Human Chitinase 3-like 1 - YKL-40 ELISA Kit
            
                KOA0602
        
        
            
                1 Kit
        
            
                
                ELISA
            
                    
                
                Human
            
                    
                
                 62.5 pg/ml - 4000 pg/ml
            
                        
    
        
        Shipping info:
        
    $50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
                    
                    
Human Chitinase 3-like 1/YKL-40 AccuSignal ELISA Kit - KOA0602                    
                
                
                    
                    
39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP-39, CGP39, CH3L1_HUMAN, CHI3L1, chitinase 3 like 1 (cartilage glycoprotein 39), chitinase 3 like 1, Chitinase 3 like protein 1 precursor, chitinase, Chitinase-3-like protein 1, GP 39, GP-39, GP39, HC gp39, HCGP 3P, hCGP-39, HCgp39, YKL 40, YKL-40, YKL40, YYL 40                    
                
                
                    
                    
ELISA Kit                    
                
                
                    
                    
62.5 pg/ml - 4000 pg/ml                    
                
            Target Details
                    
                    
CHI3L1                         - View All CHI3L1 Products
                            
                    
                
                
                    
                    
Human                                            
                
                
                    
                    
Expression system for standard: NSO; Immunogen sequence:  Y22-T383                                            
                
                
                    
                    
Natural and recombinant human Chitinase 3-like 1. There is no detectable cross-reactivity with other relevant proteins.                                            
                
                
                                P36222  - UniProtKB
                            
                                                    
                                NP_001267.2  - NCBI Protein
                            
                                            Application Details
                        
                        
ELISA
                        
                    
                    
                        
                        
Useful in Sandwich ELISA for Quantitative Detection of Antigen.  Aliquot 0.1ml per well of the 4000pg/ml, 2000pg/ml, 1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml human Chitinase 3-like 1 standard solutions into the precoated 96-well plate. Add 0.1ml of the sample diluent buffer into the control well (Zero well). Add 0.1ml of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or urine to each empty well. We recommend that each human Chitinase 3-like 1 standard solution and each sample is measured in duplicate.
                        
                    
                                                    Formulation
                        
                        
Heparin Sodium                        
                    
                    
                        
                        
1 Kit                         
                    
            Shipping & Handling
                    
                    
Wet Ice                    
                
                
                    
                    
Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.                    
                
                
                    
                    
See kit insert for complete instructions.                    
                
        
                Chitinase-3-like protein 1, also called CHI3L1 or YKL-40 is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. This gene is mapped to 1q32.1. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
            
        
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