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ACVR2A protein-HIS Epitope
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Description
Background
ACVR2A encodes activin A type II receptor that are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins is an autocrine/paracrine regulator in the human placenta (1). ACVR2A is highly expressed in human brain and ovary (2). Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. ACVR2A Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, and Ser/Thr Kinase research.
Application Note
ACVR2A Protein is stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. ACVR2A Protein is suitable for use in Western Blot. Expect a band approximately ~ 47kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
Purity/Specificity
Recombinant human ACVR2A (161-end) was expressed by baculovirus in Sf9 insect cells using an N-Terminal his epitope. The purity was determined to be >90% by densitometry.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.