            
                        
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Human OSM/Oncostatin M AccuSignal ELISA Kit - KOA0283                    
                
                
                    
                    
MGC20461, ONCM_HUMAN, Oncostatin M precursor, Oncostatin-M, OncostatinM, OSM, OTTMUSP00000005249, RP23-453B22.1                    
                
                
                    
                    
ELISA Kit                    
                
                
                    
                    
15.6 pg/ml - 1000 pg/ml                    
                
            Target Details
                    
                    
OSM                         - View All OSM Products
                            
                    
                
                
                    
                    
Human                                            
                
                
                    
                    
Expression system for standard: E.coli; Immunogen sequence:   A26R-220                                            
                
                
                    
                    
Natural and recombinant human OSM. There is no detectable cross-reactivity with other relevant proteins.                                            
                
                
                                P13725  - UniProtKB
                            
                                                    
                                NP_001306037.1  - NCBI Protein
                            
                                            Application Details
                        
                        
ELISA
                        
                    
                    
                        
                        
Useful in Sandwich ELISA for Quantitative Detection of Antigen.  Aliquot 0.1ml per well of the 1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml, 15.6pg/ml human OSM standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human OSM standard solution and each sample be measured in duplicate.
                        
                    
                                                    Formulation
                        
                        
Heparin Sodium                        
                    
                    
                        
                        
1 kit                         
                    
            Shipping & Handling
                    
                    
Wet Ice                    
                
                
                    
                    
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.                    
                
                
                    
                    
See kit insert for complete instructions.                    
                
        
                OSM(Oncostatin M) is a protein that in humans is encoded by the OSM gene. OSM is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. The OSM gene is mapped on 22q12.2. Of these cytokines it most closely resembles leukemia inhibitory factor(LIF) in both structure and function. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR.
            
        
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