Rockland Immunochemicals, Inc. and Cytiva Life Sciences to launch PrismA ELISA Kit

NOVEMBER 10, 2022

The PrismA ELISA kit is an enzyme-linked immunosorbent assay designed to measure residual ligand leakage when using MabSelect PrismA™ chromatography resin and Fibro™ PrismA chromatography adsorbers. The kit is used during the development and manufacture of monoclonal antibody (mAb) biopharmaceuticals.

Purification of mAbs is routinely performed using protein A based affinity chromatography, which provides high capacity and consistent purification performance. When using protein A based purification techniques, it is a regulatory requirement to measure leached protein A ligand in the generated downstream material. For the most accurate results, it is important that manufacturers use a resin-matched standard to calibrate their assay.

This kit is the only commercial ELISA kit specifically designed for use with MabSelect PrismA™ resins and Fibro™ PrismA adsorbers. The kit contains all the necessary reagents required including the PrismA ligand optimized for use in ELISA, and polyclonal antibodies raised specifically against the PrismA ligand. We developed this kit with a focus on usability, robustness, and environmental sustainability.

Learn more about Impurity Detection ELISA Kits