UBE2B protein-HIS Epitope
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Datasheet

UBE2B protein-HIS Epitope

009-001-U28S 009-001-U28
20 µg 50 µg
Human
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$165.00 /Per Item
$256.00 /Per Item
20 µg $165.00
50 µg $256.00
Availability: Ships in approximately 30 days Availability: Ships in approximately 30 days
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Description

Background

UBE2B or ubiquitin-conjugating enzyme E2B is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair. UBE2B is specifically important during chronic low-dose ultraviolet exposure to prevent counterproductive DNA checkpoint activation and allow cells to proliferate normally (1). The activity of UBE2B is required within the synaptonemal complex and for meiotic recombination in spermatocytes (2). Experimental inactivation of the UBE2B gene in mice causes male infertility. UBE2B Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.

Application Note

UBE2B Protein is stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. UBE2B Protein is suitable for use in Western Blot. Expect a band approximately ~17kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Purity/Specificity

Recombinant full length human UBE2B was expressed in E. coli cells using an N-Terminal his epitope. The purity was determined to be >90% by densitometry.

UBE2B recombinant protein-HIS Epitope - 009-001-U28
E2-17kDa, HHR6B, HR6B, RAD6B, UBC2, Ubiquitin-conjugating enzyme E2 B
UBE2B
Human
E. coli
Protein
Recombinant Protein
Liquid (sterile filtered)
0.1 µg/µL
See application note.
Dry Ice
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Expiration date is one (1) year from date of opening.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.