Datasheet

ACVR2B protein-GST fusion

Name: ACVR2B protein-GST fusion
Brand: Rockland Immunochemicals
Price: 325.0 USD
Availability: OutOfStock

Item No. 009-001-R38

Size: 50 µg

Origin: Human

Expressed in: Sf9 cells

$665.00 /Per Item

20 µg $325.00

50 µg $665.00

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Background

ACVR2B or activin A receptor, type IIB is belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins that signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors (1). ACVR2B is help to regulate muscle growth (2). ACVR2B is a transmembrane protein that composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. ACVR2B Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, and Ser/Thr Kinase research.

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Specifications for ACVR2B protein-GST fusion

Product Details

Description: ACVR2B recombinant protein-GST fusion protein - 009-001-R38

Synonyms: ActR-IIB, ACTRIIB, MGC116908, Activin receptor type-2B, Activin receptor type IIB, ACVR2B

Species of Origin: Human

Expressed in: Sf9 cells

Type: Recombinant Protein

Target Details

Gene Name: ACVR2A

Purity/Specificity: Recombinant human ACVR2B (182-488) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry.

Database Links:

NCBI - NM_001616

Application Details

Application Note: ACVR2B Protein is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. ACVR2B Protein is suitable for use in Western Blot. Expect a band approximately ~ 61kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Formulation

Physical State: Liquid (sterile filtered)

Concentration: 0.1 µg/µL

Buffer: See application note.

Shipping & Handling

Shipping Condition: Dry Ice

Storage Condition: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Expiration: Expiration date is one (1) year from date of receipt.

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Disclaimer

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.