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Fibrinogen Antibody

Mouse Monoclonal 4F7 IgG1

100 µL
$523.00 /Per Item
Availability: Ships in approximately 14 days
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$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.


Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains respectively. In this way fibrinogen is converted into fibrin which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI thromboembolism and thromboses of arteries and veins since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3mg/mL. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.

Product Details

Anti-Fibrinogen (MOUSE) Antibody - ABIN722856
FGA, FGA protein, FGB, FGG, Fib2, Fibrin alpha chain, Fibrinogen A alpha polypeptide, Fibrinogen A alpha polypeptide chain, Fibrinogen alpha chain Fibrinogen B, alpha polypeptide Fibrinogen, beta chain Fibrinogen G, alpha polypeptide Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405

Target Details

Native Protein
Fibrinogen from human plasma.
Purified by Protein G.

Application Details

Anti-Fibrinogen Antibody is suitable for use in Immunofluorescence (Paraffin-embedded Sections) (IF-P)) and Immunohistochemistry (Paraffin-embedded Sections) (IHC-P)). This product is in 0.01M TBS pH7.4.


1.0 µg/µL by UV absorbance at 280 nm
Proclin is added as an antimicrobial agent.
50% (v/v) Glycerol

Shipping & Handling

Wet Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use. Stable for 12 months from date of receipt.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.