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UBE2L6 (UBCH8) protein-HIS Epitope

009-001-U40S 009-001-U40
20 µg 50 µg
Liquid (sterile filtered) Liquid (sterile filtered)
H. sapiens (Human)
E. coli
This product is discontinued


UBE2L6 (UBCH8) or ubiquitin-conjugating enzyme E2L 6 is a member of the E2 ubiquitin-conjugating enzyme family which is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) and the selective physical interaction between E2 and E3 enzymes forms the basis of specificity for functionally distinct E2-E3 combinations (1). UBE2L6 and the ubiquitin-ligase SIAH1 physically interact with and target FLT3-ITD for proteasomal degradation (2). UBE2L6 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.

Product Details

UBE2L6(UBCH8) recombinant protein-HIS Epitope - 009-001-U40
RIG-B, UBCH8, Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6
E. coli
Recombinant Protein

Target Details

H. sapiens (Human)
Recombinant full length human UBE2L6 (UBCH8) was expressed in E. coli cells using an N-Terminal his epitope. The purity was determined to be >85% by densitometry.
?term=NM_004223 - Gene ID

Application Details

UBE2L6 Protein is stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. UBE2L6 Protein is suitable for use in Western Blot. Expect a band approximately ~17kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.


0.1 µg/µL
See application note.

Shipping & Handling

Dry Ice
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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