Fab and F(ab')2 Fragment Antibodies are essential for achieving precise results in immunological assays. These fragments are engineered to enhance experimental accuracy by eliminating nonspecific interactions, thanks to their unique structural modifications. Fab fragments, at about 50 kDa, offer monovalent binding that avoids cross-reactivity, while F(ab')2 fragments, around 110 kDa, provide bivalent binding without Fc-mediated nonspecific binding. Key benefits include:
Targeted precision: Monovalent and bivalent bindings ensure accurate antigen detection
Clarity in results: Absence of the Fc region reduces background noise
Versatile use: Effective in a variety of experimental contexts